Results 261 to 270 of about 71,732 (355)

Methods for Improving Settlement and Metamorphosis of Shelled Marine Mollusks in Aquaculture: A Review

Aquaculture, Fish and Fisheries, Volume 6, Issue 2, April 2026.
Settlement and metamorphosis are key developmental hurdles in marine mollusk aquaculture. Environmental signals (such as biofilms, algae, and signals from conspecifics) and biochemical pathways (including nitric oxide, thyroid hormones, catecholamines, and GABA) regulate the transition of larvae into benthic juveniles. Combining ecological observations
Angelica R. Valdez, Mitchell P. Marabella, Jon‐Paul Bingham   +2 more
wiley   +1 more source

Novel 2-Aminotetralin and 3-AminoChroman Derivatives as Selective Serotonin 5-HT₇ Receptor Agonists and Antagonists

, 2004
Pär Holmberg, Daniel Sohn, Robert Leideborg, Patrizia Caldirola, Pavel Zlatoidsky, Sverker Hanson, Nina Mohell, Susanne Rosqvist, Gunnar Nordvall, Anette M. Johansson, Rolf Johansson   +10 more
openalex   +1 more source

Proteomic profiling of brain organoids and extracellular vesicles identifies early Alzheimer's disease biomarkers and drug response heterogeneity

Alzheimer's &Dementia, Volume 22, Issue 4, April 2026.
Abstract INTRODUCTION Alzheimer's disease (AD) exhibits high genetic and clinical heterogeneity that limits therapeutic success. Patient‐derived brain organoids and their extracellular vesicles (EVs) provide physiologically relevant models to study disease mechanisms and individualized drug responses.
Rachel J. Boyd, Daiyun Dong, Ram Sagar, Anton Iliuk, Waqar Ahmed, Xenia Androni, Anton P. Porsteinsson, Paul B. Rosenberg, Constantine G. Lyketsos, Kenneth W. Witwer, Vasiliki Mahairaki   +10 more
wiley   +1 more source

AI-derived therapeutic development of a serotonin receptor-targeting drug for the treatment of opioid use disorder. [PDF]

Proc Natl Acad Sci U S A
Lallai V, Kho S, Martin AC, Fowler JP, Roach ML, Wang K, Laumann KN, Morrison TG, Palaniappan M, Bautista M, Mogul AS, Cheepluesak JE, Shrestha B, Lade DM, Lagomarsino JE, Narayan V, Uffens J, Lernhardt W, Mirzaei S, Jenkins I, Zavala AR, Lakey JRT, Tinder R, Fowler CD.   +23 more
europepmc   +1 more source

The electrophysiological effects of the serotonin 1A receptor agonist buspirone in emotional face processing

, 2015
Fosco Bernasconi, Michael Kometer, Thomas Pokorny, Erich Seifritz, Franz X. Vollenweider   +4 more
openalex   +2 more sources

Immune–proteo–metabolomic changes link to Aβ and tau pathology in Alzheimer disease

Alzheimer's &Dementia, Volume 22, Issue 4, April 2026.
Abstract INTRODUCTION Tryptophan metabolism is increasingly implicated in Alzheimer's disease (AD), particularly through aryl hydrocarbon receptor (AhR) ligands that influence neuroinflammation. However, their relationships with core AD pathology—amyloid‐β (A) and tau (T) deposition—and associated immune–proteomic alterations remain unclear. METHODS We
Meng Wang, Maria Buthut, Jenny Meinhardt, Carolin Otto, Gerardina Gallaccio, Camila Fernández‐Zapata, Matteo Teves, Claudia Samol, Katja Dettmer, Simon Heckscher, Sakshi Kamboj, Yozlem Bahar, Christian Conrad, Christian Böttcher, Desiree Kunkel, Klemens Ruprecht, Friedemann Paul, Peter J. Oefner, Helena Radbruch, Wolfram Gronwald, Harald Prüß, Chotima Böttcher   +21 more
wiley   +1 more source

TRPV4-Mast Cell Interactions in Neurogenic Inflammation and Chronic Diseases: A Narrative Review. [PDF]

Int J Mol Sci
Fouani M, Kumari S, Charles A, Wickware C, Moore AA, Cho CH, Abraham SN, Moore CD.   +7 more
europepmc   +1 more source

Drug‐Induced Raynaud's Phenomenon and Underlying Mechanism: A Disproportionality Analysis From the World Health Organization Pharmacovigilance Database

Arthritis &Rheumatology, Volume 78, Issue 4, Page 985-992, April 2026.
Objectives The aim of this study is to generate hypotheses about unknown drugs associated with the onset or worsening of Raynaud's phenomenon (RP) and to explore their potential pathophysiologic mechanisms through a mixed disproportionality/clustering analysis from the World Health Organization (WHO) pharmacovigilance database.
Alex Hlavaty, Loubna Dari, Jean‐Luc Cracowski, Matthieu Roustit, Charles Khouri   +4 more
wiley   +1 more source

The renaissance of research on psychedelics in child and adolescent psychopharmacology. [PDF]

Child Adolesc Psychiatry Ment Health
Crocq MA, Auby P.
europepmc   +1 more source

Psilocybin Production With Genetically Modified Aspergillus nidulans Under Pressurized Conditions

Biotechnology and Bioengineering, Volume 123, Issue 4, Page 886-898, April 2026.
Shake flask cultures of psilocybin‐producing A. nidulans were investigated with respect to nitrogen source, rheology, power input, and oxygen availability, and subsequently scaled to a stirred tank reactor scale based on specific power input to develop and optimize a pressurized bioprocess.
Sophie Weiser, Sidney Jung, Bettina Bardl, Johann E. Kufs, Slavica Janevska, Vito Valiante, Dirk Hoffmeister, Lars Regestein   +7 more
wiley   +1 more source