Results 191 to 200 of about 207,072 (360)

RORγt‐APCs: The New Masters of Oral Tolerance

Barrier Immunity, EarlyView.
ABSTRACT Oral tolerance is defined by the hypo‐responsiveness of our body to fed antigens, and its failure can lead to immune‐mediated diseases, such as allergy, chronic inflammation and autoimmune diseases. Decades of research have demonstrated that antigen‐presenting cells (APCs) promote oral tolerance by inducing regulatory T cells (Tregs) and/or ...
Thierry Gauthier, WanJun Chen
wiley   +1 more source

Molecular insights into the regulation of constitutive activity by RNA editing of 5HT_2C serotonin receptors. [PDF]

Cell Rep, 2022
Gumpper RH, Fay JF, Roth BL.
europepmc   +1 more source

Single neuron serotonin receptor subtype gene expression correlates with behaviour within and across three molluscan species [PDF]

, 2018
Arianna N. Tamvacakis, Adriano Senatore, Paul S. Katz   +2 more
openalex   +1 more source

The β integrin modulates serotonin sensitivity via NPxY motifs to regulate egg laying and mechanosensation behaviors in Caenorhabditis elegans

Developmental Dynamics, EarlyView.
Abstract Background Integrin is an αβ heterodimeric receptor to the extracellular matrix; its binding to the matrix recruits focal adhesions to two NPxY motifs, the tyrosine phosphorylation sites in the cytoplasmic domain. Studies found that replacing tyrosines (Y) with phenylalanines (F) in the motif of β1 integrin displayed little developmental or ...
Josh Haram Bumm, Daniel Dogeon Lee, Zhongqiang Qiu, Angela Haeun Choi, Meghana Kolluri, Michael J. Olsen, Lianzijun Wang, Myeongwoo Lee   +7 more
wiley   +1 more source

Distribution of Metabotropic Serotonin Receptors in GABAergic and Glutamatergic Neurons in the Auditory Midbrain. [PDF]

J Comp Neurol
Galindo KL, Nazir ZA, Silveira MA.
europepmc   +1 more source

An initial three-component pharmacophore for specific serotonin-3 receptor ligands

, 1990
James P. Rizzi, A. Nagel, Terry Rosen, Stafford McLean, Thomas Seeger   +4 more
openalex   +1 more source

Cannabidiol in Anorexia Nervosa: A Double‐Blind Randomized Placebo Controlled Pilot Study to Test Safety, Pharmacokinetics, and Symptom Change

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Anorexia nervosa (AN) is a severe psychiatric disorder marked by an intense fear of gaining weight and persistent body dissatisfaction, both during periods of underweight and after weight restoration. The endocannabinoid system may offer therapeutic benefits, particularly in reducing anxiety.
Neha Sahota, David J. Grelotti, Tyler Nguyen, Walter H. Kaye, Skylar Swindle, Raymond Suhandynata, Spencer Seely, Megan E. Shott, Guido K. W. Frank   +8 more
wiley   +1 more source

Microglial Expression of Serotonin Receptors Reveals Parallel Regulation of 5-HT2b and BDNF in the Rat Hippocampus. [PDF]

Cells
Turkin A, Sidorova M, Kurilova E, Alenina N, Tuchina O, Klempin F.   +5 more
europepmc   +1 more source

Activity of Mitragyna speciosa ("Kratom") Alkaloids at Serotonin Receptors. [PDF]

J Med Chem, 2021
León F, Obeng S, Mottinelli M, Chen Y, King TI, Berthold EC, Kamble SH, Restrepo LF, Patel A, Gamez-Jimenez LR, Lopera-Londoño C, Hiranita T, Sharma A, Hampson AJ, Canal CE, McMahon LR, McCurdy CR.   +16 more
europepmc   +1 more source

Analgesic actions of N ‐arachidonoyl‐serotonin, a fatty acid amide hydrolase inhibitor with antagonistic activity at vanilloid TRPV1 receptors [PDF]

, 2007
Sabatino Maione, Luciano De Petrocellis, Vito de Novellis, Aniello Schiano Moriello, Stefania Petrosino, Enza Palazzo, Francesca Rossi, David F. Woodward, Vincenzo Di Marzo   +8 more
openalex   +1 more source