Results 91 to 100 of about 2,639,603 (318)

IMPROVING ROAD SAFETY: SUPERVISED MACHINE LEARNING ANALYSIS OF FACTORS INFLUENCING CRASH SEVERITY [PDF]

Scientific Journal of Silesian University of Technology. Series Transport
Road traffic crash severity is shaped by a complex interplay of human, vehicular, environmental, and infrastructural factors. While machine learning (ML) has shown promise in analyzing crash data, gaps remain in model interpretability and region-specific
Khanh Giang LE
doaj   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source

Vegetation response to a short interval between high-severity wildfires in a mixed-evergreen forest

, 2009
1 Variations in disturbance regime strongly influence ecosystem structure and function. A prominent form of such variation is when multiple high-severity wildfires occur in rapid succession (i.e. short-interval (SI) severe fires, or ‘re-burns’).
Kauffman, J.B., Fontaine, J.B., Law, B.E., Robinson, W.D., Donato, D.C.   +4 more
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Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Severity and death

Medicine, Health Care and Philosophy
AbstractThis article discusses the relationship between two theories about the badness of death, the Life-Comparative Account and the Gradualist Account, and two methods of operationalizing severity in health care priority setting, Absolute Shortfall and Proportional Shortfall.
openaire   +3 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Gastroenterological Surgery and Management of Clostridioides difficile Infection: A Review

Journal of the Anus, Rectum and Colon
Fever and diarrhea are the common symptoms of Clostridioides difficile infection (CDI); however, pseudomembranous enteritis, megacolonization, and paralytic ileus have been observed in severe cases. C.
Tomonori Takano, Hiroyuki Aiba, Mitsuo Kaku, Hiroyuki Kunishima   +3 more
doaj   +1 more source

Aplicação do silício para aumentar a resistência do arroz à mancha-parda Silicon application to increase rice resistance to brown spot

Pesquisa Agropecuária Brasileira, 2009
O objetivo deste trabalho foi avaliar fontes e métodos de aplicação de silício para aumentar sua absorção e a resistência de plantas de arroz (Oryza sativa), cultivar Metica-1, à mancha-parda (Bipolaris oryzae). Foram conduzidos dois experimentos em casa
Luiz Antônio Zanão Júnior, Renildes Lúcio Ferreira Fontes, Vinícius Tavares de Ávila   +2 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Efficient Mortgage Default Option Exercise: Evidence from Loss Severity [PDF]

This paper extends options-based mortgage default theory to include transaction costs. When transaction costs are considered, the rational borrower will default only when the value of the collateral falls below the mortage value by an amount equal to the
Gordon W. Crawford, Eric Rosenblatt
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