Exploring sex bias in cardiometabolic diseases [PDF]
Lipids in Health and DiseaseCardiometabolic diseases (CMDs), such as cardiovascular diseases (CVDs), obesity, type 2 diabetes, and metabolic dysfunction-associated steatohepatitis (MASH), represent an alarming burden on healthcare systems. Differences in the prevalence, progression
Tania Guillemette +3 more
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The toll like receptor 7 pathway and the sex bias of systemic lupus erythematosus [PDF]
Frontiers in ImmunologySystemic lupus erythematosus (SLE) predominately affects women with a ratio of females-to-males of about 9:1. The complement of sex chromosomes may play and important role in the mechanism of the sex bias.
R. Hal Scofield +6 more
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Unmasking the Adverse Impacts of Sex Bias on Science and Research Animal Welfare [PDF]
Animals, 2023 Sex bias in biomedical and natural science research has been prevalent for decades. In many cases, the female estrous cycle was thought to be too complex an issue to model for, and it was thought to be simpler to only use males in studies.
Elizabeth A. Nunamaker +1 more
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Comparing the PRISMA-7 and a Modified Version (PRISMA-6) for Frailty Screening: Addressing Sex Bias in Community-Dwelling Older Adults [PDF]
GeriatricsBackground/Objectives: Frailty screening facilitates the identification of older adults at risk of adverse health outcomes. The Program of Research to Integrate Services for the Maintenance of Autonomy 7 (PRISMA-7) is a widely utilised frailty tool ...
Dietmar Ausserhofer +5 more
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Sex Bias in Frailty Screening: A Cross-Sectional Analysis of PRISMA-7 and the Clinical Frailty Scale in Primary Care [PDF]
DiagnosticsBackground/Objectives: Frailty screening is essential in primary care for the early identification of vulnerable older adults. PRISMA-7 is a widely used screening tool, but Item 2 (“Are you male?”) introduces potential sex bias and overestimates frailty ...
Christian J. Wiedermann +5 more
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Sex bias in prospective follow-up observational studies with drugs carried out in a southern region of Europe [PDF]
Frontiers in PharmacologyIntroductionThe impact of sex bias in medical research is a matter of significant relevance and importance especially in the modern age. Despite notable improvements in sex equity across various societal fields, disparities in sex representation persist ...
Àlex Santomà +8 more
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Large-Scale Item-Level Analysis of the Figural Matrices Test in the Norwegian Armed Forces: Examining Measurement Precision and Sex Bias [PDF]
Journal of IntelligenceFigural matrices tests are common in intelligence research and have been used to draw conclusions regarding secular changes in intelligence. However, their measurement properties have seldom been evaluated with large samples that include both sexes ...
Fredrik Helland-Riise +2 more
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Identifying Offspring Sex Ratio Skews in Zoological Facilities Using Large Historical Datasets
Journal of Zoological and Botanical Gardens, 2023 The Fisher principle states that species should produce offspring at a ratio of 1:1 unless there are sex-specific differences in rearing costs. Research conducted across taxa has found that animals will vary the sex ratio of their offspring so as to ...
Julia M. Machado, Lance J. Miller
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Relevance of sex-differenced analyses in bioenergetics and nutritional studies
Frontiers in Nutrition, 2022 Sex-biased analyses still remain as one of the biggest limitations to obtain universal conclusions. In biomedicine, the majority of experimental analyses and a significant amount of patient-derived cohort studies exclusively included males.
Glòria Garrabou +7 more
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A 10-year follow-up study of sex inclusion in the biological sciences
eLife, 2020 In 2016, to address the historical overrepresentation of male subjects in biomedical research, the US National Institutes of Health implemented a policy requiring investigators to consider sex as a biological variable.
Nicole C Woitowich +2 more
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