Results 121 to 130 of about 2,926,392 (292)

No association between peripheral serotonin-gene-related DNA methylation and brain serotonin neurotransmission in the healthy and depressed state

Clinical Epigenetics
Background Methylation of serotonin-related genes has been proposed as a plausible gene-by-environment link which may mediate environmental stress, depressive and anxiety symptoms.
S. E. P. Bruzzone, B. Ozenne, P. M. Fisher, G. Ortega, P. S. Jensen, V. H. Dam, C. Svarer, G. M. Knudsen, K. P. Lesch, V. G. Frokjaer   +9 more
doaj   +1 more source

Exploring the Structural and Functional Effects of Nonsynonymous SNPs in the Human Serotonin Transporter Gene Through <i>In Silico</i> Approaches. [PDF]

Bioinform Biol Insights, 2022
Mia MA, Uddin MN, Akter Y, Jesmin, Wal Marzan L.   +4 more
europepmc   +1 more source

Analysis of the serotonin transporter promoter rs25531 polymorphism in premenstrual dysphoric disorder

, 2010
The objective of this study was to investigate whether the functional rs25531 promoter polymorphism in the serotonin transporter gene is associated with premenstrual dysphoric ...
El-Shourbagy, Maged, Ismail, Khaled M K, O'Brien, Shaughn, Magnay, Julia L, Fryer, Anthony A, Maged El-Shourbagy, Julia L. Magnay, Shaughn O'Brien, Khaled M.K. Ismail, Anthony A. Fryer   +9 more
core   +1 more source

Sudden infant death syndrome revisited: serotonin transporter gene, polymorphisms and promoter methylation. [PDF]

Pediatr Res, 2022
Pfisterer N, Meyer-Bockenkamp F, Qu D, Preuss V, Rothämel T, Geisenberger D, Läer K, Vennemann B, Albers A, Engelmann TA, Frieling H, Rhein M, Klintschar M.   +12 more
europepmc   +1 more source

Apathy in Lewy Body Disorders: A Position Paper

Movement Disorders, EarlyView.
Abstract Apathy is one of the most prevalent and disabling non‐motor symptoms in Parkinson's disease (PD) and dementia with Lewy bodies (DLB), collectively referred to as Lewy body disorders (LBDs). It is associated with reduced quality of life, accelerated cognitive decline, increased caregiver burden, and poorer functional outcomes, yet remains ...
Jaime Kulisevsky, Lidia Bojtos, Milica G. Kramberger, Elisa Mantovani, Iulia Murasan, Jose‐Alberto Palma, Karolina Poplawska‐Domaszewicz, Anna Sauerbier, Kallol Ray Chaudhuri, Per Odin, Daniel Weintraub, Anette Schrag, Cristian Falup‐Pecorariu   +12 more
wiley   +1 more source

NO ASSOCIATION BETWEEN POLYMORPHISMS IN FOUR SEROTONIN RECEPTOR GENES, SEROTONIN TRANSPORTER GENE AND ALCOHOL-RELATED SUICIDE [PDF]

, 2010
Background: Serotonin (5-HT) is an important neurotransmitter with wide-ranging functions. Its disfunction in the central nervous system seems to play an important role in many psychiatric disorders and suicidal behavior.
Pregelj, Peter, Komel, Radovan, Videtič Paska, Alja, TomorTomori, Martina, Zupanc, Tomaž   +4 more
core   +1 more source

Histone deacetylase HDAC1 downregulates transcription of the serotonin transporter (5-HTT) gene in tumor cells

, 2015
Serotonin (5-HT) has been reported to be involved in cancer progression by stimulating angiogenesis and cell growth. In this study, we examined the expression of the serotonin transporter (5-HTT) and the role of histone deacetylases (HDACs) in regulating
Mühlbauer, E., Phi van, D. K., Phi-van, Loc   +2 more
core   +1 more source

The serotonin transporter gene and female personality variation in a free-living passerine. [PDF]

Sci Rep, 2021
Thys B, Grunst AS, Staes N, Pinxten R, Eens M, Grunst ML.   +5 more
europepmc   +1 more source

Repurposing antimicrobial agents for neuroprotection: Mechanisms, clinical potential, and challenges

Neuroprotection, EarlyView.
Antimicrobial agents exert neuroprotective effects through modulation of interconnected pathways. Tetracyclines, macrolides, antimalarial agents, sulfones, and antiparasitic agents suppress neuroinflammation, oxidative stress, and apoptosis while preserving mitochondrial function and neurotransmission.
Mohammad Amin Manavi, Mohammadreza Salehi, Razieh Mohammad Jafari, Ramin Goudarzi, Saman Khosravi, Ahmad Reza Dehpour   +5 more
wiley   +1 more source

Impact of serotonin transporter gene polymorphism on gut motility in patients with type 2 Diabetes mellitus. [PDF]

J Neurogastroenterol Motil, 2021
Malik A, Saha S, Morya RK, Bhadada SK, Rana SV.   +4 more
europepmc   +1 more source