Results 201 to 210 of about 207,072 (360)

Serotonin receptor [PDF]

Science-Business eXchange, 2011
openaire   +1 more source

Commonalities of platelet dysfunction in heart failure with preserved ejection fraction and underlying comorbidities

ESC Heart Failure, Volume 12, Issue 2, Page 1013-1028, April 2025.
Abstract Heart failure with preserved ejection fraction (HFpEF) is characterized by a lack of a specific targeted treatment and a complex, partially unexplored pathophysiology. Common comorbidities associated with HFpEF are hypertension, atrial fibrillation, obesity and diabetes.
Giorgia D'Italia, Blanche Schroen, Judith M.E.M. Cosemans   +2 more
wiley   +1 more source

Felcisetrag stimulates 5-HT₄-serotonin receptors in the human atrium. [PDF]

Naunyn Schmiedebergs Arch Pharmacol
Abella LMR, Neumann J, Hofmann B, Kirchhefer U, Gergs U.   +4 more
europepmc   +1 more source

Cardiovascular effects of bufotenin on human 5-HT₄ serotonin receptors in cardiac preparations of transgenic mice and in human atrial preparations. [PDF]

Naunyn Schmiedebergs Arch Pharmacol, 2023
Neumann J, Schulz N, Fehse C, Azatsian K, Čináková A, Marušáková M, Hofmann B, Gergs U.   +7 more
europepmc   +1 more source

Metabolic abnormalities and reprogramming in cats with naturally occurring hypertrophic cardiomyopathy

ESC Heart Failure, Volume 12, Issue 2, Page 1256-1270, April 2025.
Abstract Background and aims The heart is a metabolic organ rich in mitochondria. The failing heart reprograms to utilize different energy substrates, which increase its oxygen consumption. These adaptive changes contribute to increased oxidative stress.
Qinghong Li, Max Homilius, Erin Achilles, Laura K. Massey, Victoria Convey, Åsa Ohlsson, Ingrid Ljungvall, Jens Häggström, Brittany Vester Boler, Pascal Steiner, Sharlene Day, Calum A. MacRae, Mark A. Oyama   +12 more
wiley   +1 more source

Targeting serotonin receptors with phytochemicals - an in-silico study. [PDF]

Sci Rep
Elalouf A, Rosenfeld AY, Maoz H.
europepmc   +1 more source

Polymorphisms of the serotonin receptors genes in patients with bruxism: a systematic review. [PDF]

J Appl Oral Sci, 2022
Campello CP, Moraes SLD, Vasconcelos BCDE, Lima ELS, Pellizzer EP, Lemos CAA, Muniz MTC.   +6 more
europepmc   +1 more source

An n‐of‐1 gene‐directed drug repurposing trial for an ultrarare genetic condition

Epilepsia, EarlyView.
Abstract Objective Gain‐of‐function (GoF) variants in the KCNC1 potassium channel subunit gene (Kv3.1) cause motor/cognitive delays and hypotonia and have been associated with seizures. Fluoxetine has inhibitory effects on Kv3.1. However, open‐label nonrandomized administration is insufficient to guide clinical decision‐making in ultrarare conditions ...
Vedika Jha, Christina Tsetsos, Mark Bedford, Gregory Costain, Sunita Vohra, Juan Pablo Diaz Martinez, Elise Heon, Jacob Vorstman, Carolina Gorodetsky, Ajoy Vincent, Jesiqua Rapley, Lori Anderson, Evdokia Anagnostou, Danielle A. Baribeau   +13 more
wiley   +1 more source

Bromopride stimulates 5-HT₄-serotonin receptors in the human atrium. [PDF]

Naunyn Schmiedebergs Arch Pharmacol
Abella LMR, Neumann J, Hofmann B, Gergs U.   +3 more
europepmc   +1 more source

Serotonin receptors contribute to dopamine depression of lateral inhibition in the nucleus accumbens. [PDF]

Cell Rep, 2022
Burke DA, Alvarez VA.
europepmc   +1 more source