Results 51 to 60 of about 2,706,588 (275)

Serotonin syndrome: a rare undiagnosed cause of hyperpyrexia

The Egyptian Journal of Internal Medicine, 2023
Serotonin syndrome (SS) is a rare but potentially life-threatening condition, and it is caused by increasing serotonergic activities. It is an underdiagnosed and under-reported condition.
Hamdy Ibrahim, Safwat Abdel Maksod, Magdy Khorshed, Hanan Rady, Ahmed Alsisi, Adel Mohamed, Omar Alkassas, Marwa Haron, Suzan Saied   +8 more
doaj   +1 more source

Delayed onset serotonin syndrome in the setting of polypharmacy

Journal of Community Hospital Internal Medicine Perspectives, 2021
Serotonin syndrome is a rare but well-known condition that can be life-threatening if not diagnosed early. Onset is usually within 4 to 13 h of starting the offending medication.
Roshan Acharya, Smita Kafle, Sijan Basnet, DilliRam Poudel, Sushil Ghimire   +4 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Serotonin: beyond menopause [PDF]

Romanian Journal of Medical Practice, 2016
Serotonin is a brain neurotransmitter, a local gut-produced pro-kinetic agent and a platelets-released monoamine with haemostasis role. We focus on revealing the serotonin interferences with menopause mainly related to climacteric syndrome and bone ...
Mara Carsote, Eugenia Nedeltcheva Petrova, Otilia Radu, Andrei Goldstein, Adina Ghemigian, Ana Valea   +5 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni, Cecile Pagan, Antony Citterio‐Quentin, Isabelle Rouvet, Giulia Dingeo, Cyril Hanin, Claudine Laurent‐Levinson, Samia Pichard, Bénédicte Héron, Clément Gourguechon, Daniele Mandia, Jerome Guitton, Carole Lacout, Nicolas Schleinitz, Florient Potier, Olivier Flabeau, Elsa Besse‐Pinot, Foudil Lamari, Magali Pettazzoni, Yann Nadjar   +19 more
wiley   +1 more source

Serotonin Syndrome [PDF]

MedUNAB, 2004
The serotonin syndrome is a clinical condition associated with serotonin agonists, prescribed to treat some psychiatric and non psychiatric diseases like affective, anxiety and pain disorders.
Harold Muñoz Cortés, Adriana Vargas Rueda   +1 more
doaj  

Serotonin Syndrome in the Setting of Lamotrigine, Aripiprazole, and Cocaine Use

Case Reports in Medicine, 2015
Serotonin syndrome is a potentially life-threatening condition associated with increased serotonergic activity in the central nervous system. It is classically associated with the simultaneous administration of two serotonergic agents, but it can occur ...
Anupam Kotwal, Sarah L. Cutrona
doaj   +1 more source

Slow on the Uptake, Progression to Heartbreak

Journal of Investigative Medicine High Impact Case Reports, 2020
The prevalence of serotonin syndrome increases over the past several years as more serotonergic medications are being used in clinical practice. It is a potentially lethal condition caused by excessive serotonergic activity.
Ashley K. Binder MD, John P. Haydek MD, Siddhant Parihar MD, Chelsea E. Modlin MD, Manasi Tannu MD, Amalia Aldredge MD, Viranuj Sueblinvong MD   +6 more
doaj   +1 more source

Monoaminoxidase inhibitors as a cause of serotonin syndrome – a systematic case review based on meta-analytic principles

European Psychiatry, 2021
Introduction Serotonin syndrome (SS) is a toxic state characterized by increased serotonin activity. It has been suggested that severe serotonin syndrome usually involves monoaminoxidase inhibitors (MAOIs). Objectives To quantify in how far severe SS
P. Truedson, M. Ott, H. Wikström, M. Maripuu, K. Lindmark, U. Werneke   +5 more
doaj   +1 more source