Results 101 to 110 of about 2,926,392 (292)

Pharmacology of amphetamine-type designer drugs [PDF]

, 2013
In this thesis project, we studied the pharmacology of long-known psychostimulants and of novel amphetamine-type designer drugs in vitro. On the basis of the pharmacological characterization, we focused on the drug effects in humans, investigating the ...
Simmler, Linda
core   +1 more source

Associations of the serotonin transporter gene polymorphism, 5-HTTLPR, and adverse life events with late life depression in the elderly Lithuanian population. [PDF]

Sci Rep, 2023
Simonyte S, Grabauskyte I, Macijauskiene J, Lesauskaite V, Lesauskaite V, Kvaal KS, Stewart R.   +6 more
europepmc   +1 more source

Inherited metabolic epilepsies–established diseases, new approaches

Epilepsia Open, EarlyView.
Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley   +1 more source

Addressing the serotonin hypothesis of depression through analyses of genetics, methylation and metabolite variations in glioma patients

Scientific Reports
Serotonin and serotonin metabolism has for decades been understood as playing a critical role in mood disorders and has more recently also been implicated in brain tumour biology.
Wendy Yi-Ying Wu, Beatrice Melin, Benny Björkblom, Rickard L. Sjöberg   +3 more
doaj   +1 more source

Ketogenic diet for infantile epileptic spasms

Epilepsia Open, EarlyView.
Abstract Approximately half of all cases of Infantile Epileptic Spasms Syndrome (IESS) do not respond to vigabatrin and hormonal therapies. There is no clear consensus as to the second‐line therapy for IESS. Ketogenic diet (KD) has emerged as an effective treatment for certain drug‐resistant epilepsies and in many cases of IESS.
Morris H. Scantlebury, Anamika Choudhary, Andy Cheuk‐Him Ng, Cezar Gavrilovici   +3 more
wiley   +1 more source

Serotonin transporter genotype, morning cortisol and subsequent depression in adolescents

, 2009
The short (s) allele of the serotonin transporter gene promoter (5-HTTLPR) may be associated with exposure to social adversities and the subsequent onset of depressive illness in ...
Herbert, Joe, Goodyer, Ian M., Ban, Maria, Bacon, Alison, Croudace, Tim; id_orcid   +4 more
core   +1 more source

Hypermethylation of the serotonin transporter gene and paternal parenting styles in untreated anorexia nervosa patients: A pilot study. [PDF]

Heliyon, 2023
He Q, Lian C, Peng S, Chen H, Kang Q, Chen J.   +5 more
europepmc   +1 more source

The gut microbiome and drug‐resistant epilepsy: Microbiome–antiseizure medication interactions and implications for pharmacoresistance

Epilepsia Open, EarlyView.
Abstract Drug‐resistant epilepsy (DRE) affects approximately one‐third of patients with epilepsy and represents a major unmet clinical need. While traditional hypotheses of pharmacoresistance have focused on alterations in drug targets, efflux transporter overexpression, and intrinsic disease severity, the gut microbiome has recently emerged as a ...
Khaled Zammar, Majd A. AbuAlrob, Musab Ali, Simona Lattanzi, Boulenouar Mesraoua   +4 more
wiley   +1 more source

The study of genetic polymorphisms related to serotonin in Alzheimer's disease: a new perspective in a heterogenic disorder

Brazilian Journal of Medical and Biological Research, 1999
Genetic and environmental factors have been implicated in the development of Alzheimer's disease (AD), the most common form of dementia in the elderly. Mutations in 3 genes mapped on chromosomes 21, 14 and 1 are related to the rare early onset forms of ...
Oliveira J.R.M., Zatz M.
doaj  

Parenting and the Serotonin Transporter Gene (5HTTLPR), Is There an Association? A Systematic Review of the Literature. [PDF]

Int J Environ Res Public Health, 2022
Landoni M, Dalla Muta A, Di Tella S, Ciuffo G, Di Blasio P, Ionio C.   +5 more
europepmc   +1 more source