Results 151 to 160 of about 45,777 (283)

Engraftment of Myasthenia Gravis Thymocytes into Severe Combined Immunodeficiency (SCID) Mice

Autoimmunity, 1998
To study the human immune system, thymocytes from myasthenia gravis (MG) patients were transferred into the peritoneal cavity of severe combined immunodeficiency (SCID) mice, which caused the mice to produce human IgG and IgM. The injected thymocytes were then recovered from the peritoneal cavities of MG-SCID mice. The recovered thymocytes were CD3+ or
openaire   +2 more sources

Corrigendum: A Novel Homozygous JAK3 Mutation Leading to T-B+NK- SCID in Two Brazilian Patients

Frontiers in Pediatrics, 2018
Lucila A. Barreiros, Gesmar R. S. Segundo, Anete S. Grumach, Pérsio Roxo-Júnior, Troy R. Torgerson, Hans D. Ochs, Antonio Condino-Neto   +6 more
doaj   +1 more source

The genetic basis of severe combined immunodeficiency and its variants

The Application of Clinical Genetics, 2012
Diana Tasher,1,2 Ilan Dalal1,21The Pediatric Infectious and Immunology Unit, E Wolfson Medical Center, Holon, Israel; 2The Sackler School of Medicine, Tel Aviv University, Tel Aviv, IsraelAbstract: Severe combined immunodeficiency (SCID) syndromes are ...
Tasher D, Dalal I
doaj  

The First Fifty Years of Stem Cell Transplantation in Severe Combined Immunodeficiency (SCID)

Acta Medica Iranica
Since the first successful hematopoietic stem cell transplantation (HSCT) in 1968 for severe combined immunodeficiency (SCID), clinical studies have commenced. However, there is a high heterogeneity across studies. This is a review of studies evaluating
Amene Saghazadeh, Andrew J. Cant, Nima Rezaei   +2 more
doaj   +1 more source

JAMA [PDF]

IMPORTANCENewborn screening for severe combined immunodeficiency (SCID) using assays to detect T-cell receptor excision circles (TRECs) began in Wisconsin in 2008, and SCID was added to the national recommended uniform panel for newborn screened ...

core  

A novel splice variant of the DNA-PKcs gene is associated with clinical and cellular radiosensitvity in a xeroderma pigmentosum patient [PDF]

, 2009
This article has been made available through the Brunel Open Access Publishing Fund.Background: Radiotherapy-induced DNA double strand breaks (DSB) are critical cytotoxic lesions.
Abbaszadeh, F, Arlett, CF, Bourton, EC, Clingen, PH, Green, MHL, Makarov, EM, Newbold, RF, Parris, CN, Plowman, PN, Themis, M   +9 more
core  

Severe combined immunodeficiency (SCID): From the detection of a new mutation to preimplantation genetic diagnosis [PDF]

, 2012
R. Tomashov-Matar, Galia Biran, Irina Lagovsky, Neomi Kotler, Anat Stein, Benjamin Fisch, Onit Sapir, Mordechai Shohat   +7 more
openalex   +1 more source

Development of gene therapy: potential in severe combined immunodeficiency due to adenosine deaminase deficiency

Stem Cells and Cloning: Advances and Applications, 2009
Claudia A Montiel-Equihua, Adrian J Thrasher, H Bobby GasparCentre for Immunodeficiency, Molecular Immunology Unit, UCL Institute of Child Health, London, UKAbstract: The history of stem cell gene therapy is strongly linked to the development of gene ...
Claudia A Montiel-Equihua, Adrian J Thrasher, H Bobby Gaspar   +2 more
doaj  

Adenosine Deaminase (ADA)–Deficient Severe Combined Immune Deficiency (SCID) in the US Immunodeficiency Network (USIDNet) Registry

, 2020
Caroline Y. Kuo, Elizabeth Garabedian, Jennifer M. Puck, Morton J. Cowan, Kathleen E. Sullivan, Rebecca H. Buckley, Charlotte Cunningham‐Rundles, Rebecca Marsh, Fabio Candotti, Donald B. Kohn   +9 more
openalex   +2 more sources

The Effect of Natural Killer Cell Killer Ig-Like Receptor Alloreactivity on the Outcome of Bone Marrow Stem Cell Transplantation for Severe Combined Immunodeficiency (SCID) [PDF]

, 2007
M. D. Keller, D. F. Chen, S. A. Condron, N. Liu, N.L. Reinsmoen, R. H. Buckley   +5 more
openalex   +1 more source