Frontiers in Molecular Neuroscience, 2020 A number of studies implicate biogenic amines in regulating circadian rhythms. In particular, dopamine and serotonin influence the entrainment of circadian rhythms to daily food availability.
Christian M. Gallardo +2 more
doaj +1 more source
Serotonin 1B Receptor Gene (HTR1B) Methylation as a Risk Factor for Callous-Unemotional Traits in Antisocial Boys. [PDF]
PLoS ONE, 2015 The serotonin system is thought to play a role in the aetiology of callous-unemotional (CU) traits in children. Previous research identified a functional single nucleotide polymorphism (SNP) from the promoter region of the serotonin 1B receptor gene as ...
Caroline Moul +4 more
doaj +1 more source
Fluoxetine: a case history of its discovery and preclinical development [PDF]
, 2014 Introduction: Depression is a multifactorial mood disorder with a high prevalence worldwide. Until now, treatments for depression have focused on the inhibition of monoaminergic reuptake sites, which augment the bioavailability of monoamines in the CNS ...
Bel N +20 more
core +2 more sources
Enhanced sensitivity of postsynaptic serotonin-1A receptors in rats and mice with high trait aggression [PDF]
, 2001 Individual differences in aggressive behaviour have been linked to variability in central serotonergic activity, both in humans and animals. A previous experiment in mice, selectively bred for high or low levels of aggression, showed an up-regulation of ...
Boer, Sietse F. de, +5 more
core +1 more source
Glycogen Synthase Kinase-3 is an intermediate modulator of serotonin neurotransmission
Frontiers in Molecular Neuroscience, 2011 Serotonin is a neurotransmitter with broad functions in brain development, neuronal activity, and behaviors; and serotonin is the prominent drug target in several major neuropsychiatric diseases.
Xiaohua eLi, Abigail ePolter
doaj +1 more source
Serotonin Regulates Lipogenesis in Adipose Tissues through Serotonin Receptor 2A [PDF]
Endocrinology and Metabolism, 2020 Background Obesity is defined as excessive fat mass and is a major cause of many chronic diseases such as diabetes, cardiovascular disease, and cancer. Increasing energy expenditure and regulating adipose tissue metabolism are important targets for the ...
Ko Eun Shong +4 more
doaj +1 more source
Heliyon, 2019 The neurotropic pathogen Toxoplasma gondii infects about one-third of the human population. Both acute and chronic (latent or life-long) forms of toxoplasmosis are associated with specific neurologic and neuropsychiatric symptoms.
Hasan Tarik Atmaca
doaj +1 more source
Function and distribution of 5-HT2 receptors in the honeybee (Apis mellifera). [PDF]
PLoS ONE, 2013 BACKGROUND: Serotonin plays a pivotal role in regulating and modulating physiological and behavioral processes in both vertebrates and invertebrates. In the honeybee (Apis mellifera), serotonin has been implicated in division of labor, visual processing,
Markus Thamm +6 more
doaj +1 more source
Enhanced self-administration of the CB1 receptor agonist WIN55,212-2 in olfactory bulbectomized rats: evaluation of possible serotonergic and dopaminergic underlying mechanisms [PDF]
, 2014 Depression has been associated with drug consumption, including heavy or problematic cannabis use. According to an animal model of depression and substance use disorder comorbidity, we combined the olfactory bulbectomy (OBX) model of depression with ...
Amchova P +11 more
core +1 more source
Glucocorticoids Inhibit Basal and Hormone-Induced Serotonin Synthesis in Pancreatic Beta Cells. [PDF]
PLoS ONE, 2016 Diabetes is a major complication of chronic Glucocorticoids (GCs) treatment. GCs induce insulin resistance and also inhibit insulin secretion from pancreatic beta cells. Yet, a full understanding of this negative regulation remains to be deciphered.
Moina Hasni Ebou +10 more
doaj +1 more source