Results 61 to 70 of about 2,895 (208)

A comparison between the combined effect of calcium carbonate with sucroferric oxyhydroxide and other phosphate binders: an in vitro and in vivo experimental study

open access: yesBMC Nephrology, 2019
Background Approximately 30% of patients on dialysis received combination therapy for their phosphate binder prescription; however, few studies for combined effects of phosphate binders are reported.
Atsushi Yaguchi   +7 more
doaj   +1 more source

The role of the gastrointestinal tract in phosphate homeostasis in health and chronic kidney disease. [PDF]

open access: yes, 2013
For a number of years, there has been increasing interest in the concept of directly targeting intestinal phosphate transport to control hyperphosphatemia in chronic kidney disease. However, progress has been slow due to the paucity of information on the
Debnam, ES, Marks, J, Unwin, RJ
core   +1 more source

Single Center, Open‐Label, Randomized Crossover Trial on Drug–Drug Interactions of Levothyroxine/Magnesium‐Citrate and Levothyroxine/Magnesium‐Aspartate in Healthy Subjects—The ThyroMag Trial

open access: yesClinical and Translational Science, Volume 18, Issue 11, November 2025.
ABSTRACT Divalent cations such as calcium and ferrous sulfate interfere with the absorption of levothyroxine due to complexing. To our knowledge, the effects of magnesium on levothyroxine absorption have never been studied. The open‐label cross‐over pharmacokinetic study was conducted in 15 healthy, euthyroid adults.
Martin Christian Attinger   +5 more
wiley   +1 more source

The intestine and the kidneys : a bad marriage can be hazardous [PDF]

open access: yes, 2015
The concept that the intestine and chronic kidney disease influence each other, emerged only recently. The problem is multifaceted and bidirectional. On one hand, the composition of the intestinal microbiota impacts uraemic retention solute production ...
Glorieux, Griet, Vanholder, Raymond
core   +1 more source

Sevelamer carbonate in the treatment of hyperphosphatemia in patients with chronic kidney disease on hemodialysis

open access: yesTherapeutics and Clinical Risk Management, 2008
Vincenzo Savica1,2, Domenico Santoro1, Paolo Monardo2, Agostino Mallamace1, Guido Bellinghieri11Experimental and Clinic Department of Internal Medicine and Pharmacology, University of Messina, Italy; 2Nephrology and Dialysis Unit, Papardo Hospital ...
Vincenzo Savica   +4 more
doaj  

Development of Deferoxamine‐Functionalized Cyclodextrin Polymer for Targeted Iron Chelation

open access: yesChemistryOpen, Volume 14, Issue 10, October 2025.
The cyclodextrin polymer is conjugated with 35 deferoxamine units and can form iron(III) complexes. The polymer exhibits significantly lower antiproliferative activity than free deferoxamine. The cyclodextrin polymer with multiple deferoxamine units may present a promising strategy for improving the efficacy of iron chelation therapies.
Roberta Panebianco   +2 more
wiley   +1 more source

Chronic kidney disease in the primary care setting: A narrative review

open access: yesJournal of General and Family Medicine, Volume 26, Issue 5, Page 385-393, September 2025.
Abstract Chronic kidney disease (CKD) is a growing public health concern globally, with primary care physicians (PCPs) playing a pivotal role in its early detection and management. This review explores the epidemiology, risk factors, screening strategies, and clinical manifestations of CKD within primary care settings.
Faryal Safdar, Ahsan Aslam
wiley   +1 more source

Vascular Calcification in Patients with Chronic Kidney Disease: Types, Clinical Impact and Pathogenesis [PDF]

open access: yes, 2013
Vascular calcification plays a major role in cardiovascular disease, which is one of the main causes of mortality in chronic kidney disease patients. Vascular calcification is determined by prevalent traditional and uraemia-related (non-traditional) risk
Cabezas-Rodríguez, Iván   +5 more
core  

Deleting death and dialysis: Conservative care of cardio-vascular risk and kidney function loss in chronic kidney disease (CKD) [PDF]

open access: yes, 2018
The uremic syndrome, which is the clinical expression of chronic kidney disease (CKD), is a complex amalgam of accelerated aging and organ dysfunctions, whereby cardio-vascular disease plays a capital role. In this narrative review, we offer a summary of
Castillo-Rodriguez, Esmeralda   +5 more
core   +4 more sources

The Effects of Sevelamer Hydrochloride and Calcium Carbonate on Kidney Calcification in Uremic Rats [PDF]

open access: yesJournal of the American Society of Nephrology, 2002
The control of serum phosphorus (P) and calcium-phosphate (Ca x P) product is critical to the prevention of ectopic calcification in chronic renal failure (CRF). Whereas calcium (Ca) salts, the most commonly used phosphate binders, markedly increase serum Ca and positive Ca balance, the new calcium- and aluminum-free phosphate binder, sevelamer ...
M. Cozzolino   +6 more
openaire   +3 more sources

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