Results 211 to 220 of about 3,150,561 (392)
The 15‐Year Survival Advantage: Immune Resilience as a Salutogenic Force in Healthy Aging
Human aging shows puzzling diversity: similar aging rates yet vastly different health outcomes. Our study of ~17,500 people revealed a health‐promoting trait (more common in women) linked to strong immune resilience and high expression of TCF7, a key immune gene. This trait enables individuals to fight infections like COVID‐19 more effectively, respond
Muthu Saravanan Manoharan+176 more
wiley +1 more source
Opportunities and Challenges of Population Pharmacogenomics
ABSTRACT Pharmacological responses can vary significantly among patients from different ethnogeographic backgrounds. This variability can, at least in part, be attributed to population‐specific genetic patterns in genes involved in drug absorption, distribution, metabolism, and excretion, as well as in genes associated with drug‐induced toxicity ...
Yitian Zhou+3 more
wiley +1 more source
HIGH INCIDENCE OF SEVERE PARASITEMIA IN FALCIPARUM MALARIA [PDF]
Deepak Rosha, VK Kataria, KK MAUDAR
openalex +1 more source
Cytoadherence and severe malaria.
Malaria is a disease that causes enormous human morbidity and mortality. One feature of mature Plasmodium falciparum-infected erythrocytes leading to the development of severe malaria is thought to be cytoadherence and blockage of the microvasculature. Therefore, an understanding of mechanisms that mediate parasite adhesion leading to malaria pathology
Craig, Alister G.+2 more
openaire +1 more source
ABSTRACT Generalised Granuloma Annulare (GGA) is a chronic inflammatory skin disorder with no standard treatment. Since the last review in 2013, new treatments and varied responses have highlighted the need for an updated synthesis to guide clinical decisions.
Luca Bettolini+11 more
wiley +1 more source
A non-sense mutation and protection from severe malaria [PDF]
Stephen J. Rogerson+2 more
openalex +3 more sources
"The Impact of Malaria Eradication on Fertility" [PDF]
The malaria eradication campaign that started in Sri Lanka in the late 1940s virtually eliminated malaria transmission on the island. I use the pre-eradication differences in malaria endemicity within Sri Lanka to identify the effect of malaria ...
Adrienne M. Lucas
core
Abstract Instrumental variable (IV) analysis relies on the exclusion restriction—that the instrument only affects the dependent variable via its relationship with the independent variable and not via other causal routes. However, scholars generally justify the exclusion restriction based on its plausibility.
Jonathan Mellon
wiley +1 more source
La femme fait la maison: The Accumulation of Surplus Value through Family Planning in Burkina Faso1
Abstract Since the 1960s, demographers, international donors, and governments have calculated the political, economic, and social benefits of modern contraception usage in West Africa. We evidence how family planning technologies (FPTs) that are tethered to population development extract double value (productive and reproductive labour) from Burkinabè ...
T.D. Harper‐Shipman, Katian Napon
wiley +1 more source
Background & objectives: Many host genetic factors are associated with the disease severity and fatal outcome of falciparum malaria. CD40L gene has been found to be one of the most important factors associated with malaria in African countries.
Prasanta Purohit+5 more
doaj