Results 11 to 20 of about 3,070,104 (291)
Sex Bias in Asthma Prevalence and Pathogenesis [PDF]
Frontiers in Immunology, 2018 Sex-related differences in asthma prevalence are well established and change through the reproductive phases of life. As children, boys have increased prevalence of asthma compared to girls.
Ruchi Shah +2 more
doaj +3 more sources
Addressing Ancestry and Sex Bias in Pharmacogenomics
Annual Review of Pharmacology and ToxicologyThe association of an individual's genetic makeup with their response to drugs is referred to as pharmacogenomics. By understanding the relationship between genetic variants and drug efficacy or toxicity, we are able to optimize pharmacological therapy according to an individual's genotype. Pharmacogenomics research has historically suffered from bias
Corpas, M +5 more
openaire +4 more sources
Frontiers in Immunology, 2021 Multiple Sclerosis (MS) is a complex immune-mediated disease of the central nervous system. Treatment is based on immunomodulation, including specifically targeting B cells.
Jeremy T. Keane +8 more
doaj +1 more source
Sex-Biased Expression of Pharmacogenes across Human Tissues
Biomolecules, 2021 Individual response to drugs is highly variable and largely influenced by genetic variants and gene-expression profiles. In addition, it has been shown that response to drugs is strongly sex-dependent, both in terms of efficacy and toxicity.
Maria Laura Idda +7 more
doaj +1 more source
Frontiers in Sports and Active Living, 2022 BackgroundTo combat historical underrepresentation of female participants in research, guidelines have been established to motivate equal participation by both sexes.
Lindsay A. Lew +5 more
doaj +1 more source
Gene-Specific Sex Effects on Susceptibility to Infectious Diseases
Frontiers in Immunology, 2021 Inflammation is an integral part of defense against most infectious diseases. These pathogen-induced immune responses are in very many instances strongly influenced by host’s sex.
Marie Lipoldová, Peter Demant
doaj +1 more source
Sex bias in autoimmunity [PDF]
Current Opinion in Rheumatology, 2019 Purpose of review To give an overview of recently published articles addressing the mechanisms underlying sex bias in autoimmune disease. Recent findings Recent studies investigating the origins of sex bias in autoimmune disease have revealed an extensive and interconnected network ...
Allison C, Billi +2 more
openaire +2 more sources
Sex-biased avian host use by arbovirus vectors [PDF]
Royal Society Open Science, 2014 Prevalence of arthropod-borne parasites often differs drastically between host sexes. This sex-related disparity may be related to physiological (primarily hormonal) differences that facilitate or suppress replication of the pathogen in host tissues ...
Nathan D. Burkett-Cadena +2 more
doaj +1 more source
Trends in Endocrinology & Metabolism, 2020 In hormone-dependent organs, sex hormones and dysregulated hormone signaling have well-documented roles in cancers of the breast and female reproductive organs including endometrium and ovary, as well as in prostate and testicular cancers in males. Strikingly, epidemiological data highlight significant differences between the sexes in the incidence of ...
Costa, Ana Raquel +5 more
openaire +3 more sources
Sex bias in pain management decisions. [PDF]
Proc Natl Acad Sci U S AIn the pursuit of mental and physical health, effective pain management stands as a cornerstone. Here, we examine a potential sex bias in pain management. Leveraging insights from psychological research showing that females’ pain is stereotypically judged as less intense than males’ pain, we hypothesize that there may be tangible differences in pain ...
Guzikevits M +9 more
europepmc +3 more sources