Results 141 to 150 of about 287,217 (298)

Close linkage of the locus for X chromosome-linked severe combined immunodeficiency to polymorphic DNA markers in Xq11-q13.

, 1987
Geneviève de Saint Basile, Benoı̂t Arveiler, I. Oberlé, S Malcolm, R J Levinsky, YL Lau, Marten H. Hofker, Marianne Debré, Alain Fischer, C Griscelli   +9 more
openalex   +2 more sources

Purine nucleoside metabolism in the erythrocytes of patients with adenosine deaminase deficiency and severe combined immunodeficiency. [PDF]

, 1976
R. P. Agarwal, Gerald W. Crabtree, Robert E. Parks, J. Arly Nelson, Richard G. Keightley, Robertson Parkman, Fred S. Rosen, Robert C. Stern, Stephen H. Polmar   +8 more
openalex   +1 more source

Severe combined immunodeficiency due to CTPS1 deficiency [PDF]

, 2020
Inserm
openalex   +1 more source

Mechanism and role of regulated cell death in tumor immunity and immunotherapy

Cancer Communications, EarlyView.
Abstract Cancer immune checkpoint inhibitors (ICIs) have brought breakthroughs, but only about one‐third of cancer patients benefit from ICIs. In recent years, targeting non‐apoptotic regulated cell death (RCD) subtypes, such as ferroptosis, necroptosis, autophagy, cuproptosis, and pyroptosis, has emerged as a novel strategy in cancer therapy due to ...
Jingwen Hu, Yan Li, Bingjie Lian, Yitao Mao, Luqing Zhao   +4 more
wiley   +1 more source

Recommendations for the use of the non‐obese diabetic/severe combined immunodeficiency mouse model in autoimmune and drug‐induced thrombocytopenia: communication from the SSC of the ISTH

, 2015
T. Bakchoul, Jens C. Fuhrmann, Beng H. Chong, Daniel W. Bougie, Richard H. Aster   +4 more
openalex   +1 more source

Late presenting atypical severe combined immunodeficiency (SCID) associated with a novel missense mutation in DCLRE1C [PDF]

, 2017
Mikael Sundin, Michael Uhlin, Ahmed Gaballa, Kim Ramme, Antonios G.A. Kolios, Per Marits, Jakob Nilsson   +6 more
openalex   +1 more source

Breaking barriers: the cGAS‐STING pathway as a novel frontier in cancer immunotherapy

Cancer Communications, EarlyView.
Abstract Since its discovery, the cyclic GMP‐AMP synthase (cGAS)‐stimulator of the interferon gene (STING) signaling pathway has been considered a pivotal component of innate immunity and a promising target for cancer immunotherapy. Beyond its canonical role in pathogen defense, accumulating evidence has demonstrated that the cGAS‐STING pathway ...
Yuheng Yan, Ximin Tan, Bin Song, Ming Yi, Qian Chu, Kongming Wu   +5 more
wiley   +1 more source

A serious adverse event after successful gene therapy for X-linked severe combined immunodeficiency.

New England Journal of Medicine, 2003
S. Hacein-Bey-Abina, C. von Kalle, M. Schmidt, F. Le Deist, N. Wulffraat, Elisabeth McIntyre, I. Radford, J. Villeval, C. Fraser, M. Cavazzana‐Calvo, A. Fischer   +10 more
semanticscholar   +1 more source

RNA m1A methyltransferase TRMT61A promotes colorectal tumorigenesis by enhancing ONECUT2 mRNA stability and is a potential therapeutic target

Cancer Communications, EarlyView.
Abstract Background The role of N1‐methyladenosine (m1A) in cancer is poorly understood. Here we explored the function of RNA methyltransferase TRNA methyltransferase 61A (TRMT61A) in colorectal cancer (CRC) and its potential as a therapeutic target. Methods RNA m1A levels were assessed through liquid chromatography‐mass spectrometry.
Xiaoting Zhang, Na Qin, Fenfen Ji, Hao Su, Haiyun Shang, Hongyan Chen, Dan Huang, Qing Li, Jing Ren, Weixin Liu, Yifei Wang, Wei Kang, Jiabin Wu, Chi‐Chun Wong, Zongwei Cai, Matthew Tak Vai Chan, William Ka Kei Wu, Jun Yu, Huarong Chen   +18 more
wiley   +1 more source

Corrigendum: A Novel Homozygous JAK3 Mutation Leading to T-B+NK- SCID in Two Brazilian Patients

Frontiers in Pediatrics, 2018
Lucila A. Barreiros, Gesmar R. S. Segundo, Anete S. Grumach, Pérsio Roxo-Júnior, Troy R. Torgerson, Hans D. Ochs, Antonio Condino-Neto   +6 more
doaj   +1 more source