Results 41 to 50 of about 19,116 (219)

Langerhans Cells in Mice with Severe Combined Immunodeficiency (SCID).

Archives of Histology and Cytology, 1996
The existence of Langerhans cells in the stratified squamous epithelium of severely combined immunodeficient (SCID) mice was studied by enzyme histochemistry, immunohistochemistry and electron microscopy. Considerable numbers of ATPase-positive Langerhans cell were observed in the epidermis (ear and hind limb) as well as in the stratified squamous ...
WATANABE, Masanori, KOBAYASHI, Miya, IIDA, Ken-ichi, OZEKI, Masayasu, DOI, Satoru, HOSHINO, Takeshi   +5 more
openaire   +3 more sources

Swiss newborn screening for severe T and B cell deficiency with a combined TREC/KREC assay – management recommendations

Swiss Medical Weekly, 2020
The recent introduction of newborn screening for severe primary T and B cell deficiencies in Switzerland allows rapid identification of patients with severe combined immunodeficiency (SCID). Outcomes for SCID are greatly improved by early diagnosis and
Johannes Trück, Seraina Prader, Giancarlo Natalucci, Cornelia Hagmann, Barbara Brotschi, Janet Kelly, Dirk Bassler, Katharina Steindl, Anita Rauch, Matthias Baumgartner, Ralph Fingerhut, Mathias Hauri-Hohl, Tayfun Güngör, Jana Pachlopnik Schmid, Christoph Berger, Janine Reichenbach   +15 more
doaj   +1 more source

Second-Tier Next Generation Sequencing Integrated in Nationwide Newborn Screening Provides Rapid Molecular Diagnostics of Severe Combined Immunodeficiency

Frontiers in Immunology, 2020
Severe combined immunodeficiency (SCID) and other T cell lymphopenias can be detected during newborn screening (NBS) by measuring T cell receptor excision circles (TRECs) in dried blood spot (DBS) DNA. Second tier next generation sequencing (NGS) with an
Janne Strand, Kiran Aftab Gul, Hans Christian Erichsen, Hans Christian Erichsen, Emma Lundman, Mona C. Berge, Anette K. Trømborg, Linda K. Sørgjerd, Mari Ytre-Arne, Silje Hogner, Ruth Halsne, Ruth Halsne, Hege Junita Gaup, Liv T. Osnes, Grete A. B. Kro, Hanne S. Sorte, Lars Mørkrid, Alexander D. Rowe, Trine Tangeraas, Trine Tangeraas, Jens V. Jørgensen, Jens V. Jørgensen, Charlotte Alme, Trude E. H. Bjørndalen, Arild E. Rønnestad, Astri M. Lang, Terje Rootwelt, Terje Rootwelt, Jochen Buechner, Torstein Øverland, Tore G. Abrahamsen, Tore G. Abrahamsen, Rolf D. Pettersen, Asbjørg Stray-Pedersen, Asbjørg Stray-Pedersen   +34 more
doaj   +1 more source

Neonatal abstinence syndrome is a potential cause of low TREC copy number

Allergy, Asthma & Clinical Immunology, 2021
Severe combined immunodeficiency (SCID) is a rare genetic condition characterized by significant T cell lymphopenia and impaired T cell function. Many jurisdictions use the quantitation of T cell receptor excision circles (TRECs) to screen for SCID in ...
Adil Adatia, Ling Ling, Pranesh Chakraborty, Lauren Brick, Rae Brager   +4 more
doaj   +1 more source

Case Report: A Novel IL2RG Frame-Restoring Rescue Mutation Mimics Early T Cell Engraftment Following Haploidentical Hematopoietic Stem Cell Transplantation in a Patient With X-SCID

Frontiers in Immunology, 2021
Mutations of the interleukin 2 receptor γ chain (IL2RG) result in the most common form of severe combined immunodeficiency (SCID), which is characterized by severe and persistent infections starting in early life with an absence of T cells and natural ...
Jolanda Steininger, Alexander Leiss-Piller, Christoph B. Geier, Raphael Rossmanith, Reem Elfeky, David Bra, Herbert Pichler, Anita Lawitschka, Natascha Zubarovskaya, Gottfried Artacker, Susanne Matthes-Leodolter, Martha M. Eibl, Martha M. Eibl, Hermann M. Wolf, Hermann M. Wolf   +14 more
doaj   +1 more source

Thymic epithelial cells of severe combined immunodeficiency (SCID) mice [PDF]

Journal of Korean Medical Science, 1994
To characterize thymic epithelial cells of SCID (severe combined immunodeficiency) mice in comparison with those of Balb C mice, we did an immunohistochemical study using cortical and medullary epithelial cell specific monoclonal antibodies (MoAbs), Th-3 and Th-4, as well as gel electrophoresis and immunoblotting.
I, Lee, E, Yu, S, Ikehara
openaire   +2 more sources

Postnatal corticosteroid treatment as a risk factor for false positivity in severe combined immunodeficiency newborn screening

Journal of Microbiology, Immunology and Infection, 2023
From 2011, 37 children were referred to a hospital due to low levels of T cell receptor excision circles (TRECs) from newborn screening. Among them, three children were immunologically characterized and followed up to show that postnatal corticosteroid ...
Po-Sung Chen, Ju Lee, Hui-Ping Pan, Yuh-Jyh Lin, Yung-Chieh Lin, Yu-Shan Chang, Yen-Ju Chen, Chia-Liang Yen, Ching-Wei Lin, Chih-An Chen, Chi-Chang Shieh   +10 more
doaj   +1 more source

Clinical and Laboratory Factors Affecting the Prognosis of Severe Combined Immunodeficiency [PDF]

, 2022
Purpose Severe combined immunodeficiency (SCID) is one of the most severe forms of inborn errors of immunity characterized by absence or loss of function in T cells.
Babayeva, Royala, Bulutoglu, Alper, Caki-Kilic, Suar, BARIŞ, SAFA, Kasap, Nurhan, Can, Yasemin, Yesilipek, Akif, Sefer, Asena Pinar, ÖZTÜRK, ELİF, Ozen, Ahmet, Catak, Mehmet Cihangir, Baser, Dilek, Tezcan Karasu, Gulsun, Karakoc-Aydiner, Elif, Nain, Ercan, Yalcin, Koray, Akgun, Gamze, KIYKIM, AYÇA, Bilgic Eltan, Sevgi   +18 more
core   +1 more source

An infant with disseminated bacillus Calmette-Guerin infection (BCGitis)

International Journal of Pediatrics & Adolescent Medicine, 2014
The bacillus Calmette Guerin (BCG) vaccine contains live attenuated Mycobacte-rium bovis bacteria. There is a long-standing controversy surrounding the efficacy of BCG against TB and whether it should be used.
Hamoud Al-Mousa
doaj   +1 more source

Pulmonary Radiological Manifestations of Humoral and Combined Immunodeficiencies in a Tertiary Pediatric Center

Iranian Journal of Allergy, Asthma and Immunology, 2021
Respiratory diseases are considered as significant causes of morbidity and mortality in primary immunodeficiencies. This study aimed to reveal the radiologic patterns of thoracic involvement in these disorders.
Mitra Khalili, Hossein Farzi, Sepideh Darougar, Fatemeh Hajijoo, Mehrnaz Mesdaghi, Mahboubeh Mansouri, Delara Babaie, Amir Hashemitari, Narges Eslami, Zahra Chavoshzadeh   +9 more
doaj   +1 more source