Results 81 to 90 of about 135,623 (345)

Rational Design of Inner Ear Drug Delivery Systems

Advanced Science, EarlyView.
Hearing loss is a common disease affecting many people, and inner ear lesions are one of the most important causes. This review focuses on the treatment of inner ear hearing loss by drug delivery systems. It includes the current methods and technologies developed, and it predicts possible directions.
Xiayidan Maimaitikelimu, Zhiyan Xuan, Haoyu Ren, Keng Chen, Hui Zhang, Huan Wang   +5 more
wiley   +1 more source

Multilocus Sequence Typing as a Replacement for Serotyping in Salmonella enterica

PLoS Pathogens, 2012
Salmonella enterica subspecies enterica is traditionally subdivided into serovars by serological and nutritional characteristics. We used Multilocus Sequence Typing (MLST) to assign 4,257 isolates from 554 serovars to 1092 sequence types (STs).
M. Achtman, J. Wain, F. Weill, S. Nair, Zhemin Zhou, V. Sangal, M. Krauland, James Hale, H. Harbottle, A. Uesbeck, G. Dougan, L. Harrison, S. Brisse   +12 more
semanticscholar   +1 more source

A previously undescribed Salmonella serotype: S. sp. serotype rideau [PDF]

International Journal of Systematic Bacteriology, 1967
SUMMARY A new Salmonella serotype (1, 3, 19; fg:-) was described and the designation S. sp. serotype rideau was assigned to it. The culture was isolated in the routine screening of military personnel from Tanzania recently arrived in Canada for special training.
Joseph A. Yurack, Rhoda M. Laidley, Walter C. Harris   +2 more
openaire   +2 more sources

Chronic Psychological Stress Induces Cardiomyocyte Hypertrophy Through Corticosterone‐Glucocorticoid Receptor‐LAMA5 Axis

Advanced Science, EarlyView.
In vivo experiments suggest that cardiomyocyte hypertrophy is an early manifestation of cardiac pathological changes induced by chronic psychological stress. In vivo and in vitro experiments suggest that the corticosterone‐glucocorticoid receptor‐LAMA5 axis mediates cardiomyocyte hypertrophy induced by chronic psychological stress. The clinical results
Chuanjing Zhang, Yongfei Song, Xiaojun Jin, Qingbo Xu, Honghua Ye, Zhuonan Wu, Hui Lin, Jiale Hu, Chen Huang, Jianqing Zhou, Jiangfang Lian   +10 more
wiley   +1 more source

Capsular Serotyping of Streptococcus pneumoniae Using the Quellung Reaction

Journal of Visualized Experiments, 2014
There are over 90 different capsular serotypes of Streptococcus pneumoniae (the pneumococcus). As well as being a tool for understanding pneumococcal epidemiology, capsular serotyping can provide useful information for vaccine efficacy and impact studies.
Maha Habib, Barbara D. Porter, C. Satzke
semanticscholar   +1 more source

Serotype specificity and immunogenicity of the capsular polymer of Haemophilus pleuropneumoniae serotype 5 [PDF]

Infection and Immunity, 1987
Serotyping of Haemophilus pleuropneumoniae and serologic assays for detection of serotype-specific antibody are problematic due to the potential cross-reactivity of the crude antigens used for raising immune serum or for serology. The capsular polymer (CP) of H.
B Mathison, Thomas J. Inzana
openaire   +3 more sources

PSMD14 Stabilizes SLC7A11 to Ameliorate Glucocorticoid‐Induced Osteoporosis by Suppressing Osteocyte Ferroptosis

Advanced Science, EarlyView.
Glucocorticoid‐induced osteoporosis (GIOP) triggers osteocyte ferroptosis via SLC7A11 degradation. PSMD14 stabilizes SLC7A11 by counteracting glucocorticoid‐driven ubiquitination, preserving cystine uptake and glutathione synthesis. AAV‐mediated PSMD14 delivery or its agonist Pantethine rescues osteocyte survival and bone loss in GIOP mice.
Yifeng Shi, Qian Tang, Sunren Sheng, Hongyi Jiang, Chen Jin, Chencheng Zhou, Chenglong Xie, Lin Zheng, Di Zhang, Hui Xu, Cong Xu, Haiwei Ma, Guangheng Xiang, Wenfei Ni, Xiaoyun Pan, Lei Yang, Huazi Xu, Yu Qian, Aimin Wu, Xiangyang Wang, Gang Zheng   +20 more
wiley   +1 more source

Streptococcus suis serotyping by a new multiplex PCR.

Journal of Medical Microbiology, 2014
A multiplex PCR was developed to detect all true serotypes of Streptococcus suis. This multiplex PCR was composed of four reaction sets. The first set identified nine serotypes (serotypes 1/2, 1, 2, 3, 7, 9, 11, 14 and 16), the second set identified ...
Anusak Kerdsin, Y. Akeda, Rujirat Hatrongjit, Unchaya Detchawna, T. Sekizaki, S. Hamada, M. Gottschalk, K. Oishi   +7 more
semanticscholar   +1 more source

Construction and Characterization of Adenovirus Serotype 5 Packaged by Serotype 3 Hexon [PDF]

Journal of Virology, 2002
ABSTRACT Adenovirus serotype 5 (Ad5) has great potential for gene therapy applications. A major limitation, however, is the host immune response against Ad5 infection that often prevents the readministration of Ad5 vectors. In this regard, the most abundant capsid protein, hexon, has been implicated as the major target for neutralizing ...
Igor Dmitriev, Toshiro Seki, Minghui Wang, Elena Kashentseva, David T. Curiel, Hongju Wu   +5 more
openaire   +2 more sources

Restoration of SIRT3 Expression in Aged Mice Alleviates UUO‐Induced Renal Fibrosis by Reducing GSK‐3β Hyperacetylation

Advanced Science, EarlyView.
SIRT3 expression is significantly downregulated in the aged kidney, rendering the kidney more vulnerable to fibrotic changes in obstructive nephropathy. By promoting GSK‐3β deacetylation, SIRT3 indirectly inhibits Wnt/β‐catenin signaling, thereby suppressing renal fibrosis.
Jing Wang, Xiang Ren, Huan Lu, Zihao Guo, Xing Li, Yiqun Tian, Yisheng Yin, Zhenliang Qin, Kun Yun, Minglong Wu, Gang Chen, Xiaoyong Zeng   +11 more
wiley   +1 more source