Results 121 to 130 of about 115,869 (313)

Potent monoclonal antibodies against multidrug‐resistant hypervirulent Klebsiella pneumoniae

Interdisciplinary Medicine, EarlyView.
A novel immunization strategy using a low‐virulence, multidrug‐resistant strain yields synergistic monoclonal antibodies against hypervirulent Klebsiella pneumoniae. These antibodies provide cross‐serotype protection through a dual‐mechanism of pathogen clearance and immunomodulation, offering a promising non‐antibiotic therapeutic for resistant ...
Yushan Jiang, Zhuolin Li, Yang Yang, Zihan He, Tyuji Hoshino, Vladislav Victorovich Khrustalev, Qing Zhu, Weiling Wu, Wei Zhao, Chenguang Shen, Shi Ouyang   +10 more
wiley   +1 more source

Multi‐omics biomarkers for intestinal infection and inflammation in inflammatory bowel disease: Current evidence, translational challenges, and diagnostic opportunities

Interdisciplinary Medicine, EarlyView.
Prospective multi‐site cohorts, multi‐omics profiling, and computational analysis may help identify biomarker patterns across clinical settings in IBD and superimposed infections. With further mechanistic and clinical validation, these signals could support the development of practical multi‐analyte tools for more precise diagnosis and management ...
Ziyu Yang, Jiayi Yao, Xinxian Zhao, Yan Xu, Yifan Chen, Tianchi Chen, Ying Jian, Min Li   +7 more
wiley   +1 more source

Anti‐inflammatory and cytotoxic properties of kānuka (Kunzea ericoides) subcritical water extract

Journal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKGROUND Kānuka (Kunzea ericoides) is a medicinal plant native to New Zealand with numerous therapeutic benefits due to its rich bioactive profile. Although several in vitro studies have shown promising anti‐inflammatory activity, substantial evidence elucidating its underlying inflammatory regulatory mechanism and evaluating its cytotoxic ...
Indhuja Devadass, Simon Swift, Saeid Baroutian   +2 more
wiley   +1 more source

Trends in hospitalizations for vaccine‐preventable diseases in the United States from 2014 to 2024

Journal of Hospital Medicine, EarlyView.
Abstract Background and Objectives Vaccination rates have declined in recent years, resulting in outbreaks of vaccine‐preventable diseases (VPDs) among children. We aimed to evaluate VPD hospitalization rates from 2014 to 2024 and to report associated trends in outcomes including intensive care utilization, mortality, readmissions, and costs.
Nathan M. Money, Erin Sullivan, Hannah Rector, Corrie E. McDaniel, Jessica L. Markham, Mersine A. Bryan   +5 more
wiley   +1 more source

Periodontal microbiology and microbial etiology of periodontal diseases: Historical concepts and contemporary perspectives

Periodontology 2000, EarlyView., 2023
Abstract This narrative review summarizes the collective knowledge on periodontal microbiology, through a historical timeline that highlights the European contribution in the global field. The etiological concepts on periodontal disease culminate to the ecological plaque hypothesis and its dysbiosis‐centered interpretation.
Georgios N. Belibasakis, Daniel Belstrøm, Sigrun Eick, Ulvi K. Gursoy, Anders Johansson, Eija Könönen   +5 more
wiley   +1 more source

Community acquired pneumonia among pediatric outpatients in Salvador, Northeast Brazil, with emphasis on the role of pneumococcus

Brazilian Journal of Infectious Diseases, 2001
Pneumonia is one of the leading causes of hospitalization and death among children in developing countries, and mortality due to pneumonia has been associated with S. pneumoniae infection.
Nascimento-Carvalho Cristiana M.C., Lopes Antônio A., Gomes Maria Daniela B.S., Magalhães Morgana P., Oliveira Juliana R., Vilas-Boas Ana Luisa, Ferracuti Roberta, Brandileone Maria Cristina C., Guerra Maria Luiza L.S., Alves Noraney N., Athayde Ledilce A., Caldas Renilza M., Barberino Maria Goreth M. A., Duarte Jussara, Brandão Maria Angélica S., Rocha Heonir, Benguigui Yehuda, Di Fabio José Luis   +17 more
doaj  

Population structure of Australian isolates of Streptococcus suis

, 1993
The genetic diversity of 109 isolates of Streptococcus suis, which were recovered mainly from Australian pigs, was examined by multilocus enzyme electrophoresis. The collection was genetically diverse.
Robertson, I.D., Hampson, D.J., Clarke, I.L., Trott, D.J., Mwaniki, C.G.   +4 more
core  

Does timing of systemic antibiotics influence periodontal treatment outcomes? A randomized clinical trial

Journal of Periodontology, EarlyView.
Abstract Background The aim of this study is to determine whether the timing of metronidazole (MTZ) and amoxicillin (AMX) administration, relative to scaling and root planing (SRP), influences the clinical and microbiological outcomes of periodontal treatment.
Daiane Fermiano, Eduardo de Souza Oliveira, Maria Josefa Mestnik, Luciene C. Figueiredo, Takahiko Shiba, Shunsuke Matsumura, Edson de Sousa, Helio Doyle, Rafael Oliveira Dias, Marcelo de Faveri, Magda Feres   +10 more
wiley   +1 more source

Prevalence and antimicrobial susceptibility of Salmonella serotypes in patients from Ribeirão Preto, São Paulo, Brazil, between 1985 and 1999

Brazilian Journal of Infectious Diseases, 2002
Salmonella strains isolated from 1,138 samples representing 28,199 biological materials (stool, urine, blood and other fluids), collected between January 1985 and January 1999 at a reference University Hospital in Ribeirão Preto, São Paulo, Brazil, were ...
Castro Fabíola Attié de, Santos Vanda Roseli dos, Martins Carlos H. Gomes, Fernandes Sueli A., Zaia José Eduardo, Martinez Roberto   +5 more
doaj  

Dengue Hemorrhagic Fever in Quang Nam Province (Vietnam) from 2020 to 2022—A Study on Serotypes Distribution and Immunology Factors

Diagnostics
Background: Dengue hemorrhagic fever (DHF) is the most prevalent and fastest-growing vector-borne disease globally, with symptoms ranging from mild to severe and, in some cases, fatal.
Huong T. Pham, Thao N. T. Pham, Nhu H. T. Tran, Quang D. Ha, Duy K. Tran, Nam H. D. Nguyen, Van H. Pham, Son T. Pham   +7 more
doaj   +1 more source