Results 91 to 100 of about 2,926,392 (292)

Metabolic abnormalities and reprogramming in cats with naturally occurring hypertrophic cardiomyopathy

ESC Heart Failure, Volume 12, Issue 2, Page 1256-1270, April 2025.
Abstract Background and aims The heart is a metabolic organ rich in mitochondria. The failing heart reprograms to utilize different energy substrates, which increase its oxygen consumption. These adaptive changes contribute to increased oxidative stress.
Qinghong Li, Max Homilius, Erin Achilles, Laura K. Massey, Victoria Convey, Åsa Ohlsson, Ingrid Ljungvall, Jens Häggström, Brittany Vester Boler, Pascal Steiner, Sharlene Day, Calum A. MacRae, Mark A. Oyama   +12 more
wiley   +1 more source

Developmental roles for the serotonin transporter

, 2010
From invertebrates to humans, serotonin (5-HT) exerts structural effects especially during development. The 5-HT transporter (SERT) directly regulates these effects by maintaining extracellular 5-HT concentrations within a physiological range and ...
Persico A. M., Antonio M. Persico
core   +1 more source

Association analysis of serotonin transporter gene polymorphism among the South-Indian migraineurs. [PDF]

Curr J Neurol, 2023
Kesavan P, Satheesh AP, Rasheed AHRS, Veerappan U, Kannaian S, Veerabathiran R.   +5 more
europepmc   +1 more source

Acute effects of anti‐seizure medications on network level dynamics: A systematic comparison using multielectrode arrays

Epilepsia, EarlyView.
Abstract Objective A multi‐electrode array (MEA) is a powerful extracellular recording technique for long‐term monitoring of neuronal network activity. In recent years, MEA‐based assays have been applied increasingly to evaluate drug efficacy and neurotoxicity, including the assessment of anti‐seizure medications (ASMs). However, systematic comparisons
Griselda Marku, Lena Gschossmann, Kerstin Hallmann, Heinz Beck, Kunihiko Araki   +4 more
wiley   +1 more source

Affective-related endophenotypes in serotonin transporter over-expressing mice [PDF]

, 2008
The affective disorders (anxiety and depression) are common psychiatric disorders that primarily involve disturbances in mood and represent the second leading source of disease burden world-wide.
Dawson, Neil
core  

Contribution of gene-modified mice and rats to our understanding of the cardiovascular pharmacology of serotonin

, 2010
International audienceThis review focuses on new insights provided by gene-modified animals into the cardiovascular pharmacology of serotonin. During their development, mice mutant for tryptophan hydroxylase 1 and lacking peripheral serotonin, or mutant ...
Tarak Ayadi, Laurent Monassier, Luc Maroteaux, Monassier, Laurent, Ayadi, Tarak, Maroteaux, Luc, Marc André Laplante, Stéphane Doly, Laplante, Marc André, Doly, Stéphane   +9 more
core   +1 more source

Brain gain-Is the cognitive performance of domestic hens affected by a functional polymorphism in the serotonin transporter gene? [PDF]

Front Psychol, 2022
Dudde A, Phi Van L, Schrader L, Obert AJ, Krause ET.   +4 more
europepmc   +1 more source

Gut‐microbiota‐brain Axis and post‐traumatic epilepsy

Epilepsia Open, EarlyView.
Abstract There has been growing evidence that perturbations in gut‐microbiota‐brain axis (GMBA) are involved in mechanisms of chronic sequelae of traumatic brain injury (TBI). This review discusses the connection between GMBA and post‐traumatic epilepsy (PTE), the latter being a common outcome of TBI.
Andrey Mazarati
wiley   +1 more source

Association between a genetic variant in the serotonin transporter gene (SLC6A4) and suicidal behavior in patients with schizophrenia

Behavioral and Brain Functions, 2012
Background The serotonin (5-hydroxytryptamin; 5-HT) system has a central role in the circuitry of cognition and emotions. Multiple lines of evidence suggest that genetic variation in the serotonin transporter gene (SLC6A4; 5-HTT) is associated with ...
Lindholm Carlström Eva, Saetre Peter, Rosengren Anders, Thygesen Johan H, Djurovic Srdjan, Melle Ingrid, Andreassen Ole A, Werge Thomas, Agartz Ingrid, Hall Håkan, Terenius Lars, Jönsson Erik G   +11 more
doaj   +1 more source

Phenotypic correlates of the serotonin transporter gene [PDF]

Acta Neuropsychiatrica, 2006
A, Finch, K, Baikie, P, Mitchell, G, Parker, J, Reddy, P R, Schofield, T, Showyin, J, Siegel, L, Wedgwood, K, Wilhelm   +9 more
openaire   +2 more sources