Results 191 to 200 of about 708,936 (290)
Multitarget-Directed Ligands Hitting Serotonin Receptors: A Medicinal Chemistry Survey. [PDF]
Ghafir El Idrissi I +3 more
europepmc +1 more source
ABSTRACT Postoperative ileus (POI) is a frequent complication after surgical procedures, predominantly manifesting as aberrant gastrointestinal motility, which markedly extends the duration of postoperative recovery for patients. The clinical duration of POI is typically modulated by intricate inflammatory cascades, with mast cells assuming a critical ...
Tian‐le Zhang +4 more
wiley +1 more source
Exploring the Potential of Coumarin Derivatives on Serotonin Receptors 5-HT<sub>1A</sub> and 5HT<sub>2A</sub>. [PDF]
Ostrowska K +8 more
europepmc +1 more source
Zacopride stimulates 5-HT4 serotonin receptors in the human atrium. [PDF]
Neumann J, Hesse C, Hofmann B, Gergs U.
europepmc +1 more source
Pharmacological effects of gastrodin include prevention and treatment of cognitive decline and reperfusion injuries, anticonvulsion, antiepilepsy, antidepressants, and analgesia, which are related to antiferroptosis and antipyroptosis. Abstract Gastrodin, as an effective monomer of gastrodia elata, plays a significant role in anti‐inflammatory ...
Xue Zheng, Jing Li, Zhao‐Qiong Zhu
wiley +1 more source
Mosapride stimulates human 5-HT4-serotonin receptors in the heart. [PDF]
Neumann J, Hesse C, Hofmann B, Gergs U.
europepmc +1 more source
Serotonin neuromicrobiology: Psychobiotic modulation of the gut–brain axis for mental health
An overview of Psychobiotics and Tryptophan metabolism: A serotonin‐kynurenine crosstalk shaping the Gut‐Brain axis. IDO1, Indoleamine 2,3‐dioxygenase 1; 5‐HT3, 5‐hydroxytryptamine type 3; IFN‐γ, Interferon‐gamma; TNF‐α, Tumor necrosis factor‐alpha; IL‐1β, Interleukin‐1 beta; IL‐6, Interleukin 6; Trp, Tryptophan; 5‐HT, 5‐hydroxy‐tryptamine; 5‐HTP, 5 ...
Nidhi Mandloi +4 more
wiley +1 more source
Abstract Premature ovarian insufficiency (POI) and early menopause (EM) affect millions of women worldwide. Compared with normal menopause, they confer a longer duration of estrogen deficiency and are associated not only with a shorter lifespan, but with a reduced healthspan, owing to an increased risk of cardiovascular, skeletal, cognitive and ...
Chiara Benedetto +8 more
wiley +1 more source

