Identification of potentially causative drugs associated with hypotension: A scoping review
Antihypertensives are just the tip of the iceberg of drugs that cause hypotension. This scoping review examines antihypertensive and nonantihypertensive drugs associated with hypotension, analysing 97 studies from 2013 to 2023. It examines the frequency of reporting and corresponding levels of evidence and evaluates the results taking into account ...
Nurunnisa Sari +2 more
wiley +1 more source
Antidepressivos e suicídio nos adolescentes.
In recent years, drug regulation agencies from the US and the UK have issued warnings concerning the emergence of suicidal behavior in children and adolescents treated with antidepressants.
Manuela Silva, Daniel Sampaio
doaj +1 more source
Het gebruik van psychofarmaca bij verenplukkende papegaaien [PDF]
Feather damaging behavior is a common problem in captive parrots (Psittaciformes). Besides medical indications, socio-environmental and neurobiologic causes may underlie the behavior, in which case it is often referred to as psychogenic feather picking ...
Antonissen, Gunther +3 more
core +1 more source
Acute physical exercise improves shifting in adolescents at school: evidence for a dopaminergic contribution [PDF]
The executive function of shifting between mental sets demands cognitive flexibility. Based on evidence that physical exercise fostered cognition, we tested whether acute physical exercise can improve shifting in an unselected sample of adolescents ...
Barenberg, J. (Jonathan) +8 more
core +2 more sources
Bivalent and bitopic ligands of the opioid receptors: The prospects of a dual approach
Abstract Opioid receptors belonging to the class A G‐protein coupled receptors (GPCRs) are the targets of choice in the treatment of acute and chronic pain. However, their on‐target side effects such as respiratory depression, tolerance and addiction have led to the advent of the ‘opioid crisis’.
Marie Emilie Hovah, Ulrike Holzgrabe
wiley +1 more source
Possible mechanisms underlying wheel-running-induced hypotensive effects
Physical activity of moderate intensity, like walking and jogging, can reduce the risk of developing metabolic syndrome and improve hypertension. However, such anti-hypertensive effects have yet to be fully studied.
Susumu Sakata +2 more
doaj +1 more source
The role of serotonin in depression—A historical roundup and future directions
Although depression has been studied for many decades, the exact mechanisms that lead to depression are still unknown, and available treatments only help a fraction of patients. In the 1960s, the serotonin hypothesis was published, suggesting that serotonin is the key player in depression. However, this hypothesis is being increasingly doubted. In this
Svenja Bremshey +3 more
wiley +1 more source
The challenge of perioperative pain management in opioid-tolerant patients [PDF]
The increasing number of opioid users among chronic pain patients, and opioid abusers among the general population, makes perioperative pain management challenging for health care professionals.
Bifulco, F +9 more
core +2 more sources
Does vitamin D supplementation impact serotonin levels? A systematic review and meta‐analysis
Abstract Background and Aims Vitamin D deficiency impacts a significant proportion of the world's population, and this deficiency has been linked to various conditions characterized by imbalanced serotonin regulation. The objective of this systematic review and meta‐analysis was to evaluate the effect of vitamin D supplementation on serum serotonin ...
Malek Alimohammadi‐Kamalabadi +11 more
wiley +1 more source
Transcriptional evidence for the role of chronic venlafaxine treatment in neurotrophic signaling and neuroplasticity including also Glutamatergic [corrected] - and insulin-mediated neuronal processes. [PDF]
Venlafaxine (VLX), a serotonine-noradrenaline reuptake inhibitor, is one of the most commonly used antidepressant drugs in clinical practice for the treatment of major depressive disorder (MDD).
Viola Tamási +7 more
doaj +1 more source

