Ontogenetic Change in Male Expression of Testosterone-Responsive Genes Contributes to the Emergence of Sex-Biased Gene Expression in Anolis sagrei [PDF]
Sex differences in gene expression tend to increase with age across a variety of species, often coincident with the development of sexual dimorphism and maturational changes in hormone levels. However, because most transcriptome-wide characterizations of
Matthew D. Hale +3 more
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Postnatal developmental trajectory of sex-biased gene expression in the mouse pituitary gland [PDF]
Highlights Male and female mouse pituitary gland gene and miRNA expression was profiled across five postnatal ages spanning pubertal development. Sex differences in pituitary gene expression exist prior to puberty and become more prominent upon puberty ...
Huayun Hou +13 more
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Fast evolutionary turnover and overlapping variances of sex-biased gene expression patterns defy a simple binary sex classification of somatic tissues [PDF]
Sexual dimorphism in phenotypes is largely driven by genes with sex-biased expression, spanning from key regulators to numerous organ-specific effectors.
Chen Xie, Sven Künzel, Diethard Tautz
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Sex-biased gene and microRNA expression in the developing mouse brain is associated with neurodevelopmental functions and neurological phenotypes [PDF]
Background Sex differences pose a challenge and an opportunity in biomedical research. Understanding how sex chromosomes and hormones affect disease-causing mechanisms will shed light on the mechanisms underlying predominantly idiopathic sex-biased ...
Susanna Szakats +3 more
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Impact of male trait exaggeration on sex-biased gene expression and genome architecture in a water strider [PDF]
Background Exaggerated secondary sexual traits are widespread in nature and often evolve under strong directional sexual selection. Although heavily studied from both theoretical and empirical viewpoints, we have little understanding of how sexual ...
William Toubiana +4 more
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Harnessing natural variation to identify cis regulators of sex-biased gene expression in a multi-strain mouse liver model. [PDF]
Sex differences in gene expression are widespread in the liver, where many autosomal factors act in tandem with growth hormone signaling to regulate individual variability of sex differences in liver metabolism and disease.
Bryan J Matthews +2 more
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Two novel genomes of fireflies with different degrees of sexual dimorphism reveal insights into sex-biased gene expression and dosage compensation [PDF]
Sexual dimorphism arises because of divergent fitness optima between the sexes. Phenotypic divergence between sexes can range from mild to extreme. Fireflies, bioluminescent beetles, present various degrees of sexual dimorphism, with species showing very
Ana Catalán +5 more
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Identification of sex chromosome, sex-biased gene expression and dosage compensation in the pygmy mole cricket Xya riparia (Orthoptera: Tridactyloidea) [PDF]
Background Sex-biased gene expression and sex chromosome dosage compensation are crucial for the growth and development of sexually reproducing organisms.
Yimeng Nie +3 more
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Sex‐biased dispersal and spatial heterogeneity affect landscape resistance to gene flow in fisher
Genetic connectivity results from the dispersal and reproduction of individuals across landscapes. Mammalian populations frequently exhibit sex‐biased dispersal, but this factor has rarely been addressed in individual‐based landscape genetics research ...
Jody M. Tucker +3 more
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Sexual dimorphism and sex-biased gene expression in an egg parasitoid species, Anastatus disparis [PDF]
Background Differences in the expression of genes present in both sexes are assumed to contribute to sex differences including behavioural, physiological and morphological dimorphisms. For enriching our knowledge of gender differences in an important egg
Peng-Cheng Liu +3 more
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