Results 101 to 110 of about 4,122,734 (351)
Allergy, Asthma & Clinical Immunology, 2021 Background Differences between adult patients with severe early-onset and late-onset asthma have not been well studied. Objectives To determine the phenotypic distinction regarding age at onset in patients with severe asthma.
Dandan Chen +7 more
doaj +1 more source
Metalloproteinases and their Inhibitors under the Course of Immunostimulation by CPG-ODN and Specific Antigen Inhalation in Equine Asthma [PDF]
, 2019 Objectives. Inhalation of immunostimulatory bacterial DNA segments (cytosine-phosphate-guanosine-oligodeoxynucleotides, CpG-ODN) normalizes clinical and cytologic parameters in severe equine asthma.
Barton, Ann Kristin +5 more
core +1 more source
Different endotypes and phenotypes drive the heterogeneity in severe asthma
Allergy. European Journal of Allergy and Clinical Immunology, 2020 The identification of sputum eosinophilia indicating corticosteroid responsiveness in subjects with severe asthma heralded the beginning of phenotyping asthmatic subjects based on airways inflammation.
P. McDowell, L. Heaney
semanticscholar +1 more source
Advanced Science, EarlyView.This study aims to evaluate the impact of the potassium channel KCNJ2 on asthma development. KCNJ2 promotes NLRP3 inflammasome activation through both Ca2+ influx and K+ efflux in airway epithelial cells, which drives allergic airway inflammation and remodeling, suggesting a promising therapeutic target for asthma.
Yachao Cui +10 more
wiley +1 more source
Airway remodelling assessed by sputum and high resolution computed tomography in asthma and COPD [PDF]
, 2004 It is not known whether sputum elastase, metalloproteinase (MMP)-9 and tissue-inhibitor metalloproteinase (TIMP)-1 are related to structural changes of the airways, as assessed by high-resolution computed tomography (HRCT) scan. The relationships between
Bellia, M. +9 more
core +1 more source
Advanced Science, EarlyView.Cer24:1 levels are reduced in neutrophilic asthma and inversely correlate with disease severity and airway neutrophilia. Restoring Cer24:1 suppresses pathogenic Th17 differentiation by engaging EP2 on CD4+ T cells, thereby dampening the JAK2–STAT3–RORγt axis and reducing IL‐17 production.
Huan Liu +11 more
wiley +1 more source
Kocatepe Tıp Dergisi, 2018 Asthma is a common inflammatory disease that has wideclinical characteristics of the airway of the lungs. Asthmasymptoms can be prevented by avoiding triggers likeallergens and by the effective inhaled treatment. Themajority of asthma patients can be treated effectivelyby current medications.
SAĞMEN, Seda Beyhan, CEYHAN, Berrin
openaire +4 more sources
Chicago Asthma Epidemic: The Status of Asthma in Chicago [PDF]
, 2007 Chicago is known for many things, our great food and architecture. Unfortunately, we are also known for being an epi-center for asthma. We lead the Nation in asthma deaths, emergency room visits and hospitalizations.
core
Preschool children with asthma: Do their GPs know? [PDF]
, 1999 Objective: To answer the following question: Are children with asthma known to their GP? Methods: Parents of all 464 children, 1-3 years of age and registered with five general practices, received a postal questionnaire asking about asthma symptoms of ...
Jongste, J.C. (Johan) de +5 more
core +1 more source
AGING MEDICINE, EarlyView.Geriatric asthmatics exhibit more comorbidities, poorer lung function, higher neutrophil ratios, and elevated CRP levels. ABSTRACT Objective The research analyzed the clinical characteristics of geriatric and nongeriatric asthma cases, aiming to provide new insights into the diagnosis and management of geriatric asthma for clinicians.
Mengxia Gu +4 more
wiley +1 more source