Results 81 to 90 of about 37,820 (304)

What's new in the diagnosis and management of food allergy in children? [PDF]

open access: yes, 2013
This article reviews the recent advances in the diagnosis and management of IgE mediated food allergy in children. It will encompass the emerging technology of component testing; moves to standardization of the allergy food challenge; permissive diets ...
Campbell, DE, Turner, PJ
core   +1 more source

Eosinophils Target Therapy for Severe Asthma: Critical Points [PDF]

open access: yesBioMed Research International, 2018
Asthma is a chronic and heterogeneous disease, which is defined as severe disease whenever it requires treatment with a high dose of inhaled corticosteroids plus a second controller and/or systemic corticosteroids to prevent it from becoming ‘‘uncontrolled’’ or if it remains ‘‘uncontrolled’’ despite this therapy.
Brussino, L.   +4 more
openaire   +3 more sources

Lung maneuvers of large amplitudes for probing physiological alterations in mouse models of asthma

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Lung maneuvers of small amplitudes, such as the ones performed in oscillometry, are the current gold standard to probe lung mechanics in animals, but they are insensitive to detect baseline physiological alterations in mouse models of asthma. Herein, lung maneuvers of different amplitudes were compared in two mouse models of asthma.
Magali Boucher   +4 more
wiley   +1 more source

Severe eosinophilic asthma in Chinese C‐BIOPRED asthma cohort [PDF]

open access: yesClinical and Translational Medicine, 2022
Qingling Zhang   +37 more
openaire   +3 more sources

Multi‐omics data mining combined with experimental validation reveals ferroptosis‐ and autophagy‐associated hub genes as diagnostic candidates and immune modulators in atherosclerosis

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Using the GSE225650 dataset, we performed differential expression gene (DEG) screening, Weighted Gene Coexpression Network Analysis (WGCNA), and immune infiltration profiling on atherosclerosis (AS) samples, yielding 104 shared candidate genes. Subsequently, these 104 candidate genes were intersected with ferroptosis‑ and autophagy‑related gene sets ...
Xinou Zheng   +6 more
wiley   +1 more source

Aerodigestive evaluation in patients with eosinophilic asthma

open access: yesRespiratory Medicine Case Reports
We present two pediatric patients with severe uncontrolled asthma who underwent aerodigestive evaluation revealing eosinophilic asthma and eosinophilic esophageal inflammation.
Chloe Citron   +4 more
doaj   +1 more source

Self-assembling nanoparticles containing dexamethasone as a novel therapy in allergic airways inflammation. [PDF]

open access: yes, 2013
Nanocarriers can deliver a wide variety of drugs, target them to sites of interest, and protect them from degradation and inactivation by the body. They have the capacity to improve drug action and decrease undesirable systemic effects.
Bratt, Jennifer M   +6 more
core   +2 more sources

Myo‐Inositol Mitigates Oxidative Stress in Bovine Mammary Epithelial Cells via Activation of the SIRT5/Nrf2 Signaling Axis

open access: yesAnimal Research and One Health, EarlyView.
Myo‐inositol alleviates oxidative stress in dairy cow mammary epithelial cells via the Sirt5/Nrf2 pathway to promote mitochondrial fusion. This graphical abstract was created with BioRender.com. ABSTRACT High‐yielding dairy cows are susceptible to mammary gland oxidative stress due to prolonged intensive lactation, leading to redox imbalance.
Yufei Zhang   +8 more
wiley   +1 more source

The Comparative Effectiveness of Mepolizumab and Benralizumab in the Treatment of Eosinophilic Asthma

open access: yesAdvances in Respiratory Medicine
Background: Severe asthma is associated with significant morbidity and risk of complications. Some patients, suffering from eosinophilic asthma, may benefit from biological therapies, especially anti IL-5 (anti-interleukin-5).
Aleksandra Niemiec-Górska   +6 more
doaj   +1 more source

Severe bronchial asthma in children with exercise-induced bronchospasm [PDF]

open access: yes, 2017
Based on a complex examination 46 of schoolchildren suffering from severe asthma, we established that greater proportion of schoolchildren with exercise-induced asthma was with symptoms of mucospin hypereosinophilia (average content of eosinophilic ...
Basіuk, N.V.   +3 more
core  

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