Results 71 to 80 of about 2,895 (208)

Effect of bixalomer on coronary artery calcification in hemodialysis patients with hyperphosphatemia: a multi-center, randomized controlled trial

Renal Replacement Therapy, 2019
Background Calcium carbonate is a first-line therapy for hyperphosphatemia in hemodialysis patients but is associated with progressive coronary and aortic calcification. Sevelamer compounds are alternatives to calcium-containing phosphate binders as they
Takashi Akiba, Keitaro Yokoyama, Hiroki Hase, Masahide Mizobuchi, Ryoichi Ando, Shuji Sakai, Kenji Fukushima, Tadao Akizawa   +7 more
doaj   +1 more source

Safety and effectiveness of lanthanum carbonate for hyperphosphatemia in chronic kidney disease (CKD) patients: a meta-analysis

Renal Failure, 2021
Objective The aim of this study was to determine the efficacy and safety of lanthanum carbonate (LC) versus calcium salts, non-LC phosphate binders (PBs), sevelamer, or placebo in patients with chronic kidney disease (CKD).
Lijuan Zhao, An Liu, Guoshuang Xu
doaj   +1 more source

Sevelamer, a phosphate-binding resin with beneficial effect in diabetic kidney disease; a modern paradigm shift [PDF]

, 2014
The proportion of individuals diagnosed with diabetes mellitus is increasing throughout the world, which sequentially drives upward the global frequency of diabetic kidney disease (1, 2). Diabetes is a costly and deadly disease.
Baradaran, Azar., Beladi Mousavi, Seyed seifollah., Mardani, Saeed., Shahbazian, Heshmatollah., Tamadon, Mohammad Reza.   +4 more
core  

Evaluating the effects of sevelamer carbonate on cardiovascular structure and function in chronic renal impairment in Birmingham: the CRIB-PHOS randomised controlled trial

Trials, 2011
Background Serum phosphate is an independent predictor of cardiovascular morbidity and mortality in patients with chronic kidney disease and the general population.
Steeds Richard P, Townend Jonathan N, Chue Colin D, Ferro Charles J   +3 more
doaj   +1 more source

Effects of Sevelamer Hydrochloride and Calcium Carbonate on Renal Osteodystrophy in Hemodialysis Patients [PDF]

Journal of the American Society of Nephrology, 2008
Disturbances in mineral metabolism play a central role in the development of renal bone disease. In a 54-wk, randomized, open-label study, 119 hemodialysis patients were enrolled to compare the effects of sevelamer hydrochloride and calcium carbonate on bone.
Ferreira, A, Frazão, JM, Monier-Faugere, MC, Gil, C, Galvão, J, Oliveira, C, Baldaia, J, Rodrigues, I, Santos, C, Ribeiro, S, Hoenger, R, Duggal, A, Malluche, HH   +12 more
openaire   +3 more sources

Phosphate in Physiological and Pathological Mineralization: Important yet Often Unheeded

MedComm, Volume 6, Issue 7, July 2025.
Phosphate serves as a building block for physiological mineralization, and as a signaling molecule that regulates the activity of mineralizing cells. The disturbance in these processes could induce a series of pathological mineralization, with abnormal mineralization of hard tissues and ectopic mineralization of soft tissues being the most ...
Wen Qin, San‐yang Yu, Jia‐lu Gao, Jian‐fei Yan, Qian‐qian Wan, Shuai‐lin Jia, Franklin Tay, Kai Jiao, Lina Niu   +8 more
wiley   +1 more source

New therapies: calcimimetics, phosphate binders and vitamin D receptor activators [PDF]

, 2010
At present, new compounds are available to treat secondary hyperparathyroidism, namely calcimimetics, novel phosphorus binders and also novel vitamin D receptor activactors.
Cannata, J.B. (Jorge), López, Francisco, Rodríguez, Diego, Rodríguez, Minerva, Román-García, Pablo, Tuñón, Diego   +5 more
core  

PILOTSTUDY TO EVALUATE THE EFFECT OF PHOSPHORUSBINDERS ON FGF23

Kidney Research and Clinical Practice, 2012
The Netherlands Fibroblast growth Factor 23 (FGF23) is independently associated with cardiovasculair outcome. A reduction of dietary phosphorus intake in healthy individuals leads to a decrease of FGF23.
A.Bouma de Krijger, P.M. ter Wee, F.J. van Ittersum, M.G. Vervloet   +3 more
doaj   +1 more source

Polymeric Anti‐Antibiotic Microparticles to Prevent Antibiotic Resistance Evolution

Small, Volume 21, Issue 21, May 26, 2025.
This study introduces sevelamer (SEV) microparticles as a repurposed adjuvant therapy to combat antimicrobial resistance. SEV microparticles effectively capture vancomycin (VAN) and daptomycin (DAP), preventing these last‐resort antibiotics from driving resistance.
Roya Koshani, Shang‐Lin Yeh, Zeming He, Naveen Narasimhalu, Landon G. vom Steeg, Derek G. Sim, Robert J. Woods, Andrew F. Read, Amir Sheikhi   +8 more
wiley   +1 more source

Vitamin K antagonists predispose to calciphylaxis in patients with end-stage renal disease. [PDF]

, 2015
BACKGROUND/AIMS: Calciphylaxis is associated with a poor prognosis in dialysis patients, and its pathogenesis remains incompletely understood. Although the use of vitamin K antagonists (VKA) has been implicated, previous reports are conflicting. We aimed
Bardsley, Victoria, El-Damanawi, Ragada, Fry, Andrew C, Galloway, Peter AG, Hiemstra, Thomas F, Ojha, Sanjay K, Pritchard, Nicholas R   +6 more
core   +1 more source