Results 31 to 40 of about 52,947 (295)

Sertraline and Phenytoin Drug Interaction in a Geriatric Patient [PDF]

open access: yes, 2017
This report presents the case of a 78-year-old man residing in a nursing home who presented with a 2-month history of increasing lethargy and confusion. These symptoms coincided with the initiation of sertraline in the patient.
Caprio, Thomas V.   +4 more
core   +2 more sources

Inhibition of autophagy flux by sertraline attenuates TRAIL resistance in lung cancer via death receptor 5 upregulation

open access: yesInternational Journal of Molecular Medicine, 2020
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is a potential target for cancer therapy, owing to its ability to selectively kill cancer cells without causing significant toxicity to normal cells.
K. Zinnah, J. Seol, Sang-Youel Park
semanticscholar   +1 more source

The safety and efficacy of botulinum toxin A on the treatment of depression

open access: yesBrain and Behavior, 2021
Objectives Effective strategy for the treatment of depression is limited. This study was to evaluate the safety and efficacy of botulinum toxin A (BoNT/A) in the treatment of depression. Methods Seventy‐six patients were assigned to the BoNT/A group (n = 
Qilin Zhang   +12 more
doaj   +1 more source

Serotonin reuptake inhibitors and cardiovascular disease [PDF]

open access: yes, 2005
Selective serotonin re-uptake inhibiting drugs (SSRIs) are widely used for endogenous depression. In addition to depleting the nerve terminals of serotonin they also lower blood platelet serotonin levels.
Belcher, P.R.   +2 more
core   +1 more source

A meta-analysis of pharmacotherapy for social anxiety disorder: an examination of efficacy, moderators, and mediators [PDF]

open access: yes, 2017
INTRODUCTION: Social anxiety disorder (SAD) is among the most prevalent mental disorders, associated with impaired functioning and poor quality of life. Pharmacotherapy is the most widely utilized treatment option.
Borenstein M   +8 more
core   +2 more sources

Efficacy of Dapoxetine in the Treatment of Patients With Lifelong Premature Ejaculation as an Alternative to Sertraline Therapy

open access: yesSexual Medicine, 2022
: Introduction: Before dapoxetine was approved for the treatment of lifelong premature ejaculation (LPE) in China, daily dosing with off-label sertraline was common. Aim: To investigate the efficacy of dapoxetine in the treatment of patients with LPE as
Guoxiong Liu, MD   +4 more
doaj   +1 more source

Doubly Randomized Preference Trial of Prolonged Exposure Versus Sertraline for Treatment of PTSD.

open access: yesAmerican Journal of Psychiatry, 2019
OBJECTIVE: The authors examined the effect of patient treatment preference on the differential effectiveness of prolonged exposure and sertraline for the treatment of posttraumatic stress disorder (PTSD). METHOD: In a doubly randomized preference trial,
L. Zoellner   +3 more
semanticscholar   +1 more source

Brain serotonin synthesis capacity in obsessive-compulsive disorder: effects of cognitive behavioral therapy and sertraline. [PDF]

open access: yes, 2018
Cognitive behavioral therapy (CBT) and selective serotonin reuptake inhibitors (SSRIs) are both effective treatments for some patients with obsessive-compulsive disorder (OCD), yet little is known about the neurochemical changes related to these ...
Barsoum, Amir   +11 more
core   +2 more sources

Sertraline induces DNA damage and cellular toxicity in Drosophila that can be ameliorated by antioxidants

open access: yesScientific Reports, 2020
Sertraline hydrochloride is a commonly prescribed antidepressant medication that acts by amplifying serotonin signaling. Numerous studies have suggested that children of women taking sertraline during pregnancy have an increased risk of developmental ...
Arpita N. Jajoo   +4 more
semanticscholar   +1 more source

(Poly)Borylated Species as Modern Reactive Groups toward Unusual Synthetic Applications

open access: yesAngewandte Chemie, EarlyView.
In this review, we spotlight recent breakthroughs in α‐polyboron‐substituted carbon‐centered intermediates (carbanion, carbocation, radical, and carbene) and polyborylated alkenes. By bridging fundamental reactivity with the application potential of these extraordinary species, we hope this review will serve as a roadmap for harnessing these unique ...
Nadim Eghbarieh   +5 more
wiley   +2 more sources

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