Results 11 to 20 of about 32,723 (247)
Molecular Therapy: Nucleic Acids, 2019 MicroRNAs (miRNAs) play important roles in mammalian spermatogenesis, which is highly dependent on Sertoli cells. However, the functions and mechanisms of miRNAs in regulating human Sertoli cells remain largely unknown.
Chao Yang +14 more
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The Molecular Mechanism of Sex Hormones on Sertoli Cell Development and Proliferation
Frontiers in Endocrinology, 2021 Sustaining and maintaining the intricate process of spermatogenesis is liable upon hormones and growth factors acting through endocrine and paracrine pathways.
Wasim Shah +7 more
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Molecular Mechanisms and Signaling Pathways Involved in Sertoli Cell Proliferation
Frontiers in Endocrinology, 2019 Sertoli cells are somatic cells present in seminiferous tubules which have essential roles in regulating spermatogenesis. Considering that each Sertoli cell is able to support a limited number of germ cells, the final number of Sertoli cells reached ...
Silvina Beatriz Meroni +5 more
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Role of Testosterone in Maintaining Polarity and Differentiated State of Sertoli Cells [PDF]
Translational Research in Urology, 2023 Differentiation and migration of spermatogonial stem cells (SSCs) from the basal to the adluminal compartment of the seminiferous tubules require a well-specialised scaffold created by a well-developed cytoskeleton in the large cytoplasm of the Sertoli ...
Keykavos Gholami +1 more
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Androblastoma—Sertoli Cell Tumor
Journal of Urology, 1974 An androblastoma in an undescended testicle of a 43 yr old man is reported. Microscopically, the tumor showed zones of neoplastic cells varying in size and shape and separated by fibrous tissue. In some areas the cells were round with eosinophilic cytoplasm and round nuclei. No mitoses were seen.
Kalis, E.G., Goulandris, N.D.
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RNF20 is required for male fertility through regulation of H2B ubiquitination in the Sertoli cells
Cell & Bioscience, 2023 Background Spermatogenesis depends on the supporting of the Sertoli cells and their communications with germ cells. However, the regulation of crosstalk between the Sertoli cells and germ cells remains unclear. Results In this report, we used conditional
Fengling Lai +10 more
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Sertoli Cell Immune Regulation: A Double-Edged Sword
Frontiers in Immunology, 2022 The testis must create and maintain an immune privileged environment to protect maturing germ cells from autoimmune destruction. The establishment of this protective environment is due, at least in part, to Sertoli cells.
Rachel L. Washburn +8 more
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Asian Journal of Andrology, 2015 This study was designed to explore the regulatory effects of male germ cell secreting factor NODAL on Sertoli cell fate decisions from obstructive azoospermia (OA) and nonobstructive azoospermia (NOA) patients.
Ru-Hui Tian +12 more
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Scientific Reports, 2022 AbstractThe Sertoli cell (SC)-specific knockout (KO) of connexin43 (Cx43) was shown to be an effector of multiple histological changes in tubular morphology, resulting in germ cell loss through to a Sertoli-cell-only (SCO) phenotype and vacuolated seminiferous tubules containing SC-clusters.
Sarah Staggenborg +11 more
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Apigenin induces oxidative stress in mouse Sertoli TM4 cells [PDF]
Veterinary World, 2021 Background and Aim: Apigenin (API) is an estrogenic compound found in many plants. Sertoli cells reside in the testis and are a key target of environmental toxicants.
Sathaporn Jittapalapong +2 more
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