Results 51 to 60 of about 2,895 (208)
Therapeutic Apheresis and Dialysis, Volume 30, Issue 3, Page 309-322, June 2026.ABSTRACT Secondary hyperparathyroidism (SHPT) is a common complication in patients receiving maintenance dialysis, driven by calcium and phosphate metabolism disturbances. Calcimimetics are central to the management of SHPT by enhancing calcium‐sensing receptor sensitivity and reducing parathyroid hormone secretion.
Fumihiko Koiwa +3 more
wiley +1 more source
Mechanism of Action and Clinical Attributes of Auryxia® (Ferric Citrate). [PDF]
, 2019 Chronic kidney disease (CKD) is a major cause of morbidity and premature mortality and represents a significant global public health issue. Underlying this burden are the many complications of CKD, including mineral and bone disorders, anemia, and ...
Bino, Avi +2 more
core
Do higher dialysate calcium concentrations increase vascular stiffness in haemodialysis patients as measured by aortic pulse wave velocity? [PDF]
, 2013 Background: Haemodialysis patients have an increased prevalence of hypertension and risk of cardiovascular mortality and stroke. Higher dialysate calcium concentrations have been reported to cause both an acute and chronic increase in arterial ...
Charitaki, E, Davenport, A
core +1 more source
PLoS ONE, 2017 BackgroundChronic kidney disease-mineral and bone disorder (CKD-MBD), a complication of chronic kidney disease, has been linked to reduced quality and length of life. High serum phosphate levels that result from CKD-MBD require phosphate-lowering agents,
Nigar Sekercioglu +7 more
doaj +1 more source
Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes
Advanced Functional Materials, Volume 36, Issue 1, 2 January 2026.Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth +2 more
wiley +1 more source
Dose–response efficacy and safety of PA21 in Japanese hemodialysis patients with hyperphosphatemia: a randomized, placebo-controlled, double-blind, Phase II study [PDF]
, 2015 Seiring dengan menguatnya ideologi nasionalis-sekuler pascakemerdekaan, muncullah konsep nasionalisme berdasarkan sejumlah sumber yang bertolak belakang satu sama lain.
Fumihiko Koiwa, Akira Terao
core +2 more sources
Sevelamer-Induced Gastrointestinal Injury Presenting as Gastroenteritis
Case Reports in Gastroenterology, 2018 End-stage renal disease (ESRD) is a common disease encountered in clinical practice and is associated with increasing metabolic derangements through disease progression.
Jared Magee +2 more
doaj +1 more source
Clinical Pharmacology &Therapeutics, Volume 119, Issue 1, Page 228-240, January 2026.Data science approaches have been increasingly implemented in healthcare big data to evaluate the safety and effectiveness of drugs. Association discovery is a data mining approach that finds potentially associated elements in high‐dimensional data. We present a novel implementation of the association discovery approach in longitudinal healthcare data ...
George S. Q. Tan +6 more
wiley +1 more source
The Egyptian Journal of Internal Medicine, 2015 Background The non-calcium-based phosphate binder sevelamer hydrochloride was developed to provide chronic kidney disease patients with a polymer capable of managing hyperphosphatemia without an increase in the calcium load.
Bahaa Eldin Zayed +5 more
doaj +1 more source
A Perfect Storm in Mineral Handling
Case Reports in Nephrology, Volume 2026, Issue 1, 2026.Introduction One of the commonest complications of end‐stage renal disease (ESRD) is the disruption of normal mineral trafficking, with a major perturbation in the handling of calcium and phosphate. Background Here, we report a patient who presented some time ago along with his imaging, with some of the worst sequelae of these issues.
Wael L. Jebur +2 more
wiley +1 more source