Modulation of STAT3 signaling, cell redox defenses and cell cycle checkpoints by β-caryophyllene in cholangiocarcinoma cells: possible mechanisms accounting for doxorubicin chemosensitization and chemoprevention [PDF]
, 2020 Cholangiocarcinoma (CCA) is an aggressive group of biliary tract cancers, characterized by late diagnosis, low effective chemotherapies, multidrug resistance, and poor outcomes.
Di Giacomo, Silvia +8 more
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Anti-inflammatory sesquiterpene and triterpene acids from Mesona procumbens Hemsley
Frontiers in Chemistry, 2022 Mesonaprocumbens Hemsley is a plant conventionally processed to provide popular food materials and herbal medicines in Asia. In this study, six triterpene acids, including five new ones (mesonaic acids D-H, 1–5), and one proximadiol-type sesquiterpene (7)
Hung-Tse Huang +12 more
doaj +1 more source
Heteroatom-Containing Natural Sesquiterpene Lactones and Methods for their Obtaining
Eurasian Chemico-Technological Journal, 2013 This review shows the data about isolated heteroatom-containing sesquiterpene lactones from various genera of Asteraceae family, natural occurence, isolation methods and their biological activity.
S. M. Adekenov, G. A. Atazhanova
doaj +1 more source
Antiparasitic activity of chicory (Cichorium intybus) and its natural bioactive compounds in livestock: a review [PDF]
, 2018 Increasing drug resistance in gastrointestinal (GI) parasites of livestock and concerns about chemical residues in animal products and the environment are driving the development of alternative control strategies that are less reliant on the use of ...
Boas, Ulrik +7 more
core +4 more sources
Contribution of microscopy for understanding the mechanism of action against trypanosomatids [PDF]
, 2018 Transmission electron microscopy (TEM) has proved to be a useful tool to study the ultrastructural alterations and the target organelles of new antitrypanosomatid drugs.
A Martinez-Palomo +90 more
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Carbocations and the Complex Flavor and Bouquet of Wine: Mechanistic Aspects of Terpene Biosynthesis in Wine Grapes. [PDF]
, 2015 Computational chemistry approaches for studying the formation of terpenes/terpenoids in wines are presented, using five particular terpenes/terpenoids (1,8-cineole, α-ylangene, botrydial, rotundone, and the wine lactone), volatile compounds (or their ...
Pemberton, Ryan P +2 more
core +2 more sources
Predictability of evolutionary trajectories in fitness landscapes [PDF]
, 2011 Experimental studies on enzyme evolution show that only a small fraction of all possible mutation trajectories are accessible to evolution. However, these experiments deal with individual enzymes and explore a tiny part of the fitness landscape.
A Dawid +57 more
core +5 more sources
Investigating the antiparasitic potential of the marine sesquiterpene avarone, its reduced form avarol, and the novel semisynthetic thiazinoquinone analogue thiazoavarone [PDF]
, 2020 The chemical analysis of the sponge Dysidea avara afforded the known sesquiterpene quinone avarone, along with its reduced form avarol. To further explore the role of the thiazinoquinone scaffold as an antiplasmodial, antileishmanial and antischistosomal
AIELLO, ANNA +13 more
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Terzyme: a tool for identification and analysis of the plant terpenome. [PDF]
, 2018 BACKGROUND: Terpenoid hydrocarbons represent the largest and most ancient group of phytochemicals, such that the entire chemical library of a plant is often referred to as its 'terpenome'.
core +3 more sources
Xanthium strumarium - a potential cheap resource of plant substances for medicinal use [PDF]
, 2019 Xanthium strumarium L. (Asteraceae) is an annual herb which reproduces solely by seed. So far its centre of origin was considered Central or South America. Recent archeological research revealed that the burs of X.
Ionkova I., Kozuharova E., Spadaro V.
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