Results 111 to 120 of about 12,528 (235)

Subtractive gene expression profiling of articular cartilage and mesenchymal stem cells: serpins as cartilage-relevant differentiation markers [PDF]

, 2007
SummaryObjectiveMesenchymal stem cells (MSCs) are a population of cells broadly discussed to support cartilage repair. The differentiation of MSCs into articular chondrocytes is, however, still poorly understood on the molecular level.
Boeuf, S., Steck, E., Pelttari, K., Hennig, T., Buneß, A., Benz, K., Witte, D., Sültmann, H., Poustka, A., Richter, W.   +9 more
core   +1 more source

Genetic Susceptibility to Periodontitis

Journal of Periodontal Research, EarlyView.
Aim: The aim of this narrative review was to identify genes carrying risk alleles associated with an increased risk of periodontitis and to place them in a biological context. Methods: The literature was reviewed based on predefined criteria. Results: The identified genes largely fall into functions linking immune response with tissue repair. The genes
Gesa M. Richter, Arne S. Schaefer
wiley   +1 more source

Inflammatory and Immunological Basis of Periodontal Diseases

Journal of Periodontal Research, EarlyView.
The periodontal lesion emerges as an evolving immunological battlefield, where host–microbiome interactions, dysregulated immune responses, fragile resolution mechanisms, and inflammophilic dysbiosis converge to shift the balance from homeostasis to unrestrained tissue destruction.
Giacomo Baima, Marion Arce, Mario Romandini, Thomas Van Dyke   +3 more
wiley   +1 more source

Saliva from nymph and adult females of Haemaphysalis longicornis: a proteomic study [PDF]

, 2015
BACKGROUND: Haemaphysalis longicornis is a major vector of Theileria spp., Anaplasma phagocytophilum, Babesia spp. and Coxiella burnetti in East Asian countries. All life stages of ixodid ticks have a destructive pool-feeding style in which they create a
Albert Mulenga, Antônio F. M. Pinto, Itabajara Da Silva Vaz, John R. Yates, Jolene K. Diedrich, Lucas Tirloni, Mohammad Saiful Islam, Myung-Jo You, Tae Kwon Kim   +8 more
core   +1 more source

Genetic risk variants implicate impaired maintenance and repair of periodontal tissues as causal for periodontitis—A synthesis of recent findings

Periodontology 2000, EarlyView.
AbstractPeriodontitis is a complex inflammatory disease in which the host genome, in conjunction with extrinsic factors, determines susceptibility and progression. Genetic predisposition is the strongest risk factor in the first decades of life. As people age, chronic exposure to the periodontal microbiome puts a strain on the proper maintenance of ...
Arne S. Schaefer, Luigi Nibali, Noha Zoheir, Niki M. Moutsopoulos, Bruno G. Loos   +4 more
wiley   +1 more source

The pathological Trento variant of alpha-1-antitrypsin (E75V) shows non-classical behaviour during polymerization [PDF]

, 2017
Severe alpha-1-antitrypsin deficiency (AATD) is most frequently associated with the alpha-1-antitrypsin (AAT) Z variant (E342K). ZZ homozygotes exhibit accumulation of AAT as polymers in the endoplasmic reticulum of hepatocytes.
Bodker, Chiou, Crooks, Dafforn, Ekeowa, Elliott, Ferrarotti, Ferrarotti, Ferrarotti, Fra, Fra, Gaczynska, Gooptu, Haq, Haq, Hess, Irving, Irving, Jensen, Jeppsson, Knaupp, Koloczek, Laurell, Lomas, Lomas, Lomas, Lomas, Luisetti, Mahadeva, Mahadeva, Medicina, Miranda, Miranda, Morena-Barrio, Motamedi-Shad, Ordonez, Pini, Ronzoni, Schneider, Seo, Stein, Tan, Tan, Tsutsui, Tsutsui, Wu, Yamasaki, Yamasaki, Yu, Zhang, Zhou   +50 more
core   +2 more sources

INVESTIGATION OF ANTICOAGULATION PROPERTIES OF SULFATED GLYCOSAMINOGLYCAN MIMETICS [PDF]

, 2017
INVESTEGATION OF ANTICOAGULATION PROPERTIES OF SULFATED GLYCOSAMINOGLYCAN MIMETICS By Elsamani Ismail Abdelfadiel, MS A thesis submitted in partial fulfillment of the requirements for the degree of Master of Science at Virginia Commonwealth University ...
Abdelfadiel, Elsamani I
core   +1 more source

Exploring the mialome of ticks: An annotated catalogue of midgut transcripts from the hard tick, Dermacentor variabilis (Acari: Ixodidae) [PDF]

, 2008
Background Ticks are obligate blood feeders. The midgut is the first major region of the body where blood and microbes ingested with the blood meal come in contact with the tick's internal tissues.
Daniel E Sonenshine, Jennifer M Anderson, Jesus G Valenzuela   +2 more
core   +4 more sources

Photobiomodulation restores blood–brain barrier integrity after hypoxia via endothelial von Willebrand factor modulation in a humanised tricellular transwell model

The Journal of Physiology, EarlyView.
Abstract figure legend Photobiomodulation restores blood–brain barrier (BBB) integrity following hypoxic stress. A multicellular human BBB model comprising brain microvascular endothelial cells, astrocytes and pericytes was established in a transwell system and subjected to acute hypoxia.
Mirriam Domocos, Denis E. Bragin, Nagesh C. Shanbhag, Luise Schlotterose, Mootaz M. Salman   +4 more
wiley   +1 more source

Effect of Anthocyanin‐Rich New Zealand Blackcurrant on Tumour Necrosis Factor‐α–Induced Plasminogen Activator Inhibitor‐1 Release in Airway Epithelial Cells: A Preliminary Study

Phytochemicals in Food and Medicine, Volume 1, Issue 2, June 2026.
Pretreatment with New Zealand blackcurrant anthocyanins nonsignificantly reduced TNF‐α–induced PAI‐1 release in bronchial epithelial cells. The small sample size may have influenced the lack of statistical significance. This study provides preliminary evidence of possible effects of NZBC anthocyanins on PAI‐1 secretion but warrants further extensive ...
Madiha Ajaz, Ayesha Zahid, Rati Jani, Lada Vugic, Indu Singh, Natalie Shilton   +5 more
wiley   +1 more source