Sevoflurane is one of the most commonly used volatile anaesthetics for children, but the safety of prolonged or repeated clinical use of sevoflurane in infants or children is controversial.
Fu-Yi Shen +13 more
doaj +1 more source
Pharmacokinetics, absolute bioavailability and tolerability of ketamine after intranasal administration to dexmedetomidine sedated dogs [PDF]
Intranasal ketamine has recently gained interest in human medicine, not only for its sedative, anaesthetic or analgesic properties, but also in the management of treatment resistant depression, where it has been shown to be an effective, fast acting ...
Croubels, Siska +6 more
core +1 more source
Research progress on the depth of anesthesia monitoring based on the electroencephalogram
Electroencephalogram (EEG) can noninvasive, continuous, and real‐time monitor the state of brain electrical activity, and the monitoring of EEG can reflect changes in the depth of anesthesia (DOA). The development of artificial intelligence can enable anesthesiologists to extract, analyze, and quantify DOA from complex EEG data.
Xiaolan He, Tingting Li, Xiao Wang
wiley +1 more source
Hypothermia and postconditioning after cardiopulmonary resuscitation reduce cardiac dysfunction by modulating inflammation, apoptosis and remodeling [PDF]
Background: Mild therapeutic hypothermia following cardiac arrest is neuroprotective, but its effect on myocardial dysfunction that is a critical issue following resuscitation is not clear.
Albrecht, Martin +9 more
core +3 more sources
Abstract Objectives Vascular anomalies can cause extrinsic esophageal compression, leading to dysphagia or feeding difficulties in children. Diagnosis typically relies on imaging and endoscopy, which may under‐ or overestimate functional narrowing. Endoluminal functional lumen imaging probe (EndoFLIP) provides luminal parameters in real‐time, but its ...
Brett J. Hoskins +2 more
wiley +1 more source
Mechanisms of Volatile Anesthetic-Induced Myocardial Protection [PDF]
Volatile anesthetics protect myocardium against reversible and irreversible ischemic injury. Experimental evidence from several in vitro and in vivo animal models demonstrates that volatile agents enhance the recovery of stunned myocardium and reduce the
Gu, Weidong +6 more
core +1 more source
Accurate molecular imaging of small animals taking into account animal models, handling, anaesthesia, quality control and imaging system performance [PDF]
Small-animal imaging has become an important technique for the development of new radiotracers, drugs and therapies. Many laboratories have now a combination of different small-animal imaging systems, which are being used by biologists, pharmacists ...
Bankstahl, Jens +5 more
core +1 more source
Overnight Monitoring After T&A for Children Ages 24–36 Months: Is It Always Necessary?
This study aims to identify whether all children < 3 years of age require overnight admission after tonsillectomy with or without adenoidectomy. We found that 98.7% of children who were off oxygen within 3 h after surgery never went back on oxygen during the entire monitoring period.
Tyler Van Heest +4 more
wiley +1 more source
Sevoflurane Increases Hippocampal Theta Oscillations and Impairs Memory Via TASK-3 Channels
Sevoflurane can induce memory impairment during clinical anesthesia; however, the underlying mechanisms are largely unknown. TASK-3 channels are one of the potential targets of sevoflurane.
Linlin Han +9 more
doaj +1 more source
ABSTRACT Background Preoperative Anxiety in Young Children Is Common and Can Lead to Adverse Outcomes. In Clinical Routine, Anesthesiologists Must Often Predict Anxiety Based on Limited Interaction. Aims This study aimed to evaluate the accuracy of early anxiety predictions and to identify early predictors of heightened anxiety at anesthesia induction.
Armin Sablewski +7 more
wiley +1 more source

