Results 211 to 220 of about 34,502 (251)
Some of the next articles are maybe not open access.
Serpin Polymerization In Vitro
2011Serpin polymerization is an event which generally occurs within living tissue as a consequence of a folding defect caused by point mutations. Major advances in cell biology and imaging have allowed detailed studies into subcellular localization, processing, and clearance of serpin polymers, but to understand the molecular basis of the misfolded state ...
James A, Huntington, Masayuki, Yamasaki
openaire +2 more sources
Maspin: A Tumor Suppressing Serpin
1996Maspin, a serpin found in mammary epithelial cells, has been shown to have tumor suppressor activity. The gene is expressed in normal human mammary epithelial cells but down-regulated in invasive breast carcinomas. Similar patterns of expression at the RNA and protein levels are seen by Northern analysis with cells grown in culture and by ...
R, Sager +3 more
openaire +3 more sources
2013
Serpins (serine proteinase inhibitors) are the largest superfamily of protease inhibitors. The serpins are structurally similar but functionally diverse proteins that fold into a conserved structure and employ a unique suicide substrate-like inhibitory mechanism. Most of them act as classical protease inhibitors, but there are also serpins that inhibit
Czeslaw S. Cierniewski, Joanna Boncela
openaire +1 more source
Serpins (serine proteinase inhibitors) are the largest superfamily of protease inhibitors. The serpins are structurally similar but functionally diverse proteins that fold into a conserved structure and employ a unique suicide substrate-like inhibitory mechanism. Most of them act as classical protease inhibitors, but there are also serpins that inhibit
Czeslaw S. Cierniewski, Joanna Boncela
openaire +1 more source
2015
The serpins are a family of structurally conserved protease inhibitors found mainly in the animal and plant kingdoms. This chapter will focus on the evolution of plant serpins brought to light by mining of the growing number of whole plant genomes. Our analysis shows remarkable diversification of plant serpins as compared to those in animals. Indeed, a
Maja Cohen +2 more
openaire +1 more source
The serpins are a family of structurally conserved protease inhibitors found mainly in the animal and plant kingdoms. This chapter will focus on the evolution of plant serpins brought to light by mining of the growing number of whole plant genomes. Our analysis shows remarkable diversification of plant serpins as compared to those in animals. Indeed, a
Maja Cohen +2 more
openaire +1 more source
Genetic engineering and the serpins
BioEssays, 1988D R, Boswell, R W, Carrell
openaire +2 more sources
Penaeus monodon SERPIN, PmSERPIN6, is implicated in the shrimp innate immunity
Fish and Shellfish Immunology, 2010Kunlaya Somboonwiwat
exaly
A serpin from Chinese shrimp Fenneropenaeus chinensis is responsive to bacteria and WSSV challenge
Fish and Shellfish Immunology, 2009Fuhua Li, Jianhai Xiang
exaly
Recycling of the urokinase receptor upon internalization of the uPA:serpin complexes
EMBO Journal, 1997Massimo Conese +2 more
exaly