Results 81 to 90 of about 4,122,734 (351)

Prevalence and management of severe asthma in the Nordic countries: findings from the NORDSTAR cohort

ERJ Open Research, 2023
Background Real-life evidence on prevalence and management of severe asthma is limited. Nationwide population registries across the Nordic countries provide unique opportunities to describe prevalence and management patterns of severe asthma at ...
Susanne Hansen, Anna von Bülow, Patrik Sandin, Olivia Ernstsson, Christer Janson, Lauri Lehtimäki, Hannu Kankaanranta, Charlotte Ulrik, Bernt Bøgvald Aarli, Hanna Fues Wahl, Kirk Geale, Sheila Tuyet Tang, Maija Wolf, Tom Larsen, Alan Altraja, Helena Backman, Maritta Kilpeläinen, Arja Viinanen, Dora Ludviksdottir, Paula Kauppi, Asger Sverrild, Sverre Lehmann, Vibeke Backer, Valentyna Yasinska, Tina Skjold, Jussi Karjalainen, Apostolos Bossios, Celeste Porsbjerg   +27 more
doaj   +1 more source

Latino Asthma Epidemic [PDF]

, 2009
Chicago is known for many things, our great food and architecture. Unfortunately, we are also known for being an epi-center for asthma. We lead the Nation in asthma deaths, emergency room visits and hospitalizations.

core  

Pediatric severe asthma: A case series report and perspectives on anti-IgE treatment [PDF]

, 2018
Background The primary goal of asthma management is to achieve disease control for reducing the risk of future exacerbations and progressive loss of lung function. Asthma not responding to treatment may result in significant morbidity.
Mirra, Virginia, Montella, Silvia, Santamaria, Francesca   +2 more
core   +1 more source

Molecular Targets for Biological Therapies of Severe Asthma

Frontiers in Immunology, 2020
Asthma is a heterogeneous respiratory disease characterized by usually reversible bronchial obstruction, which is clinically expressed by different phenotypes driven by complex pathobiological mechanisms (endotypes).
C. Pelaia, C. Crimi, A. Vatrella, C. Tinello, R. Terracciano, G. Pelaia   +5 more
semanticscholar   +1 more source

Respiratory Organ‐on‐a‐Chip for Disease Modeling: From Architecture to Functional Integration

Advanced Healthcare Materials, EarlyView.
Respiratory organ‐on‐a‐chip (ROC) models capture key mechanical and cellular cues of the human respiratory system, enabling quantitative dissection of disease mechanisms. This review links ROC architectures to disease modeling, functional integration, and commercialization, and proposes a decision framework that aligns model complexity with mechanistic
Jinzhuo Hu, Yongjie Tang, Sidi Liu, Tao Xu, Qian Liu   +4 more
wiley   +1 more source

Tezepelumab in near-fatal asthma requiring VV-ECMO

Respiratory Medicine Case Reports
Phase III studies have demonstrated that the anti-TSLP biologic tezepelumab significantly reduces asthma exacerbations in severe asthma, regardless of endotype. However, evidence on its use in near-fatal asthma is lacking. Tezepelumab's ability to reduce
Elisa Bentivegna, Greta Insalata, Luca Paita, Alessia Catalisano, Chiara Allegrini, Giovanni Cianchi, Manuela Bonizzoli, Federico Lavorini, Gianna Camiciottoli   +8 more
doaj   +1 more source

The Role of Primary Care in Asthma Control and Severity

Spectrum, 2019
Background: Asthma is a common chronic inflammatory disease of the airways affecting 3 million Canadians. Primary Care Providers (PCPs) are integral to care coordination, enhanced through the development of a strong patient-PCP relationship with ...
Joel Agarwal, Monette Dimitrov, Kerri MacKay, Alan Kaplan, Donald Cockcroft, Dilini Vethanayagam   +5 more
doaj   +1 more source

Ambient particulate pollution and the world-wide prevalence of asthma, rhinoconjunctivitis and eczema in children: Phase One of the International Study of Asthma and Allergies in Childhood (ISAAC) [PDF]

, 2010
Objectives: To investigate the effect of ambient particulate matter on variation in childhood prevalence of asthma, rhinoconjunctivitis and eczema.
Anabwani, G., Anderson, H. R., Asher, M. I., Aït-Khaled, N., Beasley, R., Björkstén, B., Brunekreef, B., Burr, M. L., Clayton, T. O., Crane, J., Ellwood, P., Kapetanakis, V., Keil, U., Lai, C. K. W., Mallol, J., Martinez, F. C., Mitchell, E. A., Montefort, S., Mutius, Erika von, Pandey, K.D., Pearce, N., Robertson, C. F., Ruggles, R., Shah, J. R., Stewart, A. W., Strachan, D. P., Weiland, S. K., Williams, H. C.   +27 more
core   +1 more source

Chronic rhinosinusitis with nasal polyps impact in severe asthma patients: Evidences from the Severe Asthma Network Italy (SANI) registry.

Respiratory Medicine, 2020
BACKGROUND The clinical and laboratory features of patients enrolled in the Severe Asthma Network in Italy (SANI) registry, a web-based observatory collecting demographic, clinical, functional and inflammatory data of patients with severe asthma were ...
G. Canonica, L. Malvezzi, F. Blasi, P. Paggiaro, M. Mantero, G. Senna, E. Heffler   +6 more
semanticscholar   +1 more source

High Humidity Exacerbates Psoriasiform Skin Disease Relapse by Increasing Tissue‐Resident Memory T Cells via Altering Skin Microbiota

Advanced Science, EarlyView.
We demonstrated that high humidity worsened psoriasis relapse in murine psoriasiform skin inflammation by increasing skin‐resident memory CD8+ cells via upregulating IL‐15Rα on keratinocytes. The increases in IL‐15Rα and memory CD8+ cells were attributed to S. nepalensis and its metabolite ADMA in skin exposed to high humidity.
Chun‐Ling Liang, Yuchao Chen, Chuanjian Lu, Huazhen Liu, Fenglian Qin, Sisi Dai, Feifei Qiu, Haiming Chen, Weihui Lu, Jonathan S. Bromberg, Zhenhua Dai   +10 more
wiley   +1 more source