Results 81 to 90 of about 2,639,603 (318)

Severity assessment of roadside tree accidents based on occupant injuries analysis

open access: yes, 2020
To achieve the quantitative assessment of roadside tree accident severity on highways, corresponding safety measures were proposed to reduce accident ...
Cheng, Severity assessment of roadside tree accidents based on occupant injuries analysis DOCTOR (Northeast Forestry University), Researcher
core   +1 more source

Integrated single-cell chromatin and transcriptomic analyses of peripheral immune cells in patients with alopecia areata

open access: yesFrontiers in Immunology
IntroductionAlopecia areata (AA) is an autoimmune disorder characterized by non-scarring hair loss ranging from mild, self-limiting episodes to severe and chronic forms.
Jesus Gay-Mimbrera   +18 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

A comparison of severity of illness scoring systems for intensive care unit patinets: Results of a multicenter, multination study

open access: yes, 1995
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Kari A.   +6 more
core  

Association of the Severity of Alopecia With the Severity of Ichthyosis [PDF]

open access: yesJAMA Dermatology, 2019
Elana, Putterman   +4 more
openaire   +2 more sources

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

The new Global Multiple Sclerosis Severity Score (MSSS) correlates with axonal but not glial biomarkers

open access: yes, 2006
This study investigated whether the new Global Multiple Sclerosis Severity Scale (MSSS) correlated with cerebrospinal fluid biomarkers for axonal and glial pathology.
Polman, C.H.   +6 more
core  

Impact of COVID-19 pandemic on the etiology and severity of respiratory viral infections in children

open access: yesВопросы вирусологии
Objective. To analyze the age-related characteristics of the contribution of influenza viruses, RSV, SARS-CoV-2, other pathogens to the development of severe acute respiratory infections (SARI) in children with an assessment of the disease severity ...
Anna А. Sominina   +20 more
doaj   +1 more source

Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila

open access: yesFEBS Letters, EarlyView.
Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia   +6 more
wiley   +1 more source

Clinical characteristics of pertussis during the period of rising incidence

open access: yesЖурнал инфектологии
Objective: in the context of a new epidemiological situation, assess the severity of the course of pertussis and the formation of complicated forms in patients of all ages hospitalized in GBUZ IKB No. 1 DZM (Moscow).Materials and methods.
M. S. Petrova   +6 more
doaj   +1 more source

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