Characterization of Glycoprotein-Mediated Entry of Severe Fever with Thrombocytopenia Syndrome Virus [PDF]
ABSTRACT Severe fever with thrombocytopenia syndrome (SFTS) is an emerging hemorrhagic fever with a high case fatality rate caused by SFTS virus (SFTSV). Effective vaccines and specific therapies for SFTS are urgently sought, and investigation into virus-host cell interactions is expected to contribute to the development of antiviral ...
Aiko Fukuma+7 more
openaire +3 more sources
Novel Coronavirus COVID-19 Strike on Arab Countries and Territories: A Situation Report I [PDF]
The novel Coronavirus (COVID-19) is an infectious disease caused by a new virus called COVID-19 or 2019-nCoV that first identified in Wuhan, China. The disease causes respiratory illness (such as the flu) with other symptoms such as a cough, fever, and in more severe cases, difficulty breathing.
arxiv
Cross-genotype protection of live-attenuated vaccine candidate for severe fever with thrombocytopenia syndrome virus in a ferret model [PDF]
Severe fever with thrombocytopenia syndrome (SFTS) virus (SFTSV) is an emerging tick-borne virus classified within the Banyangvirus genus. SFTS disease has been reported throughout East Asia since 2009 and is characterized by high fever, thrombocytopenia,
Brennan, Benjamin+7 more
core +1 more source
European Guideline (EuroGuiDerm) on atopic eczema: Living update
The updated guideline includes a new evidence‐based recommendation for the IL‐13 inhibitor lebrikizumab. In addition, the Janus kinase inhibitors baricitinib and abrocitinib, which were initially only approved for adult patients, are now also recommended for children from the age of 2 and adolescents from the age of 12, respectively.
A. Wollenberg+31 more
wiley +1 more source
Effects of APOBEC3G on the replications of severe fever with thrombocytopenia syndrome virus
Objective To study the effect of apolipoprotein B mRNA editing enzyme catalytic subunit 3G (APOBEC3G)on virus replication and IL-6 production during severe fever with thrombocytopenia syndrome virus (SFTSV) infection.
Yanixn TAO+5 more
doaj +1 more source
Viral shedding pattern of severe fever with thrombocytopenia syndrome virus in severely ill patients: A prospective, Multicenter cohort study. [PDF]
Hu LF+15 more
europepmc +2 more sources
Coronavirus SARS-CoV-2: Analysis of subgenomic mRNA transcription, 3CLpro and PL2pro protease cleavage sites and protein synthesis [PDF]
Coronaviruses have recently caused world-wide severe outbreaks: SARS (Severe Acute Respiratory Syndrome) in 2002 and MERS (Middle-East Respiratory Syndrome) in 2012. At the end of 2019, a new coronavirus outbreak appeared in Wuhan (China) seafood market as first focus of infection, becoming a pandemics in 2020, spreading mainly into Europe and Asia ...
arxiv
Viral infection triggers monomerization and nuclear translocation of the salicylic acid receptor NONEXPRESSOR OF PATHOGENESIS‐RELATED GENES1 (NPR1) to activate pathogenesis‐related gene expression. Nevertheless, viruses have developed one or more proteins to target NPR1 and impair its functionality through mechanisms such as inducing its degradation ...
Xue Jiang+9 more
wiley +1 more source
COVID-Datathon: Biomarker identification for COVID-19 severity based on BALF scRNA-seq data [PDF]
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emergence began in late 2019 and has since spread rapidly worldwide. The characteristics of respiratory immune response to this emerging virus is not clear. Recently, Single-cell RNA sequencing (scRNA-seq) transcriptome profiling of Bronchoalveolar lavage fluid (BALF) cells has been done ...
arxiv
Emerging tick-borne infections in mainland China: an increasing public health threat [PDF]
Since the beginning of the 1980s, 33 emerging tick-borne agents have been identified in mainland China, including eight species of spotted fever group rickettsiae, seven species in the family Anaplasmataceae, six genospecies in the complex Borrelia ...
Cao, Wu-Chun+17 more
core +1 more source