Results 91 to 100 of about 25,164 (313)

The effect of selective serotonin re‐uptake inhibitors on the risk of myocardial infarction in a cohort of patients with depression [PDF]

, 2011
Stephen E. Kimmel, Hedi Schelleman, Jesse A. Berlin, David W. Oslin, Rachel Weinstein, Judith L. Kinman, William H. Sauer, James D. Lewis   +7 more
openalex   +1 more source

Host–microbiota interaction drives 5‐hydroxyindole‐3‐acetic acid production to promote linear growth in infant mice

iMetaOmics, EarlyView.
This study discovered that Lactiplantibacillus plantarum Hi188 promoted linear growth in postweaning mice. Transcriptomic analysis, untargeted metabolomics, and in vitro experiments showed that the elevated levels of 5‐hydroxyindole‐3‐acetic acid (5‐HIAA) activated the hepatic aryl hydrocarbon receptor (AhR) and subsequently promoted insulin‐like ...
Yongmei Yang, Jing Yang, Weiyao Zhang, Linghao Zhou, Chenxu Zhu, Xuguang Zhang, Yuejian Mao, Meiling Zhang   +7 more
wiley   +1 more source

Further Studies on Conformationally Constrained Tricyclic Tropane Analogues and Their Uptake Inhibition at Monoamine Transporter Sites:  Synthesis of (Z)-9-(Substituted arylmethylene)-7-azatricyclo[4.3.1.0^3,7]decanes as a Novel Class of Serotonin Transporter Inhibitors

, 2002
Ao Zhang, Guo‐Chun Zhou, Alexander Hoepping, Jayanta K. Mukhopadhyaya, Kenneth M. Johnson, Mei Zhang, Alan P. Kozikowski   +6 more
openalex   +1 more source

Weizmannia coagulans XY2 Mitigates Copper Neurotoxicity via Gut–Brain Axis Modulation of Tryptophan Metabolism and Oxidative‐Inflammatory Crosstalk

iMetaOmics, EarlyView.
Copper interferes with tryptophan metabolism and 5‐HT levels by modulating intestinal flora. Intestinal barrier breakdown and inflammatory response trigger nerve damage under copper exposure. W. coagulans XY2 alleviates copper‐induced neurotoxicity by targeting a multi‐dimensional “tryptophan metabolism‐antioxidant defense‐gut‐brain axis” network.
Yufang Gao, Xiaodong Zheng, Fujie Yan
wiley   +1 more source

BindingDB Entry 4719: Affinities of fluoxetine, its enantiomers, and other inhibitors of serotonin uptake for subtypes of serotonin receptors.

, 2011
Wong Dt
openalex   +1 more source

White Matter Dysfunction and Neurotransmitter Basis Underlying the Freezing of Gait in Parkinson's Disease

iNew Medicine, EarlyView.
In the freezing of gait in Parkinson's disease, white matter shows decreased local activity but increased functional connectivity. These distinct dysfunctions are uniquely associated with specific neurotransmitter systems (GABA, dopamine, etc.), mapping a new neurochemical basis for this debilitating symptom. ABSTRACT Freezing of gait (FOG) is a severe
Pingping Liu, Jinmei Sun, Lili Hu, Xin Chen, Jinying Han, Liuzhenxiong Yu, Siyu Fan, Rong Ye, Kai Wang, Gong‐Jun Ji, Panpan Hu   +10 more
wiley   +1 more source

BDNF Level in the Rat Prefrontal Cortex Increases Following Chronic but Not Acute Treatment with Duloxetine, a Dual Acting Inhibitor of Noradrenaline and Serotonin Re-uptake

, 2008
Claudio Mannari, Nicola Origlia, Alessia Scatena, Alessandro Del Debbio, Mario Catena, Grazia Dell’Agnello, Alessandra Barraco, Luca Giovannini, Liliana Dell’Osso, Luciano Domenici, Armando Piccinni   +10 more
openalex   +2 more sources

Norfluoxetine Enantiomers as Inhibitors of Serotonin Uptake in Rat Brain [PDF]

, 1993
David T. Wong, Frank P. Bymaster, Leroy R. Reid, Douglas A. Mayle, Joseph H. Krushinski, David W. Robertson   +5 more
openalex   +1 more source

Reduced prevalence of periodontitis in antidepressant users: Findings from a large‐scale US sample

Journal of Periodontology, EarlyView.
Abstract Background Periodontitis and major depression disorder have been shown to have a bidirectional association. However, the impact of antidepressants, the primary pharmacological treatment for depression, on periodontal health remains unclear.
María Martínez, David Fraguas, Elena Figuero, Francesco D´Aiuto   +3 more
wiley   +1 more source

Assessing the Neurodevelopmental Impact of Fluoxetine, Citalopram, and Paroxetine on Neural Stem Cell-Derived Neurons

Pharmaceuticals
Background/Objectives: Many pregnant women globally suffer from depression and are routinely prescribed selective serotonin reuptake inhibitors (SSRIs). These drugs function by blocking the re-uptake of serotonin by the serotonin transporter (SERT) into ...
Kimia Hosseini, Andrea Cediel-Ulloa, Mohamed H. AL-Sabri, Anna Forsby, Robert Fredriksson   +4 more
doaj   +1 more source