International Journal of Neonatal Screening, 2017 This review should be seen as a practical tool, one which we hope illustrates potential routes to follow when seeking to implement or lobby for severe combined immunodeficiency newborn screening (SCID NBS) at a national or regional level.
H. Bobby Gaspar
doaj +1 more source
Effect of stem cell source on long-term chimerism and event-free survival in children with primary immunodeficiency disorders after fludarabine and melphalan conditioning regimen [PDF]
, 2016 BACKGROUND: Reduced-intensity conditioning (RIC) regimens are increasingly being used in the transplantation of patients with primary immunodeficiency disorders (PIDs), but there are no large studies looking at long-term lineage-specific chimerism ...
Adams, S +9 more
core
An Atypical Severe Combined Immunodeficiency (SCID) Case Diagnosis Complicated by Alternative Care in the Era of Newborn Screening (NBS) for SCID [PDF]
, 2017 Taylor Alberdi +22 more
openalex +1 more source
Frontiers in Immunology, 2018 Using the CRISPR/Cas9 gene-editing technology, we recently produced a number of rabbits with mutations in immune function genes, including FOXN1, PRKDC, RAG1, RAG2, and IL2RG. Seven founder knockout rabbits (F0) and three male IL2RG null (−/y) F1 animals
Jun Song +18 more
doaj +1 more source
Somatic Cell Therapy: A Genetic Rescue for a Tattered Immune System? [PDF]
, 2012 Étude de cas / Case studyLe cas de M. Andrew Gobea, le premier enfant à recevoir une thérapie génique expérimentale pour le déficience immunitaire combinée sévère (DICS), et une réflexion sur les implications éthiques associées à la recherche en thérapie
Williams-Jones, Bryn
core +1 more source
Severe Combined ImmunoDeficient (SCID) mice in biomedical research
Journal of the Hellenic Veterinary Medical Society, 2017 Mice have been used in cancer research since the last decade of the 19th century. In 1921 inbred strains, that were predisposed to developing tumors, were bred and became available to cancer researchers. The nude mouse, a hairless mutantdiscovered in 1962, is immunodeficient, and thus does not reject tumor transplantations from other species.
openaire +2 more sources
F1000Research, 2017 Severe combined immunodeficiency is a large clinically heterogeneous group of disorders caused by a defect in the development of humoral or cellular immune responses.
Geeta Madathil Govindaraj +11 more
doaj +1 more source
“DISAPPEARING BILE DUCT SYNDROME,” RESULT OF A GRAFT VERSUS HOST (GvsH) REACTION, AFTER FETAL LIVER AND THYMUS TRANSPLANTATION FOR SEVERE COMBINED IMMUNODEFICIENCY DISEASE (SCID) [PDF]
, 1977 Flossie Cohen +4 more
openalex +1 more source
Expectations and experience: Parent and patient perspectives regarding treatment for Severe Combined Immunodeficiency (SCID). [PDF]
Clin Immunol, 2021 Smith H +4 more
europepmc +1 more source
Emergence of CD45RA+ and CD62L+ Blood T Cells in Infants with Severe Combined Immunodeficiency (SCID) Given HLA-Identical or Haploidentical T Cell-Depleted Bone Marrow Stem Cells [PDF]
, 1999 Rebecca H. Buckley
openalex +1 more source