Results 61 to 70 of about 85,306 (297)

Anesthesia in the surgery of strabismus: role of anesthetic agents in the ocular deviation and surgical outcome [PDF]

, 2015
Purpose: To determine whether the changes in the ocular alignment following general anesthesia, maintained with two different inhalational anesthetic agents, sevoflurane and desflurane, can be used as a predictor for surgical outcomes in children with ...
Arrico, Loredana, Cannata, Riccardo, Collini, Saul, Malagola, Romualdo, Migliorini, Raffaele, Servidio, Annalisa   +5 more
core   +1 more source

Estrogen Alleviates Sevoflurane‐Induced Neurotoxicity by Inhibiting ERα‐Tau Binding

Advanced Science, EarlyView.
Sevoflurane‐induced neurotoxicity exhibits sex differences, and estrogen can mitigate these effects; however, its protective action appears to be time‐window dependent, which may be related to the competitive binding of estrogen and Tau to ERα. Abstract Sevoflurane‐induced neurotoxicity is age‐dependent, but the role of sex differences is unclear ...
Feixiang Li, Bingqing Gong, Zichen Song, Nuo Yang, Yuming Liu, Jinqin Zhang, Dujuan Li, Yongyan Yang, Yonghao Yu   +8 more
wiley   +1 more source

Sevoflurane Does Not Promote the Colony-Forming Ability of Human Mesenchymal Glioblastoma Stem Cells In Vitro

Medicina, 2022
Background and Objectives: Clinically used concentrations of sevoflurane, an inhaled anesthetic, have been reported to significantly inhibit tumor growth.
Tomohiro Shoji, Mikio Hayashi, Chisato Sumi, Munenori Kusunoki, Takeo Uba, Yoshiyuki Matsuo, Kiichi Hirota   +6 more
doaj   +1 more source

Tracheal intubation without neuromuscular blocking drugs in children [PDF]

, 2009
No abstract ...
Aantaa, Abdallah, Aouad, Batra, Blair, Blair, Bode, Crawford, De Fatima De Assuncao Braga, Drenger, Duman, Gupta, Hansen, Hansen, Helbo-Hansen, Hiller, Humphries, Inomata, Inomata, Inomata, Inomata, Inomata, Klemola, Lerman, Meakin, Mertes, Min, Morgan, Nishina, O’Brien, Politis, Politis, Robinson, Senel, Simon, Splinter, Steyn, Swan, Taguchi, Thwaites, Wappler, Warner, Watcha, Watcha, Watcha, Watcha, Weber, Woods, Xue, Xue, Xue, Xue, Yaguchi   +52 more
core   +1 more source

Mitochondrial CISD1 Modulates Microglial Metabolic Reprogramming to Drive Stress Susceptibility in Mice

Advanced Science, EarlyView.
CDGSH iron sulfur domain 1 (CISD1) mitigates oxidative stress by promoting NADH oxidation and Coenzyme Q (CoQ) reduction. Under chronic stress, elevated CISD1 expression in microglia enhances NAD⁺ production, thereby increasing GAPDH activity and glycolytic flux, while reducing ATP synthesis by inhibiting proton transfer from mitochondrial complexes I ...
Wanting Dong, Duo Liu, Songsen Fu, Jiaming Zhang, Xi Chen, Songqiang Huang   +5 more
wiley   +1 more source

Mechanisms of Volatile Anesthetic-Induced Myocardial Protection [PDF]

, 2003
Volatile anesthetics protect myocardium against reversible and irreversible ischemic injury. Experimental evidence from several in vitro and in vivo animal models demonstrates that volatile agents enhance the recovery of stunned myocardium and reduce the
Gu, Weidong, Kersten, Judy R., LaDisa, John F., Ludwig, Lynda M., Pagel, Paul S., Tanaka, Katsuya, Warltier, David C.   +6 more
core   +1 more source

Pharmacokinetics, absolute bioavailability and tolerability of ketamine after intranasal administration to dexmedetomidine sedated dogs [PDF]

, 2020
Intranasal ketamine has recently gained interest in human medicine, not only for its sedative, anaesthetic or analgesic properties, but also in the management of treatment resistant depression, where it has been shown to be an effective, fast acting ...
Croubels, Siska, Devreese, Mathias, Dockx, Robrecht, Duchateau, Luc, Peremans, Kathelijne, Polis, Ingeborgh, Vlerick, Lise   +6 more
core   +1 more source

Sevoflurane Inhibits Metastasis in Hepatocellular Carcinoma by Inhibiting MiR-665-Induced Activation of the ERK/MMP Pathway

Cell Transplantation, 2022
Recent evidence has indicated that inhalational anesthetics may affect the growth and malignant potential of tumor cells and ultimately influence tumor recurrence after surgery.
Xiaoyan Zhu, Chuchu Peng, Zhiyong Peng, Ruimin Chang, Qulian Guo   +4 more
doaj   +1 more source

Hypothermia and postconditioning after cardiopulmonary resuscitation reduce cardiac dysfunction by modulating inflammation, apoptosis and remodeling [PDF]

, 2009
Background: Mild therapeutic hypothermia following cardiac arrest is neuroprotective, but its effect on myocardial dysfunction that is a critical issue following resuscitation is not clear.
Albrecht, Martin, Bein, Berthold Helmut, Grünewald, Matthias Lars, Koch, Alexander, Lucius, Ralph, Meybohm, Patrick, Scholz, Jens, Tran, Thi Hoai Nguyen, Zacharowski, Kai, Zitta, Karina   +9 more
core   +3 more sources

Delta oscillations phase limit neural activity during sevoflurane anesthesia

Communications Biology, 2019
Understanding anesthetic mechanisms with the goal of producing anesthetic states with limited systemic side effects is a major objective of neuroscience research in anesthesiology.
Shubham Chamadia, J. Pedemonte, Eunice Y. Hahm, Jennifer Mekonnen, R. Ibala, Jacob Gitlin, Breanna R. Ethridge, J. Qu, Rafael Vazquez, James Rhee, Erika T. Liao, E. Brown, O. Akeju   +12 more
semanticscholar   +1 more source