Results 211 to 220 of about 207,072 (360)

Effects of fenfluramine and sigma‐1‐dependent pharmacological and genetic modulation in a mouse kindling model

Epilepsia, EarlyView.
Abstract Objective Sigma‐1 is a chaperone protein that serves as a key homeostatic regulator, implicated in neuronal excitability and seizure control. Positive allosteric modulators offer a use‐dependent means to enhance Sigma‐1 activity, potentially with favorable tolerability compared to direct agonists.
Eva‐Lotta von Rüden, Verena Buchecker, Amelie Wagner, Victoria M. Stocker, Liga Zvejniece, Heidrun Potschka   +5 more
wiley   +1 more source

Serotonin Receptors in Areas of the Emotion Regulation Network in Human and Rat Brains-A Comparative Autoradiographic Study. [PDF]

J Comp Neurol
Kuckertz A, Zhao L, Kedo O, Amunts K, PalomeroGallagher N.   +4 more
europepmc   +1 more source

Possible psychedelic therapeutic mechanism. [PDF]

Science, 2023
Hess EM, Gould TD.
europepmc   +1 more source

Gut‐microbiota‐brain Axis and post‐traumatic epilepsy

Epilepsia Open, EarlyView.
Abstract There has been growing evidence that perturbations in gut‐microbiota‐brain axis (GMBA) are involved in mechanisms of chronic sequelae of traumatic brain injury (TBI). This review discusses the connection between GMBA and post‐traumatic epilepsy (PTE), the latter being a common outcome of TBI.
Andrey Mazarati
wiley   +1 more source

Clebopride stimulates 5-HT₄-serotonin receptors in the human atrium. [PDF]

Naunyn Schmiedebergs Arch Pharmacol
Abella LMR, Neumann J, Hofmann B, Kirchhefer U, Gergs U.   +4 more
europepmc   +1 more source

Serotonin receptors and their association with the immune system in the gastrointestinal tract of weaning piglets. [PDF]

Porcine Health Manag, 2022
Fabà L, de Groot N, Ramis G, Cabrera-Gómez CG, Doelman J.   +4 more
europepmc   +1 more source

Cerebral 5-HT _2A Receptor and Serotonin Transporter Binding in Humans Are Not Affected by the val66met BDNF Polymorphism Status or Blood BDNF Levels [PDF]

, 2010
Anders B. Klein, Viktorija Trajkovska, David Erritzøe, Steven Haugbøl, Jacob Madsen, William F.C. Baaré, Susana Aznar, Gitte M. Knudsen   +7 more
openalex   +1 more source

Inherited metabolic epilepsies–established diseases, new approaches

Epilepsia Open, EarlyView.
Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley   +1 more source

In search of a photoswitchable drug for serotonin receptors: a molecular dynamics simulation study. [PDF]

RSC Adv
Dhaliwal AS, Verma A, Mondal P.
europepmc   +1 more source

On Associations between Fear-Induced Aggression, Bdnf Transcripts, and Serotonin Receptors in the Brains of Norway Rats: An Influence of Antiaggressive Drug TC-2153. [PDF]

Int J Mol Sci, 2023
Moskaliuk VS, Kozhemyakina RV, Khomenko TM, Volcho KP, Salakhutdinov NF, Kulikov AV, Naumenko VS, Kulikova EA.   +7 more
europepmc   +1 more source