Results 11 to 20 of about 59,858 (305)
Frontiers in Endocrinology, 2022 Since their initial description by Enrico Sertoli in 1865, Sertoli cells have continued to enchant testis biologists. Testis size and germ cell carrying capacity are intimately tied to Sertoli cell number and function.
Victor A. Ruthig +3 more
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Frontiers in Cell and Developmental Biology, 2021 Human Sertoli cell is required for completing normal spermatogenesis, and significantly, it has important applications in reproduction and regenerative medicine because of its great plasticity.
Bang Liu +6 more
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Role of Testosterone in Maintaining Polarity and Differentiated State of Sertoli Cells [PDF]
Translational Research in Urology, 2023 Differentiation and migration of spermatogonial stem cells (SSCs) from the basal to the adluminal compartment of the seminiferous tubules require a well-specialised scaffold created by a well-developed cytoskeleton in the large cytoplasm of the Sertoli ...
Keykavos Gholami +1 more
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Role of androgen and gonadotrophins in the development and function of the Sertoli cells and Leydig cells: data from mutant and genetically modified mice [PDF]
, 2009 Development and maintenance of the male phenotype and establishment of fertility are all dependent upon the activity of the Sertoli cells and Leydig cells of the testis.
Abel, M.H. +4 more
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The Molecular Mechanism of Sex Hormones on Sertoli Cell Development and Proliferation
Frontiers in Endocrinology, 2021 Sustaining and maintaining the intricate process of spermatogenesis is liable upon hormones and growth factors acting through endocrine and paracrine pathways.
Wasim Shah +7 more
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Androblastoma—Sertoli Cell Tumor
Journal of Urology, 1974 An androblastoma in an undescended testicle of a 43 yr old man is reported. Microscopically, the tumor showed zones of neoplastic cells varying in size and shape and separated by fibrous tissue. In some areas the cells were round with eosinophilic cytoplasm and round nuclei. No mitoses were seen.
Kalis, E.G., Goulandris, N.D.
openaire +3 more sources
Effect of FSH on testicular morphology and spermatogenesis in gonadotrophin-deficient hypogonadal mice lacking androgen receptors [PDF]
, 2010 Follicle stimulating hormone (FSH) and androgen act to stimulate and maintain spermatogenesis. FSH acts directly on the Sertoli cells to stimulate germ cell number and acts indirectly to increase androgen production by the Leydig cells.
Abel, M.H. +4 more
core +2 more sources
Asian Journal of Andrology, 2015 This study was designed to explore the regulatory effects of male germ cell secreting factor NODAL on Sertoli cell fate decisions from obstructive azoospermia (OA) and nonobstructive azoospermia (NOA) patients.
Ru-Hui Tian +12 more
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RNF20 is required for male fertility through regulation of H2B ubiquitination in the Sertoli cells
Cell & Bioscience, 2023 Background Spermatogenesis depends on the supporting of the Sertoli cells and their communications with germ cells. However, the regulation of crosstalk between the Sertoli cells and germ cells remains unclear. Results In this report, we used conditional
Fengling Lai +10 more
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Sertoli Cell Immune Regulation: A Double-Edged Sword
Frontiers in Immunology, 2022 The testis must create and maintain an immune privileged environment to protect maturing germ cells from autoimmune destruction. The establishment of this protective environment is due, at least in part, to Sertoli cells.
Rachel L. Washburn +8 more
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