Results 61 to 70 of about 1,973 (178)
Renal Failure, 2021 Objective The aim of this study was to determine the efficacy and safety of lanthanum carbonate (LC) versus calcium salts, non-LC phosphate binders (PBs), sevelamer, or placebo in patients with chronic kidney disease (CKD).
Lijuan Zhao, An Liu, Guoshuang Xu
doaj +1 more source
Chronic kidney disease in the primary care setting: A narrative review
Journal of General and Family Medicine, Volume 26, Issue 5, Page 385-393, September 2025.Abstract Chronic kidney disease (CKD) is a growing public health concern globally, with primary care physicians (PCPs) playing a pivotal role in its early detection and management. This review explores the epidemiology, risk factors, screening strategies, and clinical manifestations of CKD within primary care settings.
Faryal Safdar, Ahsan Aslam
wiley +1 more source
Trials, 2011 Background Serum phosphate is an independent predictor of cardiovascular morbidity and mortality in patients with chronic kidney disease and the general population.
Steeds Richard P +3 more
doaj +1 more source
PILOTSTUDY TO EVALUATE THE EFFECT OF PHOSPHORUSBINDERS ON FGF23
Kidney Research and Clinical Practice, 2012 The Netherlands Fibroblast growth Factor 23 (FGF23) is independently associated with cardiovasculair outcome. A reduction of dietary phosphorus intake in healthy individuals leads to a decrease of FGF23.
A.Bouma de Krijger +3 more
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International Journal of Nephrology, 2018 Background. Hyperphosphatemia in chronic kidney disease (CKD) patients is often treated with calcium carbonate (CaCO3) despite the fact that CaCO3 is associated with increased calcium load and potentially increased cardiovascular risk.
B. L. Goh, A. Soraya, A. Goh, K. L. Ang
doaj +1 more source
Phosphate binders affect vitamin K concentration by undesired binding, an in vitro study
BMC Nephrology, 2017 Background Vascular calcification is a major contributing factor to mortality in end stage renal disease (ESRD). Despite the efficacy of phosphate binders to improve hyperphosphatemia, data on vascular calcification are less clear.
A. Neradova +5 more
doaj +1 more source
Phosphate in Physiological and Pathological Mineralization: Important yet Often Unheeded
MedComm, Volume 6, Issue 7, July 2025.Phosphate serves as a building block for physiological mineralization, and as a signaling molecule that regulates the activity of mineralizing cells. The disturbance in these processes could induce a series of pathological mineralization, with abnormal mineralization of hard tissues and ectopic mineralization of soft tissues being the most ...
Wen Qin +8 more
wiley +1 more source
Polymeric Anti‐Antibiotic Microparticles to Prevent Antibiotic Resistance Evolution
Small, Volume 21, Issue 21, May 26, 2025.This study introduces sevelamer (SEV) microparticles as a repurposed adjuvant therapy to combat antimicrobial resistance. SEV microparticles effectively capture vancomycin (VAN) and daptomycin (DAP), preventing these last‐resort antibiotics from driving resistance.
Roya Koshani +8 more
wiley +1 more source
, 2016 Purpose: Powdered sevelamer carbonate is a new phosphate binder with unproven therapeutic benefit in Indian population. Hence, we aimed to compare its efficacy and safety with calcium acetate in patients with Chronic Renal Disease on hemodialysis ...
Narula, Jasleen +3 more
core +1 more source
Safety and Phosphate‐Binding Capacity of Oxylanthanum Carbonate in Healthy Volunteers
Clinical and Translational Science, Volume 18, Issue 1, January 2025.ABSTRACT Despite the widespread use of currently available serum phosphate management options, elevated serum phosphate is common in patients with end‐stage kidney disease on dialysis. Characteristics of currently available phosphate binders that lead to poor patient experiences such as large drug volume size of required daily medication (e.g., many ...
Pablo E. Pergola +7 more
wiley +1 more source