Results 31 to 40 of about 54,993 (303)

Evaluation of a Proteus rettgeri O-serotyping system for epidemiological investigation [PDF]

Journal of Clinical Microbiology, 1976
An evaluation of the serotyping system for Proteus rettgeri has been performed through its application to 561 human isolates of this species. Of these, 545 were typable and could be separated into 58 O serotypes. A group of isolates from one hospital, and clinically implicated in cross-infections, was found to belong the same O serotype, confirming the
J L, Penner, N A, Hinton, J N, Hennessy
openaire   +2 more sources

The impact of specific and non-specific immunity on the ecology of Streptococcus pneumoniae and the implications for vaccination. [PDF]

, 2013
More than 90 capsular serotypes of Streptococcus pneumoniae coexist despite competing for nasopharyngeal carriage and a gradient in fitness. The underlying mechanisms for this are poorly understood and make assessment of the likely population impact of ...
Robertson, Charles, Edmunds, W. John, Flasche, Stefan, Goldblatt, David, Yoon Hong, Choi, Choi, Yoon Hong, Edmunds, W John, Miller, Elizabeth, Robertson, Chris   +8 more
core   +1 more source

Adeno‐associated virus serotype 2 capsid variants for improved liver‐directed gene therapy

Hepatology, EarlyView., 2022
Abstract Background and Aims Current liver‐directed gene therapies look for adeno‐associated virus (AAV) vectors with improved efficacy. With this background, capsid engineering is explored. Whereas shuffled capsid library screenings have resulted in potent liver targeting variants with one first vector in human clinical trials, modifying natural ...
Nadja Meumann, Marti Cabanes‐Creus, Moritz Ertelt, Renina Gale Navarro, Julie Lucifora, Qinggong Yuan, Karin Nien‐Huber, Ahmed Abdelrahman, Xuan‐Khang Vu, Liang Zhang, Ann‐Christin Franke, Christian Schmithals, Albrecht Piiper, Annabelle Vogt, Maria Gonzalez‐Carmona, Jochen T. Frueh, Evelyn Ullrich, Philip Meuleman, Steven R. Talbot, Margarete Odenthal, Michael Ott, Erhard Seifried, Clara T. Schoeder, Joachim Schwäble, Leszek Lisowski, Hildegard Büning   +25 more
wiley   +1 more source

O‐Linked GlcNAc in serotype‐2 adenovirus fibre [PDF]

European Journal of Biochemistry, 1989
Serotype‐2 adenovirus fibre is shown to possess an O‐linked GlcNAc residue and to have affinity for wheat germ agglutinin. The cytoplasmic and nuclear fibres are both glycosylated. Glycosylation seems to take place in the cytoplasm since most of the [14C]GlcN‐labelled fibre is found in this compartment, little label being associated with the microsomes.
M L, Caillet-Boudin, G, Strecker, J C, Michalski   +2 more
openaire   +2 more sources

Spatial pattern of foot-and-mouth disease virus serotypes in North Central Nigeria [PDF]

Veterinary World, 2017
Aim: This study aimed to determine the foot-and-mouth disease virus (FMDV) serotypes circulating, the prevalence of FMDV serotypes, and the spatial distribution of FMDV among sedentary and pastoral cattle herds in the North-Central Nigeria.
Yiltawe Simwal Wungak, Olayinka O. Ishola, Babasola O. Olugasa, David D. Lazarus, David O. Ehizibolo, Hussaini G. Ularamu   +5 more
doaj   +1 more source

Comparative phylogenomics of Streptococcus pneumoniae isolated from invasive disease and nasopharyngeal carriage from West Africans. [PDF]

, 2012
BACKGROUND: We applied comparative phylogenomics (whole genome comparisons of microbes using DNA microarrays combined with Bayesian-based phylogenies) to investigate S.
Hinds Jason, Eric S Donkor, Donkor, ES, Martin Antonio, Stabler Richard A, Wren, BW, Hinds, Jason, Wren, Brendan W, Antonio Martin, Adegbola Richard A, Hinds, J, Antonio, M, Donkor Eric S, Wren Brendan W, Richard A Stabler, Jason Hinds, Adegbola, Richard A, Stabler, RA, Stabler, Richard A, Adegbola, RA, Donkor, Eric S, Antonio, Martin, Richard A Adegbola, Brendan W Wren   +23 more
core   +1 more source

Molecular matching of circulating foot and mouth disease viruses and vaccinal strains in Egypt, 2016-2019. [PDF]

Benha Veterinary Medical Journal, 2020
Regardless mass vaccination programs in Egypt with inactivated polyvalent vaccines of FMDvirus. FMD virus is still persistent with major economic burden.
Nehal Shahen, zeinab aboezz, Ayman Elhabba, Naglaa Hagaa, Saad Sharawi   +4 more
doaj   +1 more source

Identification of critical residues of O-antigen-modifying O-acetyltransferase B (OacB) of Shigella flexneri

BMC Molecular and Cell Biology, 2022
Background Shigellosis is an acute gastrointestinal disease caused primarily by the bacterium Shigella flexneri. Upon ingestion, S. flexneri initiates a serotype-specific immune response that targets the O-antigen of the pathogen’s lipopolysaccharide.
Munazza I. Rajput, Naresh K. Verma
doaj   +1 more source

Cross-Serotype Reactivity of ELISAs Used to Detect Antibodies to the Structural Proteins of Foot-and-Mouth Disease Virus

Viruses, 2022
Antibodies to the foot-and-mouth disease virus (FMDV) capsid induced by infection or vaccination can provide serotype-specific protection and be measured using virus neutralization tests and viral structural-protein (SP-)ELISAs. Separate tests are needed
Anna B. Ludi, Alison Morris, Simon Gubbins, Amin Asfor, Madeeha Afzal, Clare F. Browning, Santina Grazioli, Efrem Alessandro Foglia, Ginette Wilsden, Alison Burman, Emiliana Brocchi, David J. Paton, Donald P. King   +12 more
doaj   +1 more source

Variation at the capsule locus, cps, of mistyped and non-typable Streptococcus pneumoniae isolates. [PDF]

, 2012
Contains fulltext : 110162.pdf (Publisher’s version ) (Closed access)The capsule polysaccharide locus (cps) is the site of the capsule biosynthesis gene cluster in encapsulated Streptococcus pneumoniae. A set of pneumococcal samples and
Bentley, S.D., Hinds, J., Lambertsen, L., Bootsma, H. J., Hermans, PW, Bentley, SD, Hanage, WP, Antonio, M., Hermans, P.W.M., O'Brien, K. L., Turner, P, Hanage, William, Antonio, M, Salter, S. J., Bentley, S. D., Hermans, P. W. M., Gould, KA, Turner, P., Gould, K.A., Bootsma, H.J., Turner, Paul, Gould, K. A., O'Brien, KL, Salter, S.J., Salter, SJ, Bootsma, HJ, Lambertsen, L, Hinds, J, O'Brien, K.L., Hanage, W.P.   +29 more
core   +1 more source