Plasma p-cresol lowering effect of sevelamer in peritoneal dialysis patients: evidence from a Cross-Sectional Observational Study. [PDF]
PLoS ONE, 2013 p-Cresol is a by-product of the metabolism of aromatic aminoacid operated by resident intestinal bacteria. In patients with chronic kidney disease, the accumulation of p-cresol and of its metabolite p-cresyl-sulphate causes endothelial dysfunction and ...
Bruna Guida +10 more
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Evaluation of the safety and efficacy of transarterial sevelamer embolization in a rabbit liver cancer model: A challenge on the size rule for vascular occlusion [PDF]
Frontiers in Bioengineering and Biotechnology, 2022 As the most efficient method to treat hepatocellular carcinoma in the immediate or advanced stage, transarterial chemoembolization (TACE) is coming into the era of microsphere (MP).
Hong Chen +11 more
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Benefits of Sevelamer on Markers of Bone Turnover in Taiwanese Hemodialysis Patients
Journal of the Formosan Medical Association, 2010 Sevelamer hydrochloride is a recently developed phosphate binder, which is a quaternary amine anion exchanger without calcium or aluminum. Sevelamer is effective in controlling hyperphosphatemia without increasing the calcium load in chronic hemodialysis
Yu-Feng Lin +13 more
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An unusual combination of neurological manifestations and sudden vision loss in a child with familial hyperphosphatemic tumoral calcinosis [PDF]
Annals of Indian Academy of Neurology, 2019 Hyperphosphatemia in the absence of renal failure is an unusual occurrence, particularly in children, but is a common primary feature of familial hyperphosphatemic tumor calcinosis.
Lokesh Lingappa +7 more
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Lower gastrointestinal bleeding in a patient receiving sevelamer: Case report [PDF]
SAGE Open Medical Case Reports, 2021 Phosphate binders such as sevelamer are widely used in patients with chronic kidney disease to lower serum phosphate levels. We present a case of a 67-year-old woman with lower gastrointestinal bleeding after 9 days of using sevelamer carbonate (Renvela ®
Tessa S Schoot +2 more
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Therapeutics and Clinical Risk Management, 2008 Vincenzo Savica1,2, Domenico Santoro1, Paolo Monardo2, Agostino Mallamace1, Guido Bellinghieri11Experimental and Clinic Department of Internal Medicine and Pharmacology, University of Messina, Italy; 2Nephrology and Dialysis Unit, Papardo Hospital ...
Vincenzo Savica +4 more
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Sevelamer-associated ischemic colitis with perforation
Gastroenterology Insights, 2015 We present a case of an 83-year-old woman with end-stage renal disease and hyperphosphatemia treated with sevelamer carbonate, who underwent subtotal colectomy for diffuse bowel necrosis and two perforations in the transverse colon.
Rachel Hudacko, Peter Kaye
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Use of sevelamer in chronic kidney disease: beyond phosphorus control
Nefrología (English Edition), 2015 Sevelamer is a non-calcium phosphate binder used in advanced chronic kidney disease (CKD) and in dialysis for hyperphosphataemia control. Several experimental, observational studies and clinical trials have shown that sevelamer has pleiotropic effects ...
Laura Rodríguez-Osorio +6 more
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Sulfonic acid-functionalized polyallylamine (sevelamer) as an efficient reusable strong solid acid catalyst for the synthesis of xanthenes derivatives [PDF]
BMC Chemistry, 2019 Sevelamer (polyallyamine resin)-supported sulfonic acid (S-SO3H) has been prepared from the reaction of sevelamer with chlorosulfonic acid and characterized using FT-IR spectroscopy, scanning electronmicroscopy (SEM) and thermogravimetric analysis (TGA).
Xian-Liang Zhao +2 more
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A Pan-Inhibitor of Phosphate Transporters AP306 in Hemodialysis Patients [PDF]
Kidney International ReportsIntroduction: Hyperphosphatemia in patients undergoing dialysis is not well-controlled. AP306 is a pan-inhibitor of phosphate transporters, designed to block the active uptake of phosphate through the gastrointestinal tract.
Li Wang +14 more
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