Results 131 to 140 of about 91,699 (304)

Dengue and severe dengue with neurological complications: a challenge for prevention and control

Arquivos de Neuro-Psiquiatria
AbstractDengue is the main urban arbovirus in the Americas. The disease manifests in a varied spectrum: from asymptomatic cases to those with neurological involvement, which is considered a severe form of the disease. Its annual reemergence represents a serious public health problem.
Emanuelle de Oliveira Francelino, Marzia Puccioni-Sohler   +1 more
openaire   +3 more sources

The return of metabolism: biochemistry and physiology of glycolysis

Biological Reviews, EarlyView.
ABSTRACT Glycolysis is a fundamental metabolic pathway central to the bioenergetics and physiology of virtually all living organisms. In this comprehensive review, we explore the intricate biochemical principles and evolutionary origins of glycolytic pathways, from the classical Embden–Meyerhof–Parnas (EMP) pathway in humans to various prokaryotic and ...
Nana‐Maria Grüning, Federica Agostini, Camila Caldana, Johannes Hartl, Matthias Heinemann, Markus A. Keller, Jan Lukas Krüsemann, Costanza Lamperti, Carole L. Linster, Steffen N. Lindner, Julia Muenzner, Jens Nielsen, Zoran Nikoloski, Bettina Siebers, Jacky L. Snoep, Hezi Tenenboim, Bas Teusink, Spencer J. Williams, Mirjam M. C. Wamelink, Markus Ralser   +19 more
wiley   +1 more source

Determinants of Mortality from Severe Dengue in Brazil: A Population-Based Case-Control Study [PDF]

, 2013
Giselle Hentzy Moraes, Eliane de Fátima Duarte, Elisabeth Carmen Duarte   +2 more
openalex   +1 more source

The LGALS9/miR‐491‐5p Axis Regulates CD8+ T Cell Function and Inhibits the Progression of Gastric Cancer

Cancer Science, EarlyView.
In this study, we found that LGALS9 is highly expressed in gastric cancer and may affect the development of gastric cancer by participating in the infiltration of CD8+ T cells. Knockout of LGALS9 can reverse T cell function and relieve immunosuppression, and enhance the killing effect of T cells on gastric cancer cells.
Wanzhong Huang, Wei Zheng, Dagao Zhu, Zhi Sun, Wei Lu, Jun Tao, Chen Liu, Liangliang Li, Yingli Zhou, Honghong Fan, Hong Tao, Wenjuan Li   +11 more
wiley   +1 more source

Pro- and anti-inflammatory cytokines signatures at different severity of dengue infection

Journal of Family Medicine and Primary Care
Context: Dengue disease severity and progression are determined by the host immune response, with both pro- and anti-inflammatory cytokines are key mediators.
Himani Prajapati, Vivek Kumar, Garima Mittal, Yogesh Saxena   +3 more
doaj   +1 more source

重篤なショック，多臓器不全を呈し救命し得なかった重症型デングの1例(A fatal case of severe dengue infection complicated by refractory shock and multiple organ failure) [PDF]

, 2018
遠藤 真佑, 吉田 暁, 熊谷 謙, 廣瀬 保夫, 近藤 大介, 手塚 貴文, 塚田 弘樹   +6 more
openalex   +1 more source

CLEC18A interacts with sulfated glycosaminoglycans and controls clear cell renal cell carcinoma progression

The FEBS Journal, EarlyView.
CLEC18A is a previously poorly characterized C‐type lectin. We mapped the expression of CLEC18A to the proximal tubule of the kidney and found CLEC18A to interact with sulfated glycosaminoglycans on proteoglycans. Furthermore, we found that CLEC18A plays an important role in hindering the progression of clear cell renal cell carcinomas in humans and in
Gustav Jonsson, Maura Hofmann, Stefan Mereiter, Lauren Hartley‐Tassell, Masahiro Onji, Irma Sakic, Tiago Oliveira, David Hoffmann, Maria Novatchkova, Alexander Schleiffer, Josef M. Penninger   +10 more
wiley   +1 more source

Severe COVID-19 multisystem inflammatory syndrome versus severe dengue in children from Indonesia: a cross-sectional study

International Journal of Emergency Medicine
Introduction Severe multisystem inflammatory syndrome in children (MIS-C) and severe dengue are challenging to identify during the COVID-19 pandemic in dengue-endemic areas.
Anggraini Alam, Fina Meilyana Andriyani, Stanza Uga Peryoga   +2 more
doaj   +1 more source

CRISPR‐Enhanced RAA‐SHERLOCK Assay for Point‐of‐Care Detection of Cyprinid Herpesvirus‐3: Development, Validation and Clinical Application

Journal of Fish Diseases, EarlyView.
ABSTRACT Koi herpesvirus disease (KHVD), caused by Cyprinid herpesvirus‐3 (CyHV‐3), poses a significant threat to global aquaculture due to its high mortality rates and economic impact. Current diagnostic methods, such as PCR, are limited by equipment dependency and procedural complexity, hindering point‐of‐care (POC) applications.
Hatem Soliman, Naveed Akram, Mona Saleh
wiley   +1 more source

Structural Design and Immunogenicity of a Novel Self‐Adjuvanting Mucosal Vaccine Candidate for SARS‐CoV‐2 Expressed in Plants

Plant Biotechnology Journal, EarlyView.
ABSTRACT Mucosal vaccination for COVID‐19 to boost preexisting though insufficient systemic and local/mucosal immunity remains an attractive prospect but there are currently no licensed mucosal vaccines against this infection. Here, using a plant expression system, we developed a novel mucosal vaccine platform for respiratory viruses and demonstrated ...
Mi‐Young Kim, Andy Cano Tran, Ju Kim, Humblenoble Stembridge Ayuk, Adam Sparrow, Lorenzo Bossi, Megan Brown, Emil Joseph Vergara, Kathrin Göritzer, Elisabetta Groppelli, Tae‐Ho Kwon, Julian K. C. Ma, Yong‐Suk Jang, Rajko Reljic   +13 more
wiley   +1 more source