Results 41 to 50 of about 25,804 (162)

Molecular Mechanisms and Signaling Pathways Involved in Sertoli Cell Proliferation

open access: yesFrontiers in Endocrinology, 2019
Sertoli cells are somatic cells present in seminiferous tubules which have essential roles in regulating spermatogenesis. Considering that each Sertoli cell is able to support a limited number of germ cells, the final number of Sertoli cells reached ...
Silvina Beatriz Meroni   +5 more
doaj   +1 more source

Testicular development in mice lacking receptors for follicle stimulating hormone and androgen. [PDF]

open access: yesPLoS ONE, 2012
Post-natal testicular development is dependent on gonadotrophin and androgen stimulation. Follicle stimulating hormone (FSH) acts through receptors (FSHR) on the Sertoli cell to stimulate spermatogenesis while androgens promote testis growth through ...
Peter J O'Shaughnessy   +2 more
doaj   +1 more source

Melatonin Promotes the Proliferation of Chicken Sertoli Cells by Activating the ERK/Inhibin Alpha Subunit Signaling Pathway

open access: yesMolecules, 2020
Melatonin influences physiological processes such as promoting proliferation and regulating cell development and function, and its effects on chicken Sertoli cells are unknown. Therefore, we investigated the effects of melatonin on cell proliferation and
Ke Xu   +4 more
doaj   +1 more source

Trophic Effect of Porcine Sertoli Cells on Rat and Human Ventral Mesencephalic Cells and Hnt Neurons in Vitro

open access: yesCell Transplantation, 1998
The poor survival of embryonic dopaminergic (DA) neurons transplanted into patients with Parkinson's disease (PD) has encouraged researchers to search for new methods to affect the short- as well as long-term survival of these neurons after ...
Agneta I. Othberg   +6 more
doaj   +1 more source

RU 486 blocks inhibitory effect of neonatal corticosterone administration on sertoli cell proliferation in mice

open access: yesScientific Reports
Cortisol/corticosterone (CORT) are typical glucocorticoids and exert an anti-stress function. p27, a cyclin-dependent kinase inhibitor, acts as a terminal factor for Sertoli cell proliferation at the prepubescent stage. Our previous study showed neonatal
Hidenobu Miyaso   +10 more
doaj   +1 more source

Absence of inhibin alpha and retinoblastoma protein leads to early sertoli cell dysfunction. [PDF]

open access: yesPLoS ONE, 2010
Sertoli cells, the support cells of mammalian spermatogenesis, are regulated by a number of nuclear factors and express retinoblastoma (RB) tumor suppressor protein.
Roopa L Nalam   +2 more
doaj   +1 more source

Identification of a Specific Sertoli Cell Marker, Sox9, for Use in Transplantation

open access: yesCell Transplantation, 2002
The immunoprivileged environment of the testes was first described in the 1930s, and the Sertoli cell was later identified as the main cell type responsible for this phenomenon. Recent work has examined the possibility of recreating this immunoprivileged
R. A. Hemendinger   +4 more
doaj   +1 more source

Sertoli Cells Induce Systemic Donor-Specific Tolerance in Xenogenic Transplantation Model

open access: yesCell Transplantation, 2006
Cell therapy is a potentially powerful tool in the treatment of many grave disorders including leukemia, immune deficiencies, autoimmune diseases, and diabetes.
R. Shamekh   +5 more
doaj   +1 more source

Sertoli Cell

open access: yes
Citation: 'Sertoli cell' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.11208 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
Antoine D. Rolland, Diane Rebourcet
openaire   +2 more sources

Androgen effects on Sertoli cells [PDF]

open access: yesInternational Journal of Andrology, 1990
SummaryMature male rats, γ‐irradiated in utero, were hypophysectomized. In an effort to maintain the seminiferous epithelium, some animals were treated with exogenous androgen while in other animals the seminiferous epithelium was allowed to regress without hormonal treatment. These Sertoli cell‐enriched (SCE) males were evaluated for 7 weeks following
openaire   +2 more sources

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