Results 61 to 70 of about 6,360 (195)

Chronic kidney disease in the primary care setting: A narrative review

Journal of General and Family Medicine, Volume 26, Issue 5, Page 385-393, September 2025.
Abstract Chronic kidney disease (CKD) is a growing public health concern globally, with primary care physicians (PCPs) playing a pivotal role in its early detection and management. This review explores the epidemiology, risk factors, screening strategies, and clinical manifestations of CKD within primary care settings.
Faryal Safdar, Ahsan Aslam
wiley   +1 more source

Microbiota signatures in type-2 diabetic patients with chronic kidney disease - A Pilot Study [PDF]

, 2019
The human microbiota is paramount for normal host physiology. Altered host-microbiome interactions are part of the pathogenesis of numerous common ailments.
Chifiriuc, Mariana Carmen, Gradisteanu, Gratiela P., Petcu, Laura, Picu, Ariana, Salmen, Teodor, Serafinceanu, Cristian, Stefan, Diana S., Stoian, Anca P., Stoica, Roxana A., Suceveanu, Adrian P.   +9 more
core   +1 more source

Effects of etelcalcetide on fibroblast growth factor 23 in patients with secondary hyperparathyroidism receiving hemodialysis [PDF]

, 2019
Background: Etelcalcetide is an intravenous calcimimetic approved for treatment of secondary hyperparathyroidism (sHPT) in patients receiving hemodialysis. Besides lowering parathyroid hormone (PTH), etelcalcetide also significantly reduces fibroblast
Block, Geoffrey A., Chertow, Glenn M., Cooper, Kerry, Fouqueray, Bruno, Moe, Sharon M., Oberbauer, Rainer, Sun, Yan, Tomlin, Holly, Vervloet, Marc, Wolf, Myles   +9 more
core   +1 more source

Chronic kidney disease and valvular heart disease: State of the art

Physiological Reports, Volume 13, Issue 18, September 2025.
Abstract Chronic kidney disease (CKD) and valvular heart disease (VHD) frequently coexist and are associated with a significant increase in morbidity and mortality. Their interplay is complex and multifactorial, involving shared pathophysiological mechanisms such as chronic inflammation, mineral and bone disorder, vascular and valvular calcification ...
S. Saltarocchi, M. D'Abramo, P. De Orchi, F. Spunticchia, M. Totaro, E. M. Cirio, F. Miraldi   +6 more
wiley   +1 more source

A randomized, double-blind, placebo-controlled, dose-ranging study using Genz-644470 and sevelamer carbonate in hyperphosphatemic chronic kidney disease patients on hemodialysis

International Journal of Nephrology and Renovascular Disease, 2014
Moustafa Moustafa,1 Lawrence Lehrner,2 Fahd Al-Saghir,3 Mark Smith,4 Sunita Goyal,5 Maureen Dillon,5 John Hunter,5 Randy Holmes-Farley5 1South Carolina Nephrology and Hypertension Center Inc., Orangeburg, SC, USA; 2Kidney Specialists of Southern Nevada ...
Moustafa M, Lehrner L, Al-Saghir F, Smith M, Goyal S, Dillon M, Hunter J, Holmes-Farley R   +7 more
doaj  

"Fish-scales" and graft nephrectomy: unexpected findings at an unusual site [PDF]

Journal of Nephropathology, 2017
Background: Kayexalate and sevelamer are resin medications commonly used in the setting of chronic renal failure for the treatment of hyperkalemia and hyperphosphatemia respectively, are known to cause bowel ischemia, ulcerations, necrosis, pseudotumors ...
Smiley Annie George, Issam Francis
doaj   +1 more source

Phosphate in Physiological and Pathological Mineralization: Important yet Often Unheeded

MedComm, Volume 6, Issue 7, July 2025.
Phosphate serves as a building block for physiological mineralization, and as a signaling molecule that regulates the activity of mineralizing cells. The disturbance in these processes could induce a series of pathological mineralization, with abnormal mineralization of hard tissues and ectopic mineralization of soft tissues being the most ...
Wen Qin, San‐yang Yu, Jia‐lu Gao, Jian‐fei Yan, Qian‐qian Wan, Shuai‐lin Jia, Franklin Tay, Kai Jiao, Lina Niu   +8 more
wiley   +1 more source

New therapies: calcimimetics, phosphate binders and vitamin D receptor activators [PDF]

, 2010
At present, new compounds are available to treat secondary hyperparathyroidism, namely calcimimetics, novel phosphorus binders and also novel vitamin D receptor activactors.
Cannata, J.B. (Jorge), López, Francisco, Rodríguez, Diego, Rodríguez, Minerva, Román-García, Pablo, Tuñón, Diego   +5 more
core  

Is serum phosphorus control related to parathyroid hormone control in dialysis patients with secondary hyperparathyroidism? [PDF]

, 2012
Background Elevated serum phosphorus (P) levels have been linked to increased morbidity and mortality in dialysis patients with secondary hyperparathyroidism (SHPT) but may be difficult to control if parathyroid hormone (PTH) is persistently elevated.
Braun, J., Dehmel, B., Frazao, J.M., Mattin, C., Messa, P., Wilkie, M.   +5 more
core   +4 more sources

Polymeric Anti‐Antibiotic Microparticles to Prevent Antibiotic Resistance Evolution

Small, Volume 21, Issue 21, May 26, 2025.
This study introduces sevelamer (SEV) microparticles as a repurposed adjuvant therapy to combat antimicrobial resistance. SEV microparticles effectively capture vancomycin (VAN) and daptomycin (DAP), preventing these last‐resort antibiotics from driving resistance.
Roya Koshani, Shang‐Lin Yeh, Zeming He, Naveen Narasimhalu, Landon G. vom Steeg, Derek G. Sim, Robert J. Woods, Andrew F. Read, Amir Sheikhi   +8 more
wiley   +1 more source