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Plant sesquiterpene lactones [PDF]

Philosophical Transactions of the Royal Society B: Biological Sciences
Sesquiterpene lactones (STLs) are a prominent group of plant secondary metabolites predominantly found in the Asteraceae family and have multiple ecological roles and medicinal applications. This review describes the evolutionary and ecological significance of STLs, highlighting their roles in plant defence mechanisms against herbivory and as ...
Olivia Agatha, Daniela Mutwil-Anderwald, Jhing Yein Tan, Marek Mutwil   +3 more
openaire   +4 more sources

Characterization and functional reconstruction of a highly productive germacrene A synthase from Liriodendron chinense. [PDF]

Plant Biotechnol J
Germacrene A Synthase (LcTPS3) from Liriodendron was characterized. The biosynthesis of germacrene A was achieved in a yeast chassis, and the catalytic mechanism of LcTPS3 was further elucidated. Summary Plants produce a large array of natural products which play important roles in flavours, fragrances and medicines.
Cheng W, Zhi Y, Chen F, Xiao X, Lu H, Li R, Zhu H, Wang Q, Fang X, Xu Z, Deng Z, Liu T, Lu L.   +12 more
europepmc   +2 more sources

Germacrene B – a central intermediate in sesquiterpene biosynthesis

Beilstein Journal of Organic Chemistry, 2023
Germacranes are important intermediates in the biosynthesis of eudesmane and guaiane sesquiterpenes. After their initial formation from farnesyl diphosphate, these neutral intermediates can become reprotonated for a second cyclisation to reach the ...
Houchao Xu, Jeroen S. Dickschat
semanticscholar   +1 more source

Anti-Inflammatory and Immunoregulatory Action of Sesquiterpene Lactones

Molecules, 2022
Sesquiterpene lactones (SL), characterized by their high prevalence in the Asteraceae family, are one of the major groups of secondary metabolites found in plants.
A. Paço, T. Brás, Jacqueline O Santos, P. Sampaio, Andreia C Gomes, M. Duarte   +5 more
semanticscholar   +1 more source

Sesquiterpene Lactones: Promising Natural Compounds to Fight Inflammation

Pharmaceutics, 2021
Inflammation is a crucial and complex process that reestablishes the physiological state after a noxious stimulus. In pathological conditions the inflammatory state may persist, leading to chronic inflammation and causing tissue damage.
M. Matos, José D Anastácio, C. Santos
semanticscholar   +1 more source

Anti-inflammatory sesquiterpene and triterpene acids from Mesona procumbens Hemsley

Frontiers in Chemistry, 2022
Mesonaprocumbens Hemsley is a plant conventionally processed to provide popular food materials and herbal medicines in Asia. In this study, six triterpene acids, including five new ones (mesonaic acids D-H, 1–5), and one proximadiol-type sesquiterpene (7)
Hung-Tse Huang, Hung-Tse Huang, I-Wen Lo, Geng-You Liao, Yu-Chi Lin, Yuh-Chiang Shen, Hui-Chi Huang, Tsung-Lin Li, Kung-Ta Lee, Yao-Haur Kuo, Yao-Haur Kuo, Chia-Ching Liaw, Chia-Ching Liaw   +12 more
doaj   +1 more source

Acetylcholinesterase Inhibitory Potential of Various Sesquiterpene Analogues for Alzheimer’s Disease Therapy

Biomolecules, 2021
Alzheimer’s disease (AD) is a gradually growing irreversible illness of the brain that almost affects every fifth person (aged > 80 years) in the world. World Health Organization (WHO) also revealed that the prevalence of this disease will enhance (upto ...
A. Arya, Rubal Chahal, R. Rao, M. Rahman, Deepak Kaushik, M. Akhtar, A. Saleem, S. Khalifa, H. El-Seedi, Mohamed Kamel, G. Albadrani, Mohamed M. Abdel-Daim, Vineet Mittal   +12 more
semanticscholar   +1 more source

SESQUITERPENE RICH VOLATILE SEED OIL OF TAGETES PATULA L. FROM NORTHWEST IRAN [PDF]

Journal of Central European Agriculture, 2011
Hydrodistilled volatile seed oil composition of commonly growing ornamental Tagetes patula L. was analyzed for its constituents by GC/MS. Forty constituents were identified, comprising 94% of the total oil.
M. B. HASSANPOURAGHDAM, F. SHEKARI, J. EMARAT-PARDAZ, M. SAFI SHALAMZARI   +3 more
doaj   +1 more source

Metabolic engineering strategies for sesquiterpene production in microorganism

Critical Reviews in Biotechnology, 2021
Sesquiterpenes are a large variety of terpene natural products, widely existing in plants, fungi, marine organisms, insects, and microbes. Value-added sesquiterpenes are extensively used in industries such as: food, drugs, fragrances, and fuels.
Chun-Li Liu, Kai Xue, Yankun Yang, Xiuxia Liu, Ye Li, T. Lee, Zhonghu Bai, T. Tan   +7 more
semanticscholar   +1 more source

Two New Cytotoxic Sesquiterpene-Amino Acid Conjugates and a Coumarin-Glucoside from Crossostephium chinense

Molecules, 2023
The Asteraceae family is a promising source of bioactive compounds, such as the famous Asteraceae plants Tanacetum cinerariifolium (pyrethrin) and Artemisia annua (artemisinin). As a result of our series of phytochemical studies of the subtropical plants,
Zhichao Wang, Ben-Yeddy Abel Chitama, Keisuke Suganuma, Yoshi Yamano, Sachiko Sugimoto, Susumu Kawakami, Osamu Kaneko, Hideaki Otsuka, Katsuyoshi Matsunami   +8 more
doaj   +1 more source