Results 131 to 140 of about 327,068 (394)
Biomedicines, 2021 Severe eosinophilic asthma (SEA) is associated with high peripheral blood and airway eosinophilia, recurrent disease exacerbations and severe airflow limitation.
A. Maglio +10 more
semanticscholar +1 more source
The clinical profile of benralizumab in the management of severe eosinophilic asthma [PDF]
Therapeutic Advances in Respiratory Disease, 2016 Despite several therapeutic choices, 10–20% of patients with severe uncontrolled asthma do not respond to maximal best standard treatments, leading to a healthcare expenditure of up to 80% of overall costs for asthma. Today, there are new important therapeutic strategies, both pharmacological and interventional, that can result in improvement of ...
Francesco Menzella +4 more
openaire +4 more sources
Epidemiology of common allergic diseases in China: Current position and implications
Eye &ENT Research, EarlyView.Abstract The prevalence of common allergic diseases, including allergic rhinitis, asthma, atopic dermatitis, and food allergy, has increased dramatically with rising industrialization in China, leading to a significant socio‐economic burden.
Xu Xu +4 more
wiley +1 more source
Omalizumab as alternative to chronic use of oral corticosteroids in severe asthma
, 2019 Systemic/oral corticosteroids (OCS) have been used for decades in the management of acute asthma exacerbations and chronically in patients with uncontrolled severe asthma.
Bousquet, Jean +6 more
core +1 more source
Clinical and Experimental Allergy, 2021 Benralizumab is effective in severe eosinophilic asthma (SEA), but suboptimal responses are observed in some patients. Although several factors have been associated with benralizumab response, no cluster analysis has yet been undertaken to identify ...
D. Di Bona +20 more
semanticscholar +1 more source
Eosinophils Target Therapy for Severe Asthma: Critical Points [PDF]
BioMed Research International, 2018 Asthma is a chronic and heterogeneous disease, which is defined as severe disease whenever it requires treatment with a high dose of inhaled corticosteroids plus a second controller and/or systemic corticosteroids to prevent it from becoming ‘‘uncontrolled’’ or if it remains ‘‘uncontrolled’’ despite this therapy.
Brussino, L. +4 more
openaire +4 more sources
Eye &ENT Research, EarlyView.Abstract IgG4‐related chronic rhinosinusitis (IgG4‐related CRS) is gaining recognition among various specialized physicians. As a systemic disease involving multiple organs, IgG4‐related CRS is still not widely recognized as an independent clinical entity. Given the complexity of diagnosing autoimmune‐related multisystem diseases, early recognition and
Lianqi Wan +3 more
wiley +1 more source
Cellular Mechanisms Underlying Eosinophilic and Neutrophilic Airway Inflammation in Asthma
Mediators of Inflammation, 2015 Asthma is a phenotypically heterogeneous chronic disease of the airways, characterized by either predominant eosinophilic or neutrophilic, or even mixed eosinophilic/neutrophilic inflammatory patterns. Eosinophilic inflammation can be associated with the
Girolamo Pelaia +6 more
doaj +1 more source
Economic evaluation and budgetary burden of mepolizumab in severe refractory eosinophilic asthma [PDF]
Farmacia Hospitalaria, 2019 Objective: Mepolizumab is indicated as an additional treatment of severe refractory eosinophilic asthma. The observed differences in population subgroups according to plasma eosinophil count, the existence of patients with high levels of immunoglobulin
Manuel David Gil-Sierra +4 more
doaj +1 more source
Relationship between Periodontal disease and Asthma among overweight/obese adults [PDF]
arXiv, 2016 Aim: To assess the relationship between oral health and asthma. Methods: Data from 1,315 overweight or obese individuals, aged 40-65 years was used. Asthma was self-reported, while periodontitis, bleeding on probing (BOP), and plaque index were determined by clinical examinations. Results: Using logistic regression adjusting for gender, smoking status,
arxiv