Results 51 to 60 of about 12,900 (262)

Engineering Antibodies into Targeted Chimeras: From Recognition Modules to Programmable Degraders

open access: yesAdvanced Science, EarlyView.
Antibody can be engineered into diverse lysosome‐targeting chimeras that convert target recognition into active degradation. By coupling antibody binding with recruited receptors, encoded domains, conjugated ligands, or nanoparticle scaffolds, these antibody‐associated targeted chimeras (AbTACs) platforms direct extracellular and membrane proteins ...
Kaige Chen, Quanyin Hu
wiley   +1 more source

Exploring the Entrepreneurial Role of Lawyers: A service-dominant logic paradigm

open access: yesJournal of Modern Science
Objectives This article examines the roles of lawyers in entrepreneurship through the lens of service-dominant logic. Its aim is to understand how lawyers deal with the challenges of entrepreneurship while adhering to their core ethics and practice ...
Maria Urbaniec   +2 more
doaj   +1 more source

LA CO-CREACIÓN Y LOS NUEVOS RETOS DE GENERACIÓN DE VALOR QUE ENFRENTAN LAS ORGANIZACIONES

open access: yesRevista Criterio Libre, 2018
Through an analytical and reflective vision, the aim of this article is to clarify the emerging concept of co-creation, its advantages, limitations, and the processes that facilitate its application. A review of the academic literature from the
Carlos Sánchez-González   +1 more
doaj   +1 more source

Investigations of the Evolved Molecular Basis for Terpenoid Biosynthesis in Marine Sponges

open access: yesAdvanced Science, EarlyView.
Confirming and extending a previous observation in another Bubarida sponge, genomic and functional analyses of A. cavernosa reveal that sponges retain the mevalonate pathway and employ single α‐domain T1TSs and UbiA‐type TSs for terpenoid biosynthesis. The absence of T1TSs clustering with other biosynthetic genes tentatively suggests, based on limited ...
Fangyan Chen   +6 more
wiley   +1 more source

Uncoupling Type I Interferon Benefits From Inflammatory Toxicity: Transformer‐Prioritized Precision Agonists for Potent and Safer Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
A Transformer‐based AI framework, DLINP, screens millions of compounds to identify Co68, a cobalt‐pincer organometallic complex that biases TLR4‐MD2 signaling toward antitumor interferon activation while suppressing inflammatory toxicity through an early TLR4‐SYK‐STAT1 axis.
Xuefei Guo   +10 more
wiley   +1 more source

Terahertz Channel Modeling, Estimation and Localization in RIS‐Assisted Systems

open access: yesAdvanced Electronic Materials, EarlyView.
Reconfigurable intelligent surfaces have become a recent intensive research focus. Based on practical applications, channel strategies for RIS‐assisted terahertz wireless communication systems are categorized into three different types: channel modeling, channel estimation, and channel localization.
Hongjing Wang   +9 more
wiley   +1 more source

Conceptualizing Technical and Vocational Education and Training as a Service Through Service-Dominant Logic

open access: yesSAGE Open
Technical and vocational education and training (TVET) plays a pivotal role in equipping young individuals with technical skills and competencies, enhancing their employability.
Jinfang Cai, Michitaka Kosaka
doaj   +1 more source

Industry Innovation and Brand-Mode Shift

open access: yesMaketingu Janaru, 2019
Brand strategy is defined to be based on the cognition of customers, and is centered on the "exchange, sense, symbol" principle and designed for integration of management, marketing, and communication.
Kazuhiko Mori
doaj   +1 more source

Bridging Performance and Fate: A Framework for Sustainable, Composite‐Based Flexible Electronic Systems

open access: yesAdvanced Electronic Materials, EarlyView.
Composite‐based flexible electronics integrate biodegradable polymers, conductive networks, and multilayer device architectures to balance electrical performance, mechanical durability, and controlled degradation. Interfacial engineering and encapsulation regulate transport stability and operational lifetime, while programmed disassembly enables ...
Sayam, Sangho Cho
wiley   +1 more source

Paslaugos sampratos aktualizavimas šiuolaikinėje vadyboje / Redefining service notion in contemporary management

open access: yesMokslas: Lietuvos Ateitis, 2018
According to the World Bank’s figures, the service sector accounts for 69% of the global GDP and continues to expand. This growth takes place in the environment what has significantly changed and become more complex in the recent decades due to ...
Ilona Skačkauskienė, Jurga Vestertė
doaj   +1 more source

Home - About - Disclaimer - Privacy