Results 201 to 210 of about 72,366 (294)

Inhibition of the serotonin transporter and risk of heart valve disease: A systematic review and meta-analysis. [PDF]

open access: yesEur J Pharmacol
Campbell A   +9 more
europepmc   +1 more source

From emergence to replacement: The evolution of 3‐methylmethcathinone (3‐MMC) and its substitutes in the Dutch drug market (2012–2024)

open access: yesAddiction, Volume 121, Issue 11, Page 3065-3074, November 2026.
Abstract Background and aims The market for new psychoactive substances (NPS) is highly dynamic, with hundreds of substances emerging on the European drug market in the last decade. 3‐methylmethcathinone (3‐MMC), a synthetic cathinone and isomer of mephedrone (4‐MMC), gained popularity in the Netherlands due to its psychostimulant effects and initial ...
Nadia Robert Petronella Wilhelmina Hutten   +4 more
wiley   +1 more source

Centanafadine (Simtriyo): a triple monoamine reuptake inhibitor for ADHD. [PDF]

open access: yesTrends Pharmacol Sci
Han J   +4 more
europepmc   +1 more source

Direct evidence implicating the asymmetrical dimethylarginine (ADMA)‐dimethylarginine dimethylaminohydrolase 1 (DDAH1) pathway in cerebrovascular dysfunction and stroke pathogenesis in mice

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 21, Page 6422-6443, November 2026.
Abstract Background and Purpose Asymmetrical dimethylarginine (ADMA) is an endogenous inhibitor of nitric oxide synthase (NOS), whereas dimethylaminohydrolase 1 (DDAH1) is primarily responsible for its metabolism. However, the roles of DDAH1 in cerebrovascular regulation are poorly understood. Furthermore, despite evidence that elevated ADMA levels are
Arun Flynn   +10 more
wiley   +1 more source

System-level synchronization and subtype-specific modules govern brain-wide serotonin axon innervation. [PDF]

open access: yesProc Natl Acad Sci U S A
Adams AMJ   +15 more
europepmc   +1 more source

Honokiol regulates Acute respiratory distress syndrome (ARDS)‐associated pulmonary fibrosis via the miR‐19a‐3p/POSTN axis

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 21, Page 6329-6351, November 2026.
Abstract Background and Purpose Acute respiratory distress syndrome (ARDS) and subsequent pulmonary fibrosis are associated with high mortality and limited treatment options. Periostin (POSTN) is a profibrotic mediator predicted to be regulated by microRNA‐19a‐3p (miR‐19a‐3p), but the relevance of this axis in ARDS‐associated pulmonary fibrosis remains
Weilun Liu   +14 more
wiley   +1 more source

Comparison of Laparoscopic and Open Surgery for Appendiceal Mucocele in Terms of Safety and Feasibility. [PDF]

open access: yesJSLS
Yılmaz M   +6 more
europepmc   +1 more source

Subregion‐specific perineuronal net remodelling in the dorsal hippocampus drives vulnerability and resilience to chronic stress: The role of venlafaxine treatment

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 21, Page 6291-6305, November 2026.
Background and Purpose Neuronal plasticity enables the brain to adapt to internal and external demands by dynamically regulating synaptic connectivity and emotional circuitry. Impaired neuroplasticity represents a core pathophysiological framework of major depressive disorder, one of the leading causes of disability worldwide. Chronic stress is a major
Paola Brivio   +11 more
wiley   +1 more source

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