Results 11 to 20 of about 2,978,590 (198)

Addressing Ancestry and Sex Bias in Pharmacogenomics [PDF]

open access: yesAnnual Review of Pharmacology and Toxicology, 2023
The association of an individual's genetic makeup with their response to drugs is referred to as pharmacogenomics. By understanding the relationship between genetic variants and drug efficacy or toxicity, we are able to optimize pharmacological therapy according to an individual's genotype. Pharmacogenomics research has historically suffered from bias
Corpas, M   +5 more
core   +5 more sources

Sex differences in interpretation bias in adolescents [PDF]

open access: yesBritish Journal of Developmental Psychology, 2014
Interpretation biases, in which ambiguous information is interpreted negatively, have been hypothesized to place adolescent females at greater risk of developing anxiety and mood disorders than same‐aged males. We tested the hypothesis that adolescent girls interpret ambiguous scenarios more negatively, and/or less positively, than
Gluck, Rachel   +3 more
openaire   +6 more sources

Sex bias in autoimmunity [PDF]

open access: yesCurrent Opinion in Rheumatology, 2019
Purpose of review To give an overview of recently published articles addressing the mechanisms underlying sex bias in autoimmune disease. Recent findings Recent studies investigating the origins of sex bias in autoimmune disease have revealed an extensive and interconnected network ...
Allison C, Billi   +2 more
openaire   +2 more sources

Raising awareness of sex and gender bias in artificial intelligence and health [PDF]

open access: yes, 2023
Historically, biomedical research has been led by and focused on men. The recent introduction of Artificial Intelligence (AI) in this area has further proven this practice to be discriminatory for other sexes and genders, more noticeably for women.
Buslón, Nataly   +9 more
core   +1 more source

The Sex Bias of Cancer

open access: yesTrends in Endocrinology & Metabolism, 2020
In hormone-dependent organs, sex hormones and dysregulated hormone signaling have well-documented roles in cancers of the breast and female reproductive organs including endometrium and ovary, as well as in prostate and testicular cancers in males. Strikingly, epidemiological data highlight significant differences between the sexes in the incidence of ...
Costa, Ana Raquel   +5 more
openaire   +3 more sources

Alternative migratory tactics in brown trout (Salmo trutta) are underpinned by divergent regulation of metabolic but not neurological genes

open access: yesEcology and Evolution, 2021
The occurrence of alternative morphs within populations is common, but the underlying molecular mechanisms remain poorly understood. Many animals, for example, exhibit facultative migration, where two or more alternative migratory tactics (AMTs) coexist ...
Robert Wynne   +11 more
doaj   +1 more source

Estrogen Receptor Alpha Signaling Is Responsible for the Female Sex Bias in the Loss of Tolerance and Immune Cell Activation Induced by the Lupus Susceptibility Locus Sle1b

open access: yesFrontiers in Immunology, 2020
The dramatic female sex bias observed in human lupus is thought to be due, at least in part, to estrogens. Using mouse models, we have shown that estrogens, acting through estrogen receptor alpha (ERα) promote lupus development and contribute ...
Jared H. Graham   +2 more
doaj   +1 more source

Increased Circulating Cytokines Have a Role in COVID-19 Severity and Death With a More Pronounced Effect in Males: A Systematic Review and Meta-Analysis

open access: yesFrontiers in Pharmacology, 2022
Background: Coronavirus disease 2019 (COVID-2019), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has become a worldwide epidemic and claimed millions of lives.
Huating Hu   +7 more
doaj   +1 more source

Ideological Bias in the Psychology of Sex and Gender [PDF]

open access: yes, 2023
This chapter discusses the influence of ideological bias in the psychological study of sex and gender, with a focus on academic psychology. After introducing the essence of the problem, the chapter examines the conceptual distinction between "sex" and ...
Del Giudice, Marco
core   +1 more source

Sex and Credit:Is There a Gender Bias in Lending? [PDF]

open access: yesSSRN Electronic Journal, 2012
Abstract: We exploit the quasi-random assignment of borrowers to loan officers using data from a large Albanian lender to show that own-gender preferences affect both credit supply and demand. Borrowers matched to officers of the opposite gender are less likely to return for a second loan.
Beck, T.H.L., Behr, P., Madestam, A.
openaire   +5 more sources

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