Results 131 to 140 of about 10,821 (196)

Genetic Association and Risk Scores in a COPD Meta-Analysis of 16,707 Subjects [PDF]

, 2017
The heritability of chronic obstructive pulmonary disease (COPD) cannot be fully explained by recognized genetic risk factors identified as achieving genome-wide significance.
Agusti, A, Bakke, P, Beaty, TH, Busch, R, Calverley, PM, Castaldi, PJ, Cho, MH, Crapo, JD, Donner, CF, Gulsvik, A, Hardin, ME, Hawrylkiewicz, I, Hobbs, BD, Hokanson, J, Kim, DK, Kim, WJ, Levy, RD, Litonjua, AA, Lomas, DA, Make, BJ, McGeachie, MJ, NETT Genetics, ECLIPSE, ICGN, and COPDGene Investigators, ., Paré, PD, Rennard, SI, Silverman, EK, Sliwinski, P, Sparrow, D, Tal-Singer, R, Vestbo, J, Wouters, EF, Yim, JJ, Zhou, J   +31 more
core  

Interactions between single nucleotide polymorphism of SERPINA1 gene and smoking in association with COPD: a case–control study

International Journal of COPD, 2017
Xiaowei Deng,1 Cun-hua Yuan,1 De Chang2 1Health Medical Center, 2Department of Respiratory Medicine, General Hospital of Chinese People’s Armed Police Forces, Beijing, People’s Republic of China Background: SERPINA1 gene has been implicated
Deng XW, Yuan CH, Chang D
doaj  

Serpin peptidase inhibitor, clade A (SERPINA1) [PDF]

Science-Business eXchange, 2009
openaire   +1 more source

Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use. [PDF]

, 2019
Tobacco and alcohol use are leading causes of mortality that influence risk for many complex diseases and disorders1. They are heritable2,3 and etiologically related4,5 behaviors that have been resistant to gene discovery efforts6-11.
23andMe Research Team, Bjornsdottir, Gyda, Boardman, Jason D, Boehnke, Michael, Boomsma, Dorret I, Brazel, David M, Chen, Chu, Chen, Fang, Choquet, Hélène, Cucca, Francesco, Datta, Gargi, Davies, Gareth E, Davila-Velderrain, Jose, Docherty, Anna R, Eaton, Charles B, Ehringer, Marissa A, Esko, Tõnu, Faul, Jessica D, Fiorillo, Edoardo, Foerster, Johanna R, Fritsche, Lars G, Gabrielsen, Maiken Elvestad, Gillespie, Nathan A, Gordon, Scott D, Gudbjartsson, Daniel F, Haessler, Jeffrey, Haller, Toomas, Harris, Kathleen Mullan, Heath, Andrew C, Hewitt, John K, Hickie, Ian B, Hokanson, John E, Hopfer, Christian J, Hottenga, Jouke-Jan, Huang, Hongyan, HUNT All-In Psychiatry, Hunter, David J, Iacono, William G, Jang, Seon-Kyeong, Jansen, Philip R, Jiang, Yu, Johnson, Eric O, Kamatani, Yoichiro, Kardia, Sharon LR, Keller, Matthew C, Kellis, Manolis, Kooperberg, Charles, Kraft, Peter, Krauter, Kenneth S, Laakso, Markku, Li, Yue, Lind, Penelope A, Ling, Yueh, Liu, Mengzhen, Loukola, Anu, Lutz, Sharon M, Madden, Pamela AF, Martin, Nicholas G, Matoba, Nana, McGue, Matt, McGuire, Daniel, McMahon, George, McQueen, Matthew B, Medland, Sarah E, Metspalu, Andres, Mohlke, Karen L, Mulas, Antonella, Mägi, Reedik, Nielsen, Jonas B, Okada, Yukinori, Orrù, Valeria, Palviainen, Teemu, Pandit, Anita, Peters, Ulrike, Polderman, Tinca JC, Posthuma, Danielle, Reginsson, Gunnar W, Reiner, Alexander P, Rice, John P, Rimm, Eric, Rose, Richard J, Runarsdottir, Valgerdur, Skogholt, Anne Heidi, Smith, Jennifer A, Stallings, Michael C, Stančáková, Alena, Stefansson, Hreinn, Taylor, Amy E, Thai, Khanh K, Tian, Chao, Tindle, Hilary A, Turman, Constance, Wedow, Robbee, Willemsen, Gonneke, Young, Hannah, Young, Kendra A, Zajac, Gregory JM, Zhan, Xiaowei, Zhao, Wei, Zhou, Wei   +99 more
core  

Case report of a novel alpha1-antitrypsin null variant in Türkiye: Q0RİZE

BMC Pulmonary Medicine
Background Alpha1-antitrypsin (AAT) is a serine protease inhibitor that serves as a counterbalance to the activity of elastases, e.g., neutrophil elastase in lung tissue.
Dilek Karadoğan, Ünal Şahin, Bettina Dreger, Laura Grandoso, Lourdes Osaba   +4 more
doaj   +1 more source

A rapid NGS strategy for comprehensive molecular diagnosis of Birt-Hogg-Dubé syndrome in patients with primary spontaneous pneumothorax [PDF]

, 2016

core   +1 more source

Resistance Heterogeneity and Small Airway Asthma Phenotype [PDF]

, 2019
Kuo, Chris, Lipworth, Brian
core   +3 more sources

超声血流成像结合血清SERPINA1、IFITM1在鉴别子宫肌瘤与子宫腺肌症中的应用价值

Zhongguo shiyan zhenduanxue
目的探究超声血流成像结合血清丝氨酸蛋白酶抑制剂A1（SERPINA1）、干扰素诱导跨膜蛋白1（IFITM1）在鉴别子宫肌瘤与子宫腺肌症中的应用价值。方法选取2021年12月至2022年12月在齐齐哈尔市中医医院经病理确诊的子宫肌瘤患者120例与子宫腺肌症患者90例以及同期健康体检女性60例。所有研究对象均接受经阴道彩色多普勒超声检查。记录子宫及病灶（子宫肌瘤组、子宫腺肌症组）内部及周边，子宫相应区域的收缩期峰值血流速度（PSV）、阻力指数（RI）及搏动指数（PI ...
刘柏, 周苗苗, 李古月, 张红秋
doaj  

SERPINA1 drives TACE resistance in hepatocellular carcinoma by competitively binding ITGB3 to block ITCH-mediated ubiquitination and degradation. [PDF]

Cell Oncol (Dordr)
Zhang L, Bai X, Du M, Dou W, Xie Z, Liu J, Hou Y.   +6 more
europepmc   +1 more source

Clinical implications of a novel SERPINA1 variant c.236 T > A: Challenges in characterizing new rare alpha-1 antitrypsin mutations. [PDF]

Mol Genet Metab Rep
Olivares-Rivera A, Ersöz H, Höger P, Veith M, Greulich T, Schlamp K, Janciauskiene S, Herth F, Trudzinski FC.   +8 more
europepmc   +1 more source