Results 221 to 230 of about 327,068 (394)

Severe eosinophilic asthma in Chinese C‐BIOPRED asthma cohort [PDF]

Clinical and Translational Medicine, 2022
Qingling Zhang, Xiuhua Fu, Changzheng Wang, Huahao Shen, Lei Zhu, Guochao Shi, Zhongmin Qiu, Zhongguang Wen, Wei Gu, Wei Luo, Lina Zhao, Yunqin Chen, Sam Lim, Chang Xiao, Jian Kang, Yunhui Zhang, Mao Huang, Jinfu Xu, Kewu Huang, Qiang Li, Xiangyan Zhang, Jianping Zhao, Xiaoxia Liu, Shenghua Sun, Huaping Tang, Bei He, Shaoxi Cai, Ping Chen, Chunhua Wei, Guangfa Wang, Ping Chen, Lixin Xie, Jiangtao Lin, Yuling Tang, Zhihai Han, Kian Fan Chung, Nanshan Zhong, the C‐BIOPRED consortium   +37 more
openaire   +3 more sources

Clinical and Biological Remission With Tezepelumab: The Real‐World Response in Severe Uncontrolled Asthma

Allergy, EarlyView.
This study analyzed the clinical and biomarker data from 175 adults with severe asthma treated with the anti‐TSLP monoclonal antibody tezepelumab. Following tezepelumab initiation, the exacerbation rate decreased, with 59% of patients remaining exacerbation‐free at 1 year. Asthma symptom control as measured by ACQ‐6 significantly improved after 4 weeks
Jessica Gates, Faizan Haris, Francesca Cefaloni, Paniz Khooshemehri, Linda Green, Mariana Fernandes, Louise Thomson, Cris Roxas, Jodie Lam, Grainne d'Ancona, Alexandra M. Nanzer, Jaideep Dhariwal, David J. Jackson   +12 more
wiley   +1 more source

P203 Effectiveness of anti-IL4R therapy following Suboptimal Response to anti-IL5/5R therapy in severe eosinophilic asthma [PDF]

, 2021
TW Mason, AP Hearn, Gianmarco D’Ancona, M Fernandes, C Roxas, L Green, Louise Thomson, Jaideep Dhariwal, AM Nanzer, DJ Jackson   +9 more
openalex   +1 more source

Economic Impact of Allergic Diseases and Asthma—The HEAD Pan‐European Registry

Allergy, EarlyView.
This registry‐based study demonstrates the substantial economic burden of allergic diseases across Europe with a high degree of heterogeneity between countries. Treatments and specialist visits are the primary drivers of healthcare costs. Asthma poses the highest disease burden.
Ioana Agache, Maria Torres, Ibon Eguiluz‐Gracia, Elena Bradatan, Kamal El Abd, Maria Beatrice Bilo, Federica Rivolta, Andrea Sangalli, Roxana Bumbacea, Selda Ali, Dario Antolin, Águeda Concepción Lario Cuenda, Vicente Albéndiz, Maria Miguel Oliveira, Paulo Jorge Nogueira, Loreto Carmona, HEAD Study Group, Audrey Courtois, Helene Simonis, Romain Nonis, Michel Crine, Christine Leon, Carine Sohy, Virgine Doyen, Andre Benedicte, Charles Pilette, Irina Kaidalina, Christophe Goubau, Katerina Absolonova, Ales Zlamal, Olga Zlamalova, Phillip Globig, Margitta Worm, Angelika Sasien, Mehrak Yoosefi Moridani, Federica Rivolta, Valentina Longo, Andrea Sangalli, Francesco Murzilli, Carmela Montera, Mario Lo Schiavo, Corina Bocsan, Corina Ureche, Cristian Budica, Diana Deleanu, Adriana Muntean, Agnes Sandor, Carmen Teodora Dorican, Camelia Berghea, Florin‐Dan Popescu, Irina Bucur, Mariana Vieru, Laia Ferré, Alicia Habernau, Agueda Larios, Jose Julio Laguna, Natalia Pérez Sánchez, Oscar Asensio, Roser Ayats, Helena Larramona, Beatriz Torres‐Pérez, Alica Barra‐Castro, Sergio Quevedo, Teresa Bracamonte, Manuel Diaz, Miguel Tortajada, Dah Tay Jang   +66 more
wiley   +1 more source

P9‐62: Effectiveness of benralizumab for severe eosinophilic asthma [PDF]

, 2021
Takatomo Hirouchi, Norio Kodaka, Chihiro Nakano, Takeshi Oshio, Kayo Watanabe, Kumiko Niitsuma, Hirotsugu Morita, Yuka Yamada, Manabu Sato, Masato Moroi, Toshiaki Oharazeki, Hiroto Matsuse   +11 more
openalex   +1 more source

Dupilumab Treatment Is Associated With Clinical Improvement and a Shift Toward a Health‐Associated Nasal Passage Microbiota in Diffuse Type 2 Chronic Rhinosinusitis

Allergy, EarlyView.
This study investigates longitudinal effects of dupilumab on the nasal passage and gastrointestinal microbiota in patients with diffuse type 2 CRSwNP. CRSwNP patients show altered nasal microbiota composition compared to healthy individuals. Dupilumab treatment is associated with a shift of nasal microbiota in CRSwNP, with increasing beneficial genera (
Fabio S. Ryser, Tomas Demeter, Judith Bergada Pijuan, Srikanth Mairpady Shambat, Catrin Brühlmann, Tina Mauthe, Markus Hilty, Michael B. Soyka, Urs C. Steiner, Silvio D. Brugger   +9 more
wiley   +1 more source

Systematic Review of Real-World Effectiveness and Safety Studies of Mepolizumab in Treating Severe Eosinophilic Asthma [PDF]

, 2021
Elliot Israel, G.W. Canonica, G.G. Brusselle, S. Yang, P. Howarth, A. Martin, M. Koufopoulou, Steven G. Smith, R. Alfonso Cristancho   +8 more
openalex   +1 more source

Basophil Activation Test: Bridging Allergy and Oncology for Diagnostic, Therapeutic and Prognostic Applications in AllergoOncology: An EAACI Position Paper

Allergy, EarlyView.
ABSTRACT The basophil activation test (BAT) is gaining increasing relevance as an ex vivo functional assay in allergy to evaluate IgE‐mediated hypersensitivity reactions to food allergens, venoms, and drugs and to monitor tolerance induction. Establishing universal standard operating protocols has been difficult, due to several challenges including ...
Mariona Pascal, Jitesh Chauhan, Edward Knol, Rodolfo Bianchini, Mariana Castells, Leticia De las Vecillas, Karin Hartmann, Elena Izquierdo, Uta Jappe, Teodorikez‐Wilfox Jimenez‐Rodriguez, Francesca Levi‐Schaffer, Cristobalina Mayorga, Aurélie Poli, Frank Redegeld, Alexandra F. Santos, Erika Jensen‐Jarolim, Christoph Bergmann, Sophia N. Karagiannis, Heather J. Bax   +18 more
wiley   +1 more source

The role of individual characteristics of human subjects on the radiation burden of the bronchial airways from radon progeny [PDF]

arXiv
Variability in radiation-related health risk and genetic susceptibility to radiation effects within a population is a key issue for radiation protection. Besides differences in the health and biological effects of the same radiation dose, individual variability may also affect dose distribution and its consequences for the same exposure. As exposure to
arxiv  

Dupilumab for bullous pemphigoid with intractable pruritus [PDF]

, 2019
Bullous pemphigoid (BP) is an autoimmune blistering disorder that predominantly affects the elderly. Treatment regimens typically include topical and systemic immunosuppressive medications.
Eichenfield, Dawn Z, Orme, Charisse M, Seidman, Jason S   +2 more
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