Results 161 to 170 of about 43,231 (331)
Abstract INTRODUCTION Alzheimer's disease (AD) study participants may present with cognitive impairment who do not have brain amyloid deposits (Aβ−). Identifying predictive biomarkers for non‐amyloid‐related CI may provide better screening tests for trials seeking only CI Aβ+ participants and new therapy targets.
Richard C. Mohs +11 more
wiley +1 more source
Abstract INTRODUCTION The PSEN1E280A mutation causes autosomal dominant Alzheimer's disease (ADAD) with predictable onset, enabling presymptomatic studies. Extracellular vesicles (EVs) are emerging biomarkers of cognitive decline, but their role in early ADAD is unclear.
Lina Pineda‐Lopez +14 more
wiley +1 more source
Poxvirus-Encoded Serpins Do Not Prevent Cytolytic T Cell-Mediated Recovery from Primary Infections [PDF]
Arno Müllbacher +3 more
openalex +1 more source
Progressive myoclonus epilepsy associated with neuroserpin inclusion bodies (neuroserpinosis) [PDF]
Familial encephalopathy with neuroserpin inclusion bodies (FENIB) is a conformational proteinopathy characterised by neuronal inclusion bodies composed of the serine protease inhibitor (SERPIN), neuroserpin.
Crowther, DC, Lomas, DA, Roussel, BD
core
Soybean yield is often reduced by pest attacks. Among these, Anticarsia gemmatalis Hübner (Lepidoptera: Noctuidae) stands out as one of the most important defoliating pests of soybean. Therefore, the development of new bioinsecticides targeting Lepidopteran pests is an urgent need.
Daniel Guimarães Silva Paulo +13 more
wiley +1 more source
Serpin-A3 is Associated with Persistent Albuminuria in Adolescents with Secondary Podocytopathy, in a Region with High Prevalence of Chronic Kidney Disease of Unknown Origin [PDF]
Leslie P. Zúñiga-Macías +5 more
openalex +1 more source
ABSTRACT Background Hepatocellular carcinoma (HCC) is one of the major factors endangering human health due to its poor prognosis, resulting from difficulties in early diagnosis and lack of effective treatment measures. Long non‐coding RNAs (lncRNAs), which are RNA molecules that do not translate into proteins, play essential roles in various tumor ...
Jiajia Luo +2 more
wiley +1 more source
Protein Z is a vitamin K‐dependent anticoagulant with elusive molecular functions. Herein, it is shown that heme binds to protein Z and induces conformational changes. One histidine‐based heme‐binding motif is identified. High heme‐binding affinity and functional effects are demonstrated on protein level. These findings shed new light on the structural
Paula Lindemann, Marie‐T. Hopp
wiley +1 more source

