Results 71 to 80 of about 6,360 (195)

Practical use of sevelamer in chronic kidney disease patients on dialysis in People’s Republic of China

open access: yesTherapeutics and Clinical Risk Management, 2015
Lin Meng,1,2 Bin Fu1 1Department of Nephrology, Second Affiliated Hospital to Tianjin University of Traditional Chinese Medicine, Tianjin, People’s Republic of China; 2Tianjin University of Traditional Chinese Medicine, Tianjin, People’s ...
Meng L, Fu B
doaj  

Do higher dialysate calcium concentrations increase vascular stiffness in haemodialysis patients as measured by aortic pulse wave velocity? [PDF]

open access: yes, 2013
Background: Haemodialysis patients have an increased prevalence of hypertension and risk of cardiovascular mortality and stroke. Higher dialysate calcium concentrations have been reported to cause both an acute and chronic increase in arterial ...
Charitaki, E, Davenport, A
core   +1 more source

Safety and Phosphate‐Binding Capacity of Oxylanthanum Carbonate in Healthy Volunteers

open access: yesClinical and Translational Science, Volume 18, Issue 1, January 2025.
ABSTRACT Despite the widespread use of currently available serum phosphate management options, elevated serum phosphate is common in patients with end‐stage kidney disease on dialysis. Characteristics of currently available phosphate binders that lead to poor patient experiences such as large drug volume size of required daily medication (e.g., many ...
Pablo E. Pergola   +7 more
wiley   +1 more source

Binding interactions with sevelamer and polystyrene sulfonate in vitro

open access: yesPharmacology Research & Perspectives, 2021
This study explored the binding of 28 drugs, which were selected based on frequency of concomitant use and chemical properties, to sevelamer and polystyrene sulfonate in vitro.
Inge R.F. vanBerlo‐van de Laar   +4 more
doaj   +1 more source

Lack of evidence does not justify neglect. how can we address unmet medical needs in calciphylaxis [PDF]

open access: yes, 2016
Calcific uraemic arteriolopathy (CUA), or calciphylaxis, is a rare disease predominantly occurring in comorbidity with dialysis. Due to the very low frequency of CUA, prospective studies on its management are lacking and even anecdotal reports on ...
Brandenburg, Vincent Matthias   +14 more
core   +1 more source

Vascular Calcification in Patients with Chronic Kidney Disease: Types, Clinical Impact and Pathogenesis [PDF]

open access: yes, 2013
Vascular calcification plays a major role in cardiovascular disease, which is one of the main causes of mortality in chronic kidney disease patients. Vascular calcification is determined by prevalent traditional and uraemia-related (non-traditional) risk
Cabezas-Rodríguez, Iván   +5 more
core  

Uremic Pericarditis in a Patient With Hyperphosphatemic Familial Tumoral Calcinosis: Case Report

open access: yesCase Reports in Medicine, Volume 2025, Issue 1, 2025.
Hyperphosphatemic familial tumoral calcinosis (HFTC) is a rare hereditary disorder characterized by defective phosphate homeostasis, leading to ectopic calcium deposition in soft tissues. This case report describes a 41 year‐old Jordanian male with HFTC and stage 5 chronic kidney disease (CKD) secondary to nonsteroidal anti‐inflammatory drug (NSAID ...
Rana A. Nabalawi, Poulami Jha
wiley   +1 more source

Effect of Sevelamer on Mineral and Lipid Abnormalities in Hemodialysis Patients

open access: yesSaudi Journal of Kidney Diseases and Transplantation, 2008
We conducted a prospective study in hemodialysis patients to assess the safety and efficacy of sevelamer, a non-absorbable phosphate binding polymer free of calcium and aluminum, in lowering serum phosphorus, serum intact parathyroid hormone, and serum ...
Hamida Fethi   +8 more
doaj  

The role of the gastrointestinal tract in phosphate homeostasis in health and chronic kidney disease. [PDF]

open access: yes, 2013
For a number of years, there has been increasing interest in the concept of directly targeting intestinal phosphate transport to control hyperphosphatemia in chronic kidney disease. However, progress has been slow due to the paucity of information on the
Debnam, ES, Marks, J, Unwin, RJ
core   +1 more source

Dose–response efficacy and safety of PA21 in Japanese hemodialysis patients with hyperphosphatemia: a randomized, placebo-controlled, double-blind, Phase II study [PDF]

open access: yes, 2015
Seiring dengan menguatnya ideologi nasionalis-sekuler pascakemerdekaan, muncullah konsep nasionalisme berdasarkan sejumlah sumber yang bertolak belakang satu sama lain.
Fumihiko Koiwa, Akira Terao
core   +2 more sources

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