Results 191 to 200 of about 748,112 (249)

Fenfluramine in Rett syndrome: A multidimensional clinical study

Epilepsia Open, EarlyView.
Abstract Objective Rett syndrome (RTT) is a severe neurodevelopmental disorder frequently associated with drug‐resistant epilepsy, autonomic dysfunction, respiratory abnormalities, sleep disturbances, and behavioral impairment. Fenfluramine has shown efficacy in developmental and epileptic encephalopathies and may provide broader therapeutic benefits ...
Elena Gonzalez‐Alguacil, Nuria Lamagrande Casanova, Manuel Luján Bonete, David Mansilla Lozano, Juan José García Peñas, María Ballará Petitbó, Rocío Trincado Lamuño, Verónica Cantarín‐Extremera, Raquel Díaz Conejo, César Rodríguez Sánchez, Adrián García Ron, Víctor Soto Insuga   +11 more
wiley   +1 more source

Psilocybin Facilitates Fear Extinction: Importance of Dose, Context, and Serotonin Receptors. [PDF]

ACS Chem Neurosci
Woodburn SC, Levitt CM, Koester AM, Kwan AC.   +3 more
europepmc   +1 more source

Genetic developmental and epileptic encephalopathies in adulthood: Gaps in evidence and care

Epilepsia Open, EarlyView.
Abstract Developmental and epileptic encephalopathies (DEEs) are a heterogeneous group of the most severe epilepsies, characterized by seizure onset and neurodevelopmental delay in infancy or childhood, often with additional neurological and systemic comorbidities.
Alex M. Dudley, Peter Widdess‐Walsh, Christine Linehan, Danielle M. Andrade, Norman Delanty, Patrick B. Moloney   +5 more
wiley   +1 more source

Multitarget-Directed Ligands Hitting Serotonin Receptors: A Medicinal Chemistry Survey. [PDF]

Pharmaceuticals (Basel)
Ghafir El Idrissi I, Santo A, Lacivita E, Leopoldo M.   +3 more
europepmc   +1 more source

Physicochemical, Functional, and Health‐Promoting Properties of Processed Nettle (Urtica Dioica) Leaves: A Review

Future Postharvest and Food, EarlyView.
Stinging nettle (Urtica dioica L.) leaves are a nutrient‐dense source of proteins, dietary fiber, chlorophylls, carotenoids, and phenolic compounds. Processing technologies enable the production of powders and extracts for incorporation into bakery, beverage, dairy, and nutraceutical products; however, challenges remain regarding sensory quality ...
Mary Nkongho Tanyitiku, Rakshya Pandit, Mihiri Vanniarachchy   +2 more
wiley   +1 more source

Zacopride stimulates 5-HT₄ serotonin receptors in the human atrium. [PDF]

Naunyn Schmiedebergs Arch Pharmacol
Neumann J, Hesse C, Hofmann B, Gergs U.
europepmc   +1 more source

Medicated Optimism

Health Economics, EarlyView.
ABSTRACT Do people experiencing depression form accurate expectations about losing their jobs? Linking Estonian panel survey data to administrative employment, diagnosis, and prescription records, I track within‐person changes in expected job loss and subsequent realized job loss as individuals move into and out of depression and depression medication.
Penglong Li
wiley   +1 more source

Exploring the Potential of Coumarin Derivatives on Serotonin Receptors 5-HT_1A and 5HT_2A. [PDF]

Int J Mol Sci
Ostrowska K, Horosz G, Kruk K, Sieroń B, Leśniak A, Czartoryska Z, Bujalska-Zadrożny M, Milenkovic D, Trzaskowski B.   +8 more
europepmc   +1 more source

Pharmacological effects of gastrodin: Insight into neurological diseases and mechanism in ferroptosis and pyroptosis

Ibrain, Volume 11, Issue 1, Page 74-83, Spring 2025.
Pharmacological effects of gastrodin include prevention and treatment of cognitive decline and reperfusion injuries, anticonvulsion, antiepilepsy, antidepressants, and analgesia, which are related to antiferroptosis and antipyroptosis. Abstract Gastrodin, as an effective monomer of gastrodia elata, plays a significant role in anti‐inflammatory ...
Xue Zheng, Jing Li, Zhao‐Qiong Zhu
wiley   +1 more source

Anxiety disorder and anxiolytic pharmacotherapy during pregnancy: The impact on pregnancy outcomes

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective This study determines the contributions of anxiety disorder and anxiolytic pharmacotherapy on perinatal outcomes and examines prescribing trends during pregnancy. Methods A retrospective cohort study was conducted at a single tertiary medical center between 2013 and 2024.
Sher Goaz Melet, Chagit Kliger, Daniel Gabbai, Danna Englender, Yariv Yogev, Omri Dominsky   +5 more
wiley   +1 more source