Results 161 to 170 of about 43,231 (331)

Biomarkers in patients with clinical signs of mild cognitive impairment or mild Alzheimer's disease but without amyloid deposits on positron emission tomography: Results from Bio‐Hermes Study participants

open access: yesAlzheimer's &Dementia, Volume 22, Issue 1, January 2026.
Abstract INTRODUCTION Alzheimer's disease (AD) study participants may present with cognitive impairment who do not have brain amyloid deposits (Aβ−). Identifying predictive biomarkers for non‐amyloid‐related CI may provide better screening tests for trials seeking only CI Aβ+ participants and new therapy targets.
Richard C. Mohs   +11 more
wiley   +1 more source

Plasma extracellular vesicles from APOE3 Christchurch carriers display a protective phenotype in early stages of autosomal dominant Alzheimer's disease

open access: yesAlzheimer's &Dementia, Volume 22, Issue 1, January 2026.
Abstract INTRODUCTION The PSEN1E280A mutation causes autosomal dominant Alzheimer's disease (ADAD) with predictable onset, enabling presymptomatic studies. Extracellular vesicles (EVs) are emerging biomarkers of cognitive decline, but their role in early ADAD is unclear.
Lina Pineda‐Lopez   +14 more
wiley   +1 more source

Poxvirus-Encoded Serpins Do Not Prevent Cytolytic T Cell-Mediated Recovery from Primary Infections [PDF]

open access: bronze, 1999
Arno Müllbacher   +3 more
openalex   +1 more source

Progressive myoclonus epilepsy associated with neuroserpin inclusion bodies (neuroserpinosis) [PDF]

open access: yes, 2016
Familial encephalopathy with neuroserpin inclusion bodies (FENIB) is a conformational proteinopathy characterised by neuronal inclusion bodies composed of the serine protease inhibitor (SERPIN), neuroserpin.
Crowther, DC, Lomas, DA, Roussel, BD
core  

Peptides Derived From Reactive Center Loops Inhibit Digestive Trypsin‐Like Enzymes in Lepidopteran Pests

open access: yesArchives of Insect Biochemistry and Physiology, Volume 121, Issue 1, January 2026.
Soybean yield is often reduced by pest attacks. Among these, Anticarsia gemmatalis Hübner (Lepidoptera: Noctuidae) stands out as one of the most important defoliating pests of soybean. Therefore, the development of new bioinsecticides targeting Lepidopteran pests is an urgent need.
Daniel Guimarães Silva Paulo   +13 more
wiley   +1 more source

Serpin-A3 is Associated with Persistent Albuminuria in Adolescents with Secondary Podocytopathy, in a Region with High Prevalence of Chronic Kidney Disease of Unknown Origin [PDF]

open access: diamond, 2023
Leslie P. Zúñiga-Macías   +5 more
openalex   +1 more source

Mechanistic Insights and Therapeutic Potential of Small Nucleolar RNA Host Genes in the Carcinogenesis of Hepatocellular Carcinoma

open access: yesCancer Medicine, Volume 15, Issue 1, January 2026.
ABSTRACT Background Hepatocellular carcinoma (HCC) is one of the major factors endangering human health due to its poor prognosis, resulting from difficulties in early diagnosis and lack of effective treatment measures. Long non‐coding RNAs (lncRNAs), which are RNA molecules that do not translate into proteins, play essential roles in various tumor ...
Jiajia Luo   +2 more
wiley   +1 more source

Human Protein Z as the Second Known Heme‐Binding Protein from the Endogenous Blood Coagulation Inhibitor System

open access: yesChemBioChem, Volume 27, Issue 1, January 2026.
Protein Z is a vitamin K‐dependent anticoagulant with elusive molecular functions. Herein, it is shown that heme binds to protein Z and induces conformational changes. One histidine‐based heme‐binding motif is identified. High heme‐binding affinity and functional effects are demonstrated on protein level. These findings shed new light on the structural
Paula Lindemann, Marie‐T. Hopp
wiley   +1 more source

Home - About - Disclaimer - Privacy