A Randomized Controlled Trial of Sertraline in Young Children With Autism Spectrum Disorder [PDF]
Frontiers in Psychiatry, 2019 Objective: Selective serotonin reuptake inhibitors like sertraline have been shown in observational studies and anecdotal reports to improve language development in young children with fragile X syndrome (FXS).
Laura A. Potter +18 more
doaj +4 more sources
Molecular Biomarkers Predictive of Sertraline Treatment Response in Young Children With Autism Spectrum Disorder [PDF]
Frontiers in Genetics, 2020 Sertraline is one among several selective serotonin reuptake inhibitors (SSRIs) that exhibited improvement of language development in Autism Spectrum Disorder (ASD); however, the molecular mechanism has not been elucidated.
Reem Rafik Alolaby +8 more
doaj +3 more sources
Protective effects of vitamin E against sertraline-induced oxidative stress on the reproductive system and expression of Bcl-2, Caspase-3 and Hsp70-2 genes in testicular tissue of mice [PDF]
مجله علمی دانشگاه علوم پزشکی کردستان, 2022 Background and Aim: Sertraline is an antidepressant drug and many controversial reports have been presented on the complications of sertraline on the reproductive system.
Hassan Morovvati +2 more
doaj +2 more sources
Sertraline and inflammatory markers in major depression: a systematic review and meta-analysis [PDF]
Annals of General PsychiatryBackground Increasing evidence suggests a link between major depressive disorder (MDD) and inflammatory pathways. Sertraline, a commonly used selective serotonin reuptake inhibitor (SSRI), may influence inflammatory cytokine levels.
ZiLiang Xie +5 more
doaj +2 more sources
The impact of sertraline treatment on obesity, inflammation, blood pressure, and lipid profiles: a systematic review and meta-analysis of randomized controlled trials. [PDF]
Diabetol Metab SyndrWu Y +5 more
europepmc +2 more sources
Sertraline modulates hippocampal plasticity via sigma 1 receptors, cellular stress and neurosteroids [PDF]
Translational PsychiatryIn addition to modulating serotonin transport, selective serotonin reuptake inhibitors (SSRIs) have multiple other mechanisms that may contribute to clinical effects, and some of these latter actions prompt repurposing of SSRIs for non-psychiatric ...
Yukitoshi Izumi +4 more
doaj +2 more sources
The PREDEP-SERT study protocol: A 6-month follow-up cohort study of predictors of effectiveness, tolerability and safety of sertraline for depression using Therapeutic Drug Monitoring. [PDF]
PLoS ONESertraline is a common first-line pharmacological treatment of Major Depressive Disorder (MDD). There is no established consensus nor clinical guidelines for personalized dose adjustments, which imply risks of toxicity and lack of efficacy.
Patricio Molero +8 more
doaj +2 more sources
Adverse Drug Events on the Use of Sertraline in Clinical Studies: A Review
Jurnal Manajemen dan Pelayanan Farmasi, 2021 Major depressive disorder (MDD) and anxiety are known as a widespread public health problem treated with sertraline, a class of Selective Serotonin Reuptake Inhibitor (SSRI) drugs as first-line therapy.
Syahrul Hidayat, Irma M. Puspitasari
doaj +1 more source
La2O3/Co3O4 nanocomposite modified screen printed electrode for voltammetric determination of sertraline [PDF]
Journal of the Serbian Chemical Society, 2020 La2O3/Co3O4 nanocomposite was synthesized and then used for the modification of screen-printed electrode (SPE) prior to the electrochemical determination of sertraline. A significant increment in peak current response was observed and peak potential also
Mohammadi Sayed Zia +4 more
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